Podcast Beta
Questions and Answers
What is the main route of entry for Bordetella pertussis into the human body?
Inhalation
What is the function of Pertussis toxin (PT)?
ADP-ribosylates GTP-binding protein (Gi)
How does filamentous hemagglutinin (FHA) contribute to Bordetella pertussis virulence?
Allows adherence to ciliated epithelial cells
What is the significance of the RGD loops in Pertactin (Prn)?
Signup and view all the answers
How does Bordetella pertussis damage neurons during infection?
Signup and view all the answers
What is the action of Adenylate cyclase toxin (ACT / CyaA) on target cells?
Signup and view all the answers
How does the acellular pertussis vaccine differ from the heat-killed vaccine?
Signup and view all the answers
What are the characteristics of Bordetella pertussis in terms of size and shape?
Signup and view all the answers
What are the two types of fimbriae present in Bordetella pertussis?
Signup and view all the answers
What is the main stage of whooping cough characterized by fits of rapid coughing and the 'whooping' sound?
Signup and view all the answers
