Personalized Medicine in Gout Treatment
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Questions and Answers

What is the primary focus of personalized medicine in the context of the text?

  • Developing new drug therapies for rheumatoid arthritis
  • Prescribing drugs based on patient risk factors to prevent adverse events (correct)
  • Treating established drug toxicity
  • Improving the management of chronic diseases like diabetes and cardiovascular disease

    • Which of the following approaches is useful for adjusting drug doses in gout treatment?

  • Genetic testing
  • Pharmacokinetic monitoring
  • Adaptive trial design (correct)
  • Combination therapy

    • What is the primary advantage of using adaptive trial design in gout treatment, as discussed in the text?

  • It can improve the efficacy of urate lowering drugs
  • It can better include patients with multiple comorbidities in clinical trials
  • It can reduce the burden of a substantial pill and disease
  • It can identify the best treatment for specific patient phenotypes in a shorter time span (correct)

    • Which of the following is a key limitation of existing clinical trials in gout management?

    <p>They have not included patients with multiple comorbidities</p> Signup and view all the answers

    What is the primary purpose of the BSR/BHPR guideline mentioned in the text?

    <p>To divide gout patients into those receiving urate lowering therapy and those not receiving it</p> Signup and view all the answers

    What is the key challenge or limitation in gout management that the text suggests can be addressed through personalized medicine approaches?

    <p>The need to improve the efficacy of gout treatments and reduce tophi burden</p> Signup and view all the answers

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