Persistent Pulmonary Hypertension (PPHN) Quiz
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Persistent Pulmonary Hypertension (PPHN) Quiz

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@ConsiderateAwareness

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Questions and Answers

What is the result of excessively high PVR in persistent pulmonary hypertension (PPHN)?

  • Persistence of the fetal circulatory pattern of right-to-left shunting through the PDA and foramen ovale after birth (correct)
  • Decreased pulmonary artery medial muscle thickness
  • Reduced postnatal PaO2 levels
  • Increased pulmonary hypoplasia
  • What is the consequence of lung inflation in reducing PVR?

  • Rapid decline in PVR (correct)
  • Release of vasoactive substances
  • Increase in PaCO2
  • Decrease in pH
  • What suggests right-to-left shunting through the ductus arteriosus in PPHN?

  • Decreased pH in the right radial artery
  • PaO2 or oxygen saturation gradient between a preductal and a post-ductal site of blood sampling (correct)
  • PaCO2 levels in the umbilical artery
  • Increased PVR in the pulmonary arterioles
  • What is the pathogenesis of PPHN related to chronic fetal hypoxia?

    <p>Increased pulmonary artery medial muscle thickness and extension of smooth muscle layers into the usually non-muscular, more peripheral pulmonary arterioles</p> Signup and view all the answers

    What diagnostic tool is helpful in evaluating PPHN?

    <p>2D echo with Doppler</p> Signup and view all the answers

    Study Notes

    Persistent Pulmonary Hypertension (PPHN)

    • Excessive PVR consequence: Right ventricular failure that may lead to cardiovascular collapse
    • Lung inflation effect: Reduces PVR by recruiting and distending lung vessels, improving oxygenation and cardiovascular stability

    Ductus Arteriosus Shunting

    • Right-to-left shunting indication: Presence of differential cyanosis (lower limbs more cyanosed than upper limbs)
    • Ductal shunting pathophysiology: Oxygenated blood from the aorta bypasses the lungs, deoxygenated blood from the pulmonary artery flows to the descending aorta

    PPHN Pathogenesis

    • Chronic fetal hypoxia effect: Increases pulmonary vascular resistance, leading to PPHN
    • Fetal hypoxia mechanisms: Impairs vascularization, increases smooth muscle growth, and alters vascular reactivity

    PPHN Diagnosis

    • Diagnostic tool: Echocardiography, which helps evaluate cardiac anatomy, right ventricular function, and pulmonary artery pressure

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    Description

    Test your knowledge of Persistent Pulmonary Hypertension (PPHN) with this quiz. Explore the pathogenesis, right-to-left shunting through PDA and foramen ovale, and factors influencing pulmonary vascular resistance.

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