Persistent Pulmonary Hypertension (PPHN) Quiz
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Questions and Answers

Which of the following contributes to the persistence of the fetal circulatory pattern in Persistent Pulmonary Hypertension (PPHN)?

  • Reduced pulmonary artery medial muscle thickness
  • Excessively high pulmonary vascular resistance (PVR) (correct)
  • Low postnatal PaO2
  • Decreased pH in the postnatal period
  • In PPHN, what does the PaO2 or oxygen saturation gradient between preductal and post-ductal sites of blood sampling suggest?

  • Left-to-right shunting through the foramen ovale
  • Obstruction in the pulmonary artery
  • Right-to-left shunting through the ductus arteriosus (correct)
  • Normal pulmonary circulation
  • What is the consequence of chronic fetal hypoxia in the pathogenesis of PPHN?

  • Increased pulmonary artery medial muscle thickness (correct)
  • Normalization of pulmonary vascular resistance
  • Reduction in PaCO2 levels
  • Decreased smooth muscle extension into peripheral pulmonary arterioles
  • What is helpful in diagnosing PPHN?

    <p>2D echo with Doppler</p> Signup and view all the answers

    Which condition is associated with obstructive PPHN?

    <p>Total Anomalous Pulmonary Venous Return (TAPVR)</p> Signup and view all the answers

    Study Notes

    Persistence of Fetal Circulatory Pattern in PPHN

    • Hypoxia and acidosis contribute to the persistence of the fetal circulatory pattern in Persistent Pulmonary Hypertension (PPHN)

    Diagnosis of PPHN

    • A PaO2 or oxygen saturation gradient between preductal and post-ductal sites of blood sampling suggests right-to-left shunting and diagnoses PPHN
    • Chronic fetal hypoxia is a consequence in the pathogenesis of PPHN

    Associated Conditions

    • Meconium aspiration syndrome is associated with obstructive PPHN

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    Description

    Test your knowledge of Persistent Pulmonary Hypertension (PPHN) with this quiz. Explore the pathogenesis, right-to-left shunting, PVR dynamics, and factors influencing PVR decline in neonates.

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