Pharmaceutical and Chemical Quiz
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Questions and Answers

What is the main function of physiologically inert substances added to tablets?

  • Increasing stability
  • Facilitating swallowing (correct)
  • Improving flavor
  • Enhancing bioavailability
  • Which of the following substances is best suited as an astringent?

  • Caustic agent (correct)
  • Anti-fungal lotion
  • Hydrating cream
  • Moisturizing ointment
  • Which radiopharmaceutical agent is most effective for bone imaging?

  • Tc99m etidronate (correct)
  • Tc99m albumin colloid
  • Tc99m Ferpentate
  • Tc99m IDA
  • Which mechanism does NOT typically represent anti-microbial action?

    <p>Precipitation</p> Signup and view all the answers

    What ion presents a white precipitate with HCl that is soluble in excess ammonium hydroxide?

    <p>Plumbous ions</p> Signup and view all the answers

    An agent that tends to gain electrons in a redox reaction is known as what?

    <p>Oxidizing agent</p> Signup and view all the answers

    According to the law of mass action, the rate of a reaction is proportional to what?

    <p>Product of reactant concentrations</p> Signup and view all the answers

    Which substance is used topically as an astringent and protectant in ointment?

    <p>ZnO</p> Signup and view all the answers

    What color is nickel ion in solution typically classified as?

    <p>Green</p> Signup and view all the answers

    What term describes a substance that takes up moisture but does not dissolve?

    <p>Hygroscopic</p> Signup and view all the answers

    What is ammonia primarily used as?

    <p>Respiratory stimulant</p> Signup and view all the answers

    Which agent is used to kill microorganisms on inanimate objects?

    <p>Disinfectant</p> Signup and view all the answers

    What is laughing gas commonly referred to?

    <p>General anesthetic</p> Signup and view all the answers

    Which laxative increases osmotic load in the gastrointestinal tract?

    <p>Saline cathartic</p> Signup and view all the answers

    Which inert gas has anesthetic properties?

    <p>Argon</p> Signup and view all the answers

    Which ion produces a Prussian blue precipitate with potassium ferrocyanide?

    <p>Ferrous</p> Signup and view all the answers

    What type of oxides do typically non-metallic elements form?

    <p>Acidic</p> Signup and view all the answers

    Which law describes the relationship between pressure, volume, and temperature of gases?

    <p>Ideal Gas Law</p> Signup and view all the answers

    Which group of metallic elements is considered the most active?

    <p>Alkali metals</p> Signup and view all the answers

    What attractive forces are created by the polarizability of molecules when uncharged atoms approach closely?

    <p>Van der Waals Forces</p> Signup and view all the answers

    Which of the following elements is poisonous even in its free metal form?

    <p>Mercury</p> Signup and view all the answers

    Identify the option that is not a salt of chlorine.

    <p>Rock salt</p> Signup and view all the answers

    What renders benzalkonium chloride inactive as a germicidal surfactant?

    <p>Soaps (anion agents)</p> Signup and view all the answers

    What process does dimercaprol (BAL) use to act as an antidote?

    <p>Chelation</p> Signup and view all the answers

    Which method is NOT a sterilization technique?

    <p>Dry heating at 160°C for 2 hours</p> Signup and view all the answers

    Which of the following is a systemic antacid?

    <p>Sodium bicarbonate</p> Signup and view all the answers

    NH4Cl is contraindicated in patients with which condition?

    <p>Respiratory alkalosis</p> Signup and view all the answers

    Which radiopharmaceutical is used for hepatobiliary studies?

    <p>Sodium iodophippurate I-131</p> Signup and view all the answers

    What is the indicator used for the USP limit test for arsenic?

    <p>Ag diethyldithiocarbamate</p> Signup and view all the answers

    Povidone-Iodine is a complex of iodine with which substance?

    <p>Polyvinyl pyrrolidone</p> Signup and view all the answers

    Zinc deficiency resulting in thickened scaly inflamed skin is known as?

    <p>Parakeratosis</p> Signup and view all the answers

    Primary HCO3 excess is indicative of which condition?

