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Questions and Answers
What is the primary mechanism of neuronal toxicity in Alzheimer's disease?
What is the primary mechanism of neuronal toxicity in Alzheimer's disease?
- Increased levels of serotonin in the brain
- Excessive stimulation of glutamate receptors (correct)
- Excessive stimulation of acetylcholine receptors
- Decreased levels of dopamine in the brain
Which apolipoprotein is involved in cholesterol transport and linked to the development of Alzheimer's disease?
Which apolipoprotein is involved in cholesterol transport and linked to the development of Alzheimer's disease?
- Apolipoprotein D
- Apolipoprotein A
- Apolipoprotein E (correct)
- Apolipoprotein C
What is the most common type of dementia?
What is the most common type of dementia?
- Frontotemporal dementia
- Lewy body dementia
- Alzheimer's disease (correct)
- Vascular dementia
Which medication class is associated with reversible dementia?
Which medication class is associated with reversible dementia?
What is the primary neurotransmitter depleted in Alzheimer's disease?
What is the primary neurotransmitter depleted in Alzheimer's disease?
Which of the following is NOT a reversible cause of dementia?
Which of the following is NOT a reversible cause of dementia?
What is the primary mechanism of action of cholinesterase inhibitors?
What is the primary mechanism of action of cholinesterase inhibitors?
What is the typical duration of treatment with cholinesterase inhibitors before reassessment?
What is the typical duration of treatment with cholinesterase inhibitors before reassessment?
Which of the following is a common side effect of cholinesterase inhibitors?
Which of the following is a common side effect of cholinesterase inhibitors?
Which of the following medications is NOT a cholinesterase inhibitor?
Which of the following medications is NOT a cholinesterase inhibitor?
Which condition may be treated with aripiprazole, a partial dopamine agonist?
Which condition may be treated with aripiprazole, a partial dopamine agonist?
What is a potential risk associated with anticonvulsants like divalproex, carbamazepine, oxcarbazepine, and lamotrigine?
What is a potential risk associated with anticonvulsants like divalproex, carbamazepine, oxcarbazepine, and lamotrigine?
Which neurotransmitter system is targeted by memantine (Namenda) in Alzheimer's disease?
Which neurotransmitter system is targeted by memantine (Namenda) in Alzheimer's disease?
What is a potential side effect of antipsychotic medications like haloperidol and trifluoperazine?
What is a potential side effect of antipsychotic medications like haloperidol and trifluoperazine?
What is the main goal of Alzheimer's medication therapy?
What is the main goal of Alzheimer's medication therapy?
What is a symptom commonly associated with akathisia caused by antipsychotic medications?
What is a symptom commonly associated with akathisia caused by antipsychotic medications?
Why is risperidone cautioned in patients with Parkinson's disease?
Why is risperidone cautioned in patients with Parkinson's disease?
Which symptom is NOT associated with extrapyramidal side effects due to antipsychotic medications?
Which symptom is NOT associated with extrapyramidal side effects due to antipsychotic medications?
Which enzyme system is responsible for the metabolism of tacrine, donepezil, and galantamine?
Which enzyme system is responsible for the metabolism of tacrine, donepezil, and galantamine?
What is a distinguishing advantage of rivastigmine over other cholinesterase inhibitors?
What is a distinguishing advantage of rivastigmine over other cholinesterase inhibitors?
Which atypical antipsychotic should be avoided in patients with a prolonged QT interval?
Which atypical antipsychotic should be avoided in patients with a prolonged QT interval?
Which typical (1st generation) antipsychotic is associated with the least risk of metabolic syndrome?
Which typical (1st generation) antipsychotic is associated with the least risk of metabolic syndrome?
Which statement about dementia and benzodiazepines is accurate?
Which statement about dementia and benzodiazepines is accurate?
What is the primary mode of action of benzodiazepines in the CNS?
What is the primary mode of action of benzodiazepines in the CNS?
Which benzodiazepine is commonly used in older adults due to its lower risk of adverse effects?
Which benzodiazepine is commonly used in older adults due to its lower risk of adverse effects?
What is the major concern regarding concurrent use of benzodiazepines and opioids?
What is the major concern regarding concurrent use of benzodiazepines and opioids?
Which antipsychotic is preferred for patients with Parkinson's disease–related psychosis?
Which antipsychotic is preferred for patients with Parkinson's disease–related psychosis?
In patients with poor compliance or high risk of relapse, what type of antipsychotic formulation may be considered?
In patients with poor compliance or high risk of relapse, what type of antipsychotic formulation may be considered?
What should be assessed in patients previously treated for anxiety before starting benzodiazepines?
What should be assessed in patients previously treated for anxiety before starting benzodiazepines?
Which antipsychotic carries the highest risk of tardive dyskinesia?
Which antipsychotic carries the highest risk of tardive dyskinesia?
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