Peripheral Nerve Injury and Axon Regeneration Quiz
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Questions and Answers

Which cell type phagocytoses debris in an injured nerve fiber?

  • Schwann cells
  • Neurons
  • Macrophages (correct)
  • Muscle cells
  • What is the rate of axon growth during nerve fiber regeneration?

  • 1-2 mm/d
  • 0.5-3 mm/d (correct)
  • 0.1-0.5 mm/d
  • 3-5 mm/d
  • What happens to the muscle fiber in the weeks following nerve fiber injury?

  • It forms a compact cord
  • It proliferates
  • It degenerates
  • It becomes denervated (correct)
  • What is the main change that takes place in an injured nerve fiber?

    <p>The RER is greatly reduced initially</p> Signup and view all the answers

    What happens to the Schwann cells in the weeks following nerve fiber injury?

    <p>They form a compact cord penetrated by the regrowing axon</p> Signup and view all the answers

    What is the rate of nerve fiber regeneration?

    <p>1-2 mm/d</p> Signup and view all the answers

    Study Notes

    Phagocytosis of Debris in Injured Nerve Fibers

    • Macrophages are the primary cell type that phagocytoses debris in injured nerve fibers, helping in clean-up and recovery.

    Rate of Axon Growth During Regeneration

    • Axons grow at a rate of approximately 1 mm per day during the regeneration process, facilitating the repair of nerve damage.

    Changes in Muscle Fibers After Nerve Injury

    • Following nerve fiber injury, muscle fibers undergo atrophy and degeneration within the first few weeks due to loss of innervation.

    Main Changes in Injured Nerve Fibers

    • The main change in an injured nerve fiber is wallerian degeneration, where the axon distal to the injury site degenerates, prompting the regeneration process.

    Schwann Cells After Nerve Injury

    • Schwann cells proliferate and dedifferentiate in the weeks after nerve fiber injury, which supports axon regrowth and myelin sheath reconstruction.

    Overall Rate of Nerve Fiber Regeneration

    • The overall rate of nerve fiber regeneration can vary but is generally comparable to the axonal growth rate of about 1 mm per day, leading to functional recovery over time.

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    Description

    Test your knowledge on the changes that occur in an injured peripheral nerve and the potential for axon regeneration with this quiz. Keywords: peripheral nerve, axon regeneration, injury, RER.

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