Pertussis (Whooping Cough) Disease

Droplet infection through respiratory droplets

Severe cough often ending in vomiting, cyanosis, and loss of oxygen exchange in severe cases

Inhibits complement, survives within phagocytes, inhibits recruitment of immune cells, and suppresses antibody production

<p>First year of life, young children, and young adults</p> Signup and view all the answers

<p>LOS inhibits the recognition by surfactant A and inhibits complement</p> Signup and view all the answers

<p>Adherence to and destruction of ciliated cells, leading to ciliary stasis and mucous accumulation</p> Signup and view all the answers

<p>Maximum communicability during this stage</p> Signup and view all the answers

<p>Slow-growing and requires selective media for primary isolation</p> Signup and view all the answers

<p>The primary cause of whooping cough is the bacteria Bordetella pertussis, which grows on the surface of the respiratory tract, producing a powerful toxin that kills ciliated respiratory epithelia, leading to damage and swelling of the airway.</p> Signup and view all the answers

<p>In infants, the symptoms of whooping cough may include apnea and difficulty breathing, whereas in older children, it is characterized by a persistent cough, often referred to as the '100 days cough'.</p> Signup and view all the answers

<p>The recommended treatment for whooping cough includes antibiotics such as Erythromycin, which should be started early to reduce the severity of the disease and prevent further spread.</p> Signup and view all the answers

<p>Vaccinating pregnant women against whooping cough helps to protect their infants, with a 90% effectiveness rate in preventing the disease.</p> Signup and view all the answers

<p>Boosting the immunity of individuals in contact with infants helps to prevent the spread of whooping cough, as immunity to the disease fades quickly, and those in close contact with infants are at higher risk of transmission.</p> Signup and view all the answers

<p>The genus Bordetella has 8 species, with 4 species having motile peritrichous flagellae.</p> Signup and view all the answers

<p>The vaccine against whooping cough is an acellular vaccine made from inactivated toxin, which helps to prevent the disease by inducing immunity against the toxin.</p> Signup and view all the answers