Pernicious Anemia and Vitamin B12 Deficiency Quiz
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Questions and Answers

What is the normal range for Mean Cell Hemoglobin Concentration (MCHC) in adults?

  • 40-45 g/dL
  • 32-36 g/dL (correct)
  • 24-28 g/dL
  • 10-15 g/dL
  • Which type of anemia is associated with low Mean Cell Hemoglobin Concentration (MCHC)?

  • Iron-deficiency anemia (correct)
  • Sickle cell anemia
  • Megaloblastic anemia
  • Hemolytic anemia
  • What are the symptoms of anemia related to inadequate muscle function?

  • Abnormal cognitive development
  • Rapid heartbeat
  • Increased appetite
  • Decreased exercise tolerance (correct)
  • What is a characteristic symptom of anemia related to neurologic behavioral changes?

    <p>Anorexia</p> Signup and view all the answers

    Which nutrient deficiency is indicated by the presence of spoon-shaped nails (koilonychia)?

    <p>Iron deficiency</p> Signup and view all the answers

    When is oral iron supplements best absorbed according to the text?

    <p>When the stomach is empty</p> Signup and view all the answers

    What are some symptoms of pernicious anemia?

    <p>Numbness &amp; tingling in hands &amp; feet</p> Signup and view all the answers

    How is vitamin B12 deficiency diagnosed?

    <p>Serum holotranscobalamin I (holo TCH) &lt; 40 pg/mL</p> Signup and view all the answers

    What is the treatment for pernicious anemia?

    <p>Intramuscular injections of vitamin B12 once a month</p> Signup and view all the answers

    In pernicious anemia, where can vitamin B12 be stored in the body?

    <p>Liver</p> Signup and view all the answers

    When does anemia of chronic disease typically occur?

    <p>With inflammation, infection or malignancy</p> Signup and view all the answers

    What is the main process through which iron deficiency evolves in the body?

    <p>Cell division</p> Signup and view all the answers

    How do reticulocytes become mature red blood cells according to the text?

    <p>They cross from bone marrow to blood</p> Signup and view all the answers

    Which parameter has a negative feedback effect to control cell division in the context of iron deficiency?

    <p>Hemoglobin concentration</p> Signup and view all the answers

    What is a characteristic symptom of Fe deficiency anemia mentioned in the text?

    <p>Low Hemoglobin levels</p> Signup and view all the answers

    Which parameter is used to describe red blood cells in terms of individual cell size?

    <p>Mean Corpuscular Volume (MCV)</p> Signup and view all the answers

    What parameter can help in diagnosing iron deficiency and anemia according to the text?

    <p>Ferritin, iron, and transferrin evaluations</p> Signup and view all the answers

    Which mineral deficiency may occur with Zinc supplementation due to competition for binding sites on proteins?

    <p>Copper</p> Signup and view all the answers

    What type of anemia occurs at the initiation and early stages of a vigorous training program?

    <p>Sports anemia</p> Signup and view all the answers

    In laboratory data, what does a Serum B12 level of < 150 pg/ml indicate?

    <p>B12 deficiency</p> Signup and view all the answers

    What is the normal range for Hemoglobin in females?

    <p>&gt; 12 g/dl</p> Signup and view all the answers

    Which mineral increases the oxygen affinity of Red Blood Cells (RBCs)?

    <p>Zinc</p> Signup and view all the answers

    What does a Serum Folate level of < 3 ng/ml indicate according to laboratory data?

    <p>Deficiency</p> Signup and view all the answers

    What is the effect of inflammatory cytokines on iron absorption and erythroblast activity?

    <p>Decrease iron absorption and erythroblast activity</p> Signup and view all the answers

    What characterizes sickle cell disease in terms of hemoglobin genes inheritance?

    <p>Two abnormal hemoglobin genes, one from each parent</p> Signup and view all the answers

    What is a common symptom of sickle cell disease due to sickle-shaped RBCs getting caught in capillaries?

    <p>Episodes of severe acute abdominal pain</p> Signup and view all the answers

    Why is it important to differentiate sickle cell anemia from iron deficiency anemia?

    <p>To avoid excessive iron supplementation</p> Signup and view all the answers

    What is required for children and families affected by sickle cell anemia in terms of dietary intake during exacerbations?

    <p>Higher calorie intake</p> Signup and view all the answers

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