Peptic Ulcer Disease Quiz

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Questions and Answers

What is the first-line eradication therapy for H. pylori?

  • A 7-day course of dual-therapy with clarithromycin and a PPI
  • A 7-day course of triple-therapy with amoxicillin, clarithromycin/metronidazole, and a PPI (correct)
  • A 14-day course of quadruple-therapy with amoxicillin, clarithromycin, metronidazole, and a PPI
  • A 10-day course of dual-therapy with amoxicillin and a PPI

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Study Notes

  1. Peptic Ulcer Disease (PUD) is a lesion in the digestive tract caused by pepsin and stomach acid.
  2. PUD occurs mainly in the stomach or duodenum.
  3. There are two types of PUD: gastric and duodenal ulcers.
  4. Risk factors for PUD include smoking, acidic drinks, medications, H. pylori infection, age, gender, and genetic factors.
  5. PUD occurs when the balance between aggressive factors and mucosal defensive mechanisms are disrupted.
  6. H. pylori and NSAIDs are important factors in the formation of peptic ulcers.
  7. Symptoms of PUD include epigastric pain, dyspepsia, heartburn, haematemesis, melaena, and anaemia.
  8. Complications of PUD can include acute upper GI bleed or perforation.
  9. The definitive diagnosis of PUD is made on endoscopic examination.
  10. Management of PUD includes non-pharmacologic therapy, pharmacologic therapy, and surgical treatment.

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