Peptic Ulcer Disease Overview
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Questions and Answers

What is the primary factor that affects the risk of PUD?

  • Consumption of carbonated beverages
  • Psychological stress
  • Amount smoked per day (correct)
  • Ingestion of ethanol in high concentrations
  • What is a characteristic of pain from duodenal ulcers?

  • It is usually worse after meals
  • It is often described as cramping
  • It often occurs at night
  • It is usually relieved by food (correct)
  • What is a symptom of gastric outlet obstruction?

  • Early satiety (correct)
  • Severe vomiting
  • Melena
  • Acute abdominal pain
  • What is a complication of PUD that may present as sudden, sharp, severe pain?

    <p>Perforation into the peritoneal cavity</p> Signup and view all the answers

    What is a characteristic of ulcers in older persons?

    <p>They may present with a “silent” ulcer complication</p> Signup and view all the answers

    What are the three common etiologies of peptic ulcer disease?

    <p>Helicobacter pylori infection, nonsteroidal anti-inflammatory drug (NSAID) use, and stress-related mucosal damage (SRMD)</p> Signup and view all the answers

    What is a significant difference in the acid secretion between duodenal ulcers and gastric ulcers?

    <p>Duodenal ulcers have normal acid secretion, whereas gastric ulcers have increased acid secretion.</p> Signup and view all the answers

    Which medication is primarily responsible for causing gastric mucosal damage by inhibiting endogenous mucosal PG synthesis?

    <p>Aspirin</p> Signup and view all the answers

    What impact does adding aspirin to a selective COX-2 inhibitor have on ulcer risk?

    <p>Increases the ulcer risk</p> Signup and view all the answers

    How is the ulcer risk affected when corticosteroids are used concomitantly with NSAIDs?

    <p>Ulcer risk increases</p> Signup and view all the answers

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