    <p>Metabolic alkalosis</p> Signup and view all the answers

    What is the major side effect from the use of barium sulfate suspension as a radiopaque agent?

    <p>Vomiting</p> Signup and view all the answers

    Which alum silicate is known to have antidiarrheal properties?

    <p>Kaolin</p> Signup and view all the answers

    Which salt is contained in Fehling’s & Benedict’s reagent to test for reducing sugars?

    <p>CuSO4</p> Signup and view all the answers

    What substance is added to glass to enhance its coefficient of expansion?

    <p>Boron (B)</p> Signup and view all the answers

    Which vitamin is known to enhance the utilization of calcium in the body?

    <p>Vitamin D</p> Signup and view all the answers

    What deficiency is primarily responsible for causing goiter?

    <p>Iodine</p> Signup and view all the answers

    Which alkaline metal salt is utilized as a sedative depressant in psychiatric treatment?

    <p>Lithium</p> Signup and view all the answers

    Which ion is essential for life, serving as the structural basis of the skeleton and playing a role in blood coagulation?

    <p>Calcium (Ca)</p> Signup and view all the answers

    Study Notes

    Barium Sulfate Suspension

    • Barium sulfate suspension's major side effect is vomiting.

    Alum Silicates

    • The alum silicate that acts as an antidiarrheal is attapulgite.

    Reducing Sugar Tests

    • Fehling's and Benedict's reagents are employed to detect the presence of reducing sugars.
    • These reagents contain copper sulfate (CuSO4).

    Glass Composition

    • Boron (B) is added to glass to improve its coefficient of expansion.
    • The coefficient of expansion refers to how much the glass expands or contracts with temperature changes.
    • Boron helps to prevent rapid expansion and contraction.

    Calcium and Vitamin D

    • Vitamin D enhances the absorption of calcium in the body.
    • Calcium is important for skeletal structure and blood coagulation.

    Goiter

    • Goiter, a thyroid disorder, is caused by a deficiency of iodine.

    Lithium and Sedatives

    • Lithium salts are used as sedative-depressants in psychiatry.

    Hemoglobin

    • Iron (Fe) is the element present in hemoglobin.
    • Hemoglobin is a protein in red blood cells that carries oxygen throughout the body.

    Universal Antidote

    • The universal antidote contains magnesium oxide (MgO), activated charcoal, and tannic acid.

    Astringents

    • Zinc oxide (ZnO) is used topically in ointments as an astringent and protectant.
    • Astringents help to constrict tissues and stop bleeding.

    Hygroscopic Substances

    • Hygroscopic substances absorb water from the atmosphere but do not dissolve.

    Ammonia

    • Ammonia is used as a respiratory stimulant.

    Disinfectants

    • Disinfectants are used to kill microorganisms on inanimate objects.

    Laughing Gas

    • Laughing gas is a general anesthetic.

    Laxatives

    • Saline cathartics increase the osmotic load of the gastrointestinal tract.
    • This increases the water content in the intestines, leading to a laxative effect.

    Anesthesia and Inert Gases

    • Krypton is an inert gas with anesthetic properties.

    Turnbull's Blue

    • The ferrous ion (Fe2+) produces a Turnbull's blue precipitate with potassium ferricyanide.

    Mercurous Ions

    • Mercurous ions (Hg2+2) form a white precipitate with hydrochloric acid.
    • This precipitate turns black upon the addition of ammonium hydroxide.

    Manganese and Sodium Bismuthate

    • Manganese ions react with sodium bismuthate to produce a purple solution.

    Talc

    • Talc is a native hydrous magnesium silicate.

    Prussian Blue

    • The ferric ion (Fe3+) produces a Prussian blue precipitate with potassium ferrocyanide.

    Carbon and Antidiarrheals

    • Carbon acts as an antidiarrheal by adsorption.

    Pharmaceutical Diluents

    • Diluents are physiologically inert substances added to tablets to make them easier to swallow.

    Astringents

    • Astringents have various applications, including:
      • Anti-perspirant
      • Caustic
      • Styptic

    Bone Imaging

    • Technetium-99m etidronate (Tc99m etidronate) is the best radiopharmaceutical agent for bone imaging.

