Podcast
Questions and Answers
What is the main route of entry for Bordetella pertussis into the human body?
What is the main route of entry for Bordetella pertussis into the human body?
Inhalation
What is the function of Pertussis toxin (PT)?
What is the function of Pertussis toxin (PT)?
ADP-ribosylates GTP-binding protein (Gi)
How does filamentous hemagglutinin (FHA) contribute to Bordetella pertussis virulence?
How does filamentous hemagglutinin (FHA) contribute to Bordetella pertussis virulence?
Allows adherence to ciliated epithelial cells
What is the significance of the RGD loops in Pertactin (Prn)?
What is the significance of the RGD loops in Pertactin (Prn)?
How does Bordetella pertussis damage neurons during infection?
How does Bordetella pertussis damage neurons during infection?
What is the action of Adenylate cyclase toxin (ACT / CyaA) on target cells?
What is the action of Adenylate cyclase toxin (ACT / CyaA) on target cells?
How does the acellular pertussis vaccine differ from the heat-killed vaccine?
How does the acellular pertussis vaccine differ from the heat-killed vaccine?
What are the characteristics of Bordetella pertussis in terms of size and shape?
What are the characteristics of Bordetella pertussis in terms of size and shape?
What are the two types of fimbriae present in Bordetella pertussis?
What are the two types of fimbriae present in Bordetella pertussis?
What is the main stage of whooping cough characterized by fits of rapid coughing and the 'whooping' sound?
What is the main stage of whooping cough characterized by fits of rapid coughing and the 'whooping' sound?
Flashcards
B. pertussis entry
B. pertussis entry
Enters via inhalation.
Pertussis toxin (PT) function
Pertussis toxin (PT) function
Modifies Gi protein via ADP-ribosylation.
FHA role in virulence
FHA role in virulence
Aids in adherence to ciliated respiratory cells.
RGD loops in Pertactin (Prn)
RGD loops in Pertactin (Prn)
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Adenylate cyclase toxin (ACT)
Adenylate cyclase toxin (ACT)
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Acellular pertussis vaccine
Acellular pertussis vaccine
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B. pertussis characteristics
B. pertussis characteristics
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B. pertussis fimbriae types
B. pertussis fimbriae types
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Paroxysmal stage
Paroxysmal stage
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B. pertussis damages neurons
B. pertussis damages neurons
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