5 Questions
Which of the following contributes to the persistence of the fetal circulatory pattern in Persistent Pulmonary Hypertension (PPHN)?
Excessively high pulmonary vascular resistance (PVR)
In PPHN, what does the PaO2 or oxygen saturation gradient between preductal and post-ductal sites of blood sampling suggest?
Right-to-left shunting through the ductus arteriosus
What is the consequence of chronic fetal hypoxia in the pathogenesis of PPHN?
Increased pulmonary artery medial muscle thickness
What is helpful in diagnosing PPHN?
2D echo with Doppler
Which condition is associated with obstructive PPHN?
Total Anomalous Pulmonary Venous Return (TAPVR)
Study Notes
Persistence of Fetal Circulatory Pattern in PPHN
- Hypoxia and acidosis contribute to the persistence of the fetal circulatory pattern in Persistent Pulmonary Hypertension (PPHN)
Diagnosis of PPHN
- A PaO2 or oxygen saturation gradient between preductal and post-ductal sites of blood sampling suggests right-to-left shunting and diagnoses PPHN
- Chronic fetal hypoxia is a consequence in the pathogenesis of PPHN
Associated Conditions
- Meconium aspiration syndrome is associated with obstructive PPHN
Test your knowledge of Persistent Pulmonary Hypertension (PPHN) with this quiz. Explore the pathogenesis, right-to-left shunting, PVR dynamics, and factors influencing PVR decline in neonates.
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