Pharm Focused Review: Dementia and Alzheimer Disease

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10 Questions

What is the main pathological feature in Alzheimer Disease?

Formation of neurofibrillary tangles with hyperphosphorylated Tau proteins

What is considered a reversible cause of dementia?

Thyroid disorders

Which neurotransmitter is decreased in Alzheimer Disease and leads to excessive stimulation of glutamate?

Acetylcholine

What is the initial treatment choice for mild to moderate Alzheimer Disease?

Cholinesterase inhibitors

Which medication may be considered if there is no response to cholinesterase inhibitors within 3-6 months?

Another cholinesterase inhibitor

What symptom is NOT associated with antipsychotic medication?

Confusion

Which of the following is NOT a side effect of Memantine (Namenda)?

Respiratory depression

Why is rivastigmine considered to have an advantage over other cholinesterase inhibitors?

It is not metabolized by the P450 enzyme system

Which symptom is characteristic of akathisia in patients receiving antipsychotic medication?

Restlessness

What is a key consideration for using risperidone in patients with Parkinson's disease?

Higher risk of extrapyramidal symptoms

This quiz focuses on the formation of neurofibrillary tangles, plaques, cortical atrophy, and neuronal destruction associated with Dementia and Alzheimer's Disease. It covers the causes of dementia including Apolipoprotein E, advanced age, traumatic brain injury, and lack of social interaction.

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