18 Questions
Which type of penile neoplasm is characterized by sharply marginated, erythematous, scaly patch or plaque?
Bowen's Disease
What is a common risk factor for developing penile squamous cell carcinoma?
HPV infection
Which gene is affected in the pathogenesis of penile squamous cell carcinoma, leading to the degradation and inactivation of p53 and pRb?
E6
Which type of penile neoplasm is characterized by slow growth and may recur, with no P16 overexpression?
Verrucous Carcinoma
What is a common feature of the pathological findings of penile squamous cell carcinoma?
Prominent nucleoli
What is the most common treatment approach for penile squamous cell carcinoma?
Excision (partial/total penectomy), with or without inguinal lymph node dissection
What is a common serum marker seen in choriocarcinoma?
hCG
Which histological marker is typically negative in seminoma?
Cytokeratin
What is a possible genetic overrepresentation in seminoma?
KRAS
Which testicular germ cell tumor may present with sarcomatous components and negative PLAP?
Spermatocytic tumor
Which serum marker correlates with the overall tumor burden in testicular germ cell tumors?
Lactate dehydrogenase (LDH)
What is a characteristic pathologic feature of seminoma?
Uniform tumor cells with clear cytoplasm and prominent nucleoli
Which cells are responsible for initiating spermatogenesis in the testes?
Sertoli cells
What is the most common solid tumor in males aged 15-35?
Seminoma
Where do germ cell tumors usually spread hematogenously?
Supraclavicular nodes
What is the most common type of tumor in men aged 25-29 years?
Seminoma
Which risk factor is associated with an increased likelihood of developing testicular germ cell tumors?
Family history
What is the characteristic feature of teratoma tumors in adults?
Malignant behavior
Learn about penile and testicular tumors, including Penile Intraepithelial Neoplasia (PeIN) and Squamous Cell Carcinoma. Explore risk factors, HPV association, variants, and pathogenesis.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
