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Questions and Answers
Which of the following contributes to the persistence of the fetal circulatory pattern in Persistent Pulmonary Hypertension (PPHN)?
Which of the following contributes to the persistence of the fetal circulatory pattern in Persistent Pulmonary Hypertension (PPHN)?
- Reduced pulmonary artery medial muscle thickness
- Excessively high pulmonary vascular resistance (PVR) (correct)
- Low postnatal PaO2
- Decreased pH in the postnatal period
In PPHN, what does the PaO2 or oxygen saturation gradient between preductal and post-ductal sites of blood sampling suggest?
In PPHN, what does the PaO2 or oxygen saturation gradient between preductal and post-ductal sites of blood sampling suggest?
- Left-to-right shunting through the foramen ovale
- Obstruction in the pulmonary artery
- Right-to-left shunting through the ductus arteriosus (correct)
- Normal pulmonary circulation
What is the consequence of chronic fetal hypoxia in the pathogenesis of PPHN?
What is the consequence of chronic fetal hypoxia in the pathogenesis of PPHN?
- Increased pulmonary artery medial muscle thickness (correct)
- Normalization of pulmonary vascular resistance
- Reduction in PaCO2 levels
- Decreased smooth muscle extension into peripheral pulmonary arterioles
What is helpful in diagnosing PPHN?
What is helpful in diagnosing PPHN?
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Which condition is associated with obstructive PPHN?
Which condition is associated with obstructive PPHN?
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Study Notes
Persistence of Fetal Circulatory Pattern in PPHN
- Hypoxia and acidosis contribute to the persistence of the fetal circulatory pattern in Persistent Pulmonary Hypertension (PPHN)
Diagnosis of PPHN
- A PaO2 or oxygen saturation gradient between preductal and post-ductal sites of blood sampling suggests right-to-left shunting and diagnoses PPHN
- Chronic fetal hypoxia is a consequence in the pathogenesis of PPHN
Associated Conditions
- Meconium aspiration syndrome is associated with obstructive PPHN
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Description
Test your knowledge of Persistent Pulmonary Hypertension (PPHN) with this quiz. Explore the pathogenesis, right-to-left shunting, PVR dynamics, and factors influencing PVR decline in neonates.
