Podcast
Questions and Answers
What is the main reason that the addition of aspirin to a selective COX-2 inhibitor reduces its ulcer-sparing benefit and increases ulcer risk?
What is the main reason that the addition of aspirin to a selective COX-2 inhibitor reduces its ulcer-sparing benefit and increases ulcer risk?
- Aspirin and COX-2 inhibitors compete for the same metabolic pathways, leading to increased toxicity.
- Aspirin increases the absorption of the COX-2 inhibitor, leading to higher concentrations and more ulceration.
- Aspirin and COX-2 inhibitors have synergistic effects on gastric acid production, leading to more ulceration.
- Aspirin inhibits the production of prostaglandins, which are essential for maintaining gastric mucosal integrity. (correct)
According to the passage, which of the following statements about the use of corticosteroids and NSAIDs is correct?
According to the passage, which of the following statements about the use of corticosteroids and NSAIDs is correct?
- The use of corticosteroids alone increases the risk of ulcers and complications.
- The use of corticosteroids alone does not increase the risk of ulcers or complications.
- The use of corticosteroids and NSAIDs concurrently has no effect on the risk of ulcers.
- The use of corticosteroids and NSAIDs concurrently doubles the risk of ulcers. (correct)
Which of the following factors has been shown to cause peptic ulcer disease (PUD)?
Which of the following factors has been shown to cause peptic ulcer disease (PUD)?
- Consumption of coffee, tea, or beer
- Cigarette smoking (correct)
- Psychological stress
- Consumption of carbonated beverages
Which of the following is a common symptom of peptic ulcer disease?
Which of the following is a common symptom of peptic ulcer disease?
According to the passage, which of the following is a recommended test to verify the eradication of H. pylori infection?
According to the passage, which of the following is a recommended test to verify the eradication of H. pylori infection?
Which of the following is NOT a common etiology of peptic ulcer disease?
Which of the following is NOT a common etiology of peptic ulcer disease?
Which part of the duodenum is most commonly affected by duodenal ulcers?
Which part of the duodenum is most commonly affected by duodenal ulcers?
Which of the following is NOT involved in the pathophysiology of peptic ulcer disease?
Which of the following is NOT involved in the pathophysiology of peptic ulcer disease?
Which of the following statements about gastric ulcers and acid secretion is correct?
Which of the following statements about gastric ulcers and acid secretion is correct?
Which of the following statements about COX-2 selective inhibitors is correct?
Which of the following statements about COX-2 selective inhibitors is correct?
