Questions and Answers
What is the difference between a peptide and a protein?
Peptides are made up of linear amino acid chains.
Beta sheets adopt_______
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A protein can interact with water and lipds because__________
it has polar and hydrophobic amino acids.
The figure below shows a depiction of an antibody. Which label correctly identifies the region(s) of the antibody that contains variable amino acids for binding of a specific antigen?
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A glycoprotein ______.
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The first amino acid to be discovered was______________.
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Which of the following levels of protein structure involves the interaction of more than one protein into a multi-complex structure?
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Hydrogen bonding between NH and C=O groups of every 4th amino acid within the polypeptide backbone results in which type of folding pattern?
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The variable region on the surface of an antibody interacts specifically with an antigen through____.
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Which of the following represents secondary structures in a protein?
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Study Notes
Peptides and Proteins
- A peptide is a short chain of amino acids, whereas a protein is a long chain of amino acids.
Protein Structure
- Beta sheets adopt a pleated sheet conformation.
Protein Interactions
- A protein can interact with water and lipids because of its hydrophilic (water-loving) and hydrophobic (water-fearing) regions.
Antibody Structure
- The variable region of an antibody contains variable amino acids for binding of a specific antigen.
- The correct label for this region is the Fab (fragment, antigen-binding) region.
History of Amino Acid Discovery
- The first amino acid to be discovered was asparagine.
Protein-Protein Interactions
- Quaternary structure involves the interaction of more than one protein into a multi-complex structure.
Hydrogen Bonding and Folding
- Hydrogen bonding between NH and C=O groups of every 4th amino acid within the polypeptide backbone results in an alpha-helix folding pattern.
Antibody-Antigen Interactions
- The variable region on the surface of an antibody interacts specifically with an antigen through complementary shapes and chemical properties.
Secondary Structure
- Alpha helix and beta sheets represent secondary structures in a protein.
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