10 Questions
What percentage of patients have some kind of reaction to beta-lactam antibiotics?
5%
What is the primary cause of diarrhea associated with beta-lactam antibiotics?
Disruption of normal balance of intestinal microorganisms
What is a common cause of diarrhea after antibiotic use?
Pseudomembranous colitis
What is the term for swelling or inflammation of the large intestine due to an overgrowth of Clostridium difficile bacteria?
Pseudomembranous colitis
Why is methicillin no longer used clinically?
Due to its potential to cause acute interstitial nephritis
What is a potential side effect of injecting penicillins intrathecally?
Seizures
What is the term for a severe allergic reaction that can occur with beta-lactam antibiotics?
Anaphylaxis
What is the primary reason for determining a patient's history of allergic reactions to beta-lactam antibiotics?
To determine whether treatment with a beta-lactam is safe
What is the term for the marked swelling of the lips, tongue, and periorbital area?
Angioedema
Why do cross-allergic reactions occur among the beta-lactam antibiotics?
Due to their similar chemical structure
Learn how penicillins work to inhibit bacterial cell wall synthesis, leading to cell lysis. Understand the mechanism of action of these bactericidal antibiotics and their effectiveness.
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