12 Questions
Which class of antibiotics inhibits cell wall synthesis?
Sulfonamides
What is the mechanism of action of vancomycin?
Inhibiting cell wall synthesis
Which antibiotic may have both bactericidal and bacteriostatic activity depending on the dose or specific bacteria?
Tetracyclines
What is a common mechanism of resistance to antibiotics?
Misuse and overuse of antibiotics
Which of the following is a possible hypothesis for the interaction between oral contraceptives (OCs) and antibiotics?
Increased enterohepatic circulation
Which category of antibacterial drugs is associated with a 13 fold increase in the risk of unintended pregnancies when taken with oral contraceptives?
Rifampicin
Which organization does not advise any additional precautions despite the uncertainties regarding the interaction between antibiotics and oral contraceptives?
World Health Organization (WHO)
Which enzyme-inducing drug is mentioned in the text as posing a risk of unintended pregnancies when taken with oral contraceptives?
Carbamazepine
What is a potential mechanism by which fluoroquinolones increase the effect of warfarin?
Inhibition of warfarin metabolism
How do macrolides such as azithromycin and erythromycin affect the metabolism of warfarin?
They inhibit hepatic metabolism of warfarin
What is a consideration for penicillins in relation to warfarin use?
They displace warfarin from protein binding sites
What is a potential effect of sulfonamides on warfarin therapy?
Altered gut flora affecting vitamin K synthesis
This quiz covers the interactions between antibiotics and warfarin, focusing on considerations for cephalosporins and fluoroquinolones. Topics include how these antibiotics might affect warfarin's effectiveness and the importance of monitoring INR levels.
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