Peptic Ulcer Disease: Pathophysiology and Management
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Questions and Answers

What is the typical location of Peptic Ulcer Disease?

  • Small intestine
  • Stomach and duodenum (correct)
  • Lower esophagus
  • All of the above

What is the primary cause of mucosal injury and peptic ulcer?

  • Consumption of acidic drinks
  • Infection by H pylori
  • Imbalance between gastric acid secretion and gastroduodenal mucosal defense (correct)
  • Smoking

What is the result of back diffusion of hydrogen ions?

  • Increased gastric acid secretion
  • Gastroduodenal mucosal defense strengthening
  • Epithelial cell injury (correct)
  • Epithelial cell repair

What is a lifestyle risk factor for Peptic Ulcer Disease?

<p>Smoking (D)</p> Signup and view all the answers

What is the effect of aggressive factors on the mucosal defense?

<p>Weakening of the mucosal defense (A)</p> Signup and view all the answers

What is the location of the ulcer in the majority of Peptic Ulcer Disease cases?

<p>Both stomach and duodenum (B)</p> Signup and view all the answers

What happens when an ulcer erodes through the entire wall of the stomach or duodenal wall?

<p>Perforation (B)</p> Signup and view all the answers

What is the principle of H.pylori eradication therapy?

<p>Reduce acid and pepsin secretion (D)</p> Signup and view all the answers

What is the indication for H.pylori eradication therapy?

<p>Both b and c (D)</p> Signup and view all the answers

What is the function of Prostaglandin Analogs in the management of peptic ulcers?

<p>Reduce gastric acid and enhance mucosal resistance to injury (B)</p> Signup and view all the answers

What is the treatment for narrowing and pyloric obstruction?

<p>Surgery (D)</p> Signup and view all the answers

What is the function of Antacids in the management of peptic ulcers?

<p>Neutralize acid and prevent pepsin formation (D)</p> Signup and view all the answers

What is the most common mode of transmission of Helicobacter pylori?

<p>Through fecal-oral route or oral-oral route (B)</p> Signup and view all the answers

At what age is the Duodenal peptic ulcer most commonly found?

<p>Between 30-40 years (D)</p> Signup and view all the answers

What is the term for the passage of black tarry stool?

<p>Melena (B)</p> Signup and view all the answers

What is the purpose of an esophagogastrodeuodenoscopy (EGD) in diagnosing peptic ulcers?

<p>All of the above (D)</p> Signup and view all the answers

What is the purpose of the Urea Breath Testing in diagnosing peptic ulcers?

<p>To detect H. pylori infection (D)</p> Signup and view all the answers

In which patients is endoscopy required?

<p>Those with dysphagia, weight loss, vomiting, or anorexia (D)</p> Signup and view all the answers

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