Persistent Pulmonary Hypertension (PPHN) Quiz

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5 Questions

Which of the following contributes to the persistence of the fetal circulatory pattern in Persistent Pulmonary Hypertension (PPHN)?

Excessively high pulmonary vascular resistance (PVR)

In PPHN, what does the PaO2 or oxygen saturation gradient between preductal and post-ductal sites of blood sampling suggest?

Right-to-left shunting through the ductus arteriosus

What is the consequence of chronic fetal hypoxia in the pathogenesis of PPHN?

Increased pulmonary artery medial muscle thickness

What is helpful in diagnosing PPHN?

2D echo with Doppler

Which condition is associated with obstructive PPHN?

Total Anomalous Pulmonary Venous Return (TAPVR)

Study Notes

Persistence of Fetal Circulatory Pattern in PPHN

  • Hypoxia and acidosis contribute to the persistence of the fetal circulatory pattern in Persistent Pulmonary Hypertension (PPHN)

Diagnosis of PPHN

  • A PaO2 or oxygen saturation gradient between preductal and post-ductal sites of blood sampling suggests right-to-left shunting and diagnoses PPHN
  • Chronic fetal hypoxia is a consequence in the pathogenesis of PPHN

Associated Conditions

  • Meconium aspiration syndrome is associated with obstructive PPHN

Test your knowledge of Persistent Pulmonary Hypertension (PPHN) with this quiz. Explore the pathogenesis, right-to-left shunting, PVR dynamics, and factors influencing PVR decline in neonates.

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