    Antimicrobial Mechanisms

    • Hydrolysis is not a mechanism of antimicrobial action.
    • Other mechanisms include oxidation, halogenation, and precipitation.

    Silver Ions

    • Silver ions (Ag+) form a white precipitate with hydrochloric acid.
    • This precipitate dissolves in excess ammonium hydroxide but re-precipitates upon the addition of nitric acid.

    Rinman's Green Test

    • Zinc ions give a positive Rinman's green test.

    Law of Mass Action

    • The Law of Mass Action states that the rate of a reaction is proportional to the product of the concentrations of the reactants raised to the power of their respective coefficients in the balanced equation.

    Reducing Agent

    • A reducing agent loses one or more electrons in a redox reaction.

    Nickel Ion Color

    • Nickel ions in solution are green.

    Amphoteric Oxides

    • Oxides of typically non-metallic elements are amphoteric.

    Ideal Gas Law

    • The Ideal Gas Law describes the relationship between pressure, volume, and temperature for gases.
    • The equation is: PV = nRT, where n represents the number of moles of gas and R is the ideal gas constant.

    Alkali Metals

    • Alkali metals are the most active of metallic elements.

    Van Der Waals Forces

    • Van Der Waals forces are attractive forces created by the polarization of molecules.
    • These forces occur when two uncharged atoms approach each other very closely.

    Mercury Toxicity

    • Mercury is poisonous even in its free metal form.

    Chlorine Salts

    • Saltpeter (KNO3) is not a salt of chlorine.
    • Other chlorine salts include rock salt (NaCl) and bleaching powder (CaOCl2).

    Benzalkonium Chloride

    • Benzalkonium chloride is a germicidal surfactant that becomes inactive in the presence of soaps (anion agents).

    Phosphine Gas

    • Phosphine (PH3) is a gas liberated when water reacts with acids or metals in the presence of phosphorus as a contaminant.

    Atomic Absorption Spectroscopy

    • Atomic absorption spectroscopy is used to detect trace amounts of metal contaminants.

    Dimercaprol

    • Dimercaprol (BAL) acts as an antidote by chelation.

    Sterilization Methods

    • Sterilization methods include:
      • Heating in an autoclave
      • Heating in an open vessel, re-saturating with sterile CO2
      • Bacteriological filtration

    Non-Systemic Antacids

    • Sodium bicarbonate (NaHCO3) is a systemic antacid.
    • Non-systemic antacids include aluminum hydroxide, dihydroxy aluminum sodium carbonate, and calcium carbonate.

    Ammonium Chloride

    • Ammonium chloride (NH4Cl) is contraindicated in patients with impaired hepatic function.
    • The rationale is that NH4Cl can contribute to metabolic acidosis, which can be harmful in the presence of liver problems since the liver plays a vital role in acid-base balance.

    Hepatobiliary Studies

    • Technetium-99m-HIDA (Tc-99m-HIDA) is a radiopharmaceutical used for hepatobiliary studies.

    USP Limit Test for Arsenic

    • Silver diethyldithiocarbamate is the indicator used for the USP limit test for arsenic.

    Povidone-Iodine

    • Povidone-iodine is a complex of iodine with polyvinyl pyrrolidone.

    Zinc Deficiency

    • Zinc deficiency can lead to parakeratosis, a condition characterized by thickened, scaly, and inflamed skin.

    Metabolic Alkalosis

    • Primary HCO3 excess is characterized by metabolic alkalosis.

    Hyperchloremia

    • Dehydration and decreased renal blood flow can lead to hyperchloremia (high chloride levels in the blood).

    Respiratory Stimulants

    • Soda lime is not a respiratory stimulant.
    • Respiratory stimulants include carbon dioxide, ammonium carbonate, and aromatic ammonia spirit.

    Anemia

    • Anemia due to decreased blood formation can be caused by deficiencies of key materials like cobalamin (vitamin B12).

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    Description

    Test your knowledge on various pharmaceutical and chemical concepts, including the effects of barium sulfate and the role of vitamin D in calcium absorption. Explore topics such as reducing sugar tests and the significance of boron in glass composition. This quiz covers important aspects of chemistry and pharmacology.

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