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Questions and Answers

Which of the following antibiotics binds to the cell wall of bacteria?

  • Daptomycin
  • Fluoroquinolones
  • Trimethoprim
  • Vancomycin (correct)

Which type of bacteria has a thick peptidoglycan layer in its cell wall?

  • Gram-positive (correct)
  • Gram-negative
  • Atypical
  • All of the above

Which group of bacteria is coagulase-negative?

  • Listeria spp.
  • Enterococcus spp.
  • Staphylococcus spp. (correct)
  • Streptococcus spp.

Which of the following penicillins has the highest protein binding?

<p>Dicloxacillin (A)</p> Signup and view all the answers

Which penicillin has the highest bioavailability?

<p>Amoxicillin (A)</p> Signup and view all the answers

Which penicillin is primarily eliminated through feces?

<p>Nafcillin (A)</p> Signup and view all the answers

Which penicillin has the highest protein binding among the aminopenicillins?

<p>Ampicillin/Sulbactam (A)</p> Signup and view all the answers

Which generation of cephalosporins has the broadest activity against gram-positive aerobic bacteria?

<p>Fifth generation (D)</p> Signup and view all the answers

Which cephalosporin is the treatment of choice for Pseudomonas aeruginosa?

<p>Ceftolozane-tazobactam (D)</p> Signup and view all the answers

Which cephalosporin has the best coverage of methicillin-resistant Staphylococcus aureus (MRSA)?

<p>Cefiderocol (C)</p> Signup and view all the answers

Which cephalosporin has limited anaerobic activity?

<p>Ceftazidime-avibactam (D)</p> Signup and view all the answers

Which type of white blood cell is responsible for defense against bacteria and fungi?

<p>Neutrophils (B)</p> Signup and view all the answers

What is the major role of white blood cells (WBCs)?

<p>Defense against invading organisms (C)</p> Signup and view all the answers

What is the term for an increased number of immature neutrophils during an infection?

<p>Left shift (D)</p> Signup and view all the answers

Which type of white blood cell is responsible for defense against parasites and response against allergic reactions?

<p>Eosinophils (B)</p> Signup and view all the answers

Which of the following is a clinically significant gram-positive anaerobic bacteria?

<p>Clostridium spp. (D)</p> Signup and view all the answers

Which of the following is a clinically significant gram-negative aerobic bacteria?

<p>Pseudomonas aeruginosa (B)</p> Signup and view all the answers

Which of the following is a clinically significant gram-negative anaerobic bacteria?

<p>Bacteroides spp. (B)</p> Signup and view all the answers

Which class of beta-lactam antibiotics is divided into natural penicillins, penicillinase-resistant penicillins, aminopenicillins, and penicillin beta-lactamase inhibitor combinations?

<p>Penicillins (A)</p> Signup and view all the answers

Which class of antibiotics has the narrowest spectrum of activity?

<p>Natural Penicillins (C)</p> Signup and view all the answers

Which class of antibiotics is the gold standard for monomicrobial Methicillin-Susceptible Staphylococcus Aureus (MSSA) infections?

<p>Penicillinase-resistant penicillins (D)</p> Signup and view all the answers

Which generation of cephalosporins has excellent coverage of Streptococcus spp. and is the treatment of choice for methicillin-susceptible Staphylococcus aureus?

<p>First Generation (A)</p> Signup and view all the answers

Which generation of cephalosporins has the broadest gram-negative activity and extensive coverage of E. coli, K. pneumoniae, H. influenzae, and salmonella spp.?

<p>Fourth Generation (B)</p> Signup and view all the answers

Which of the following is NOT a characteristic of imipenem and meropenem?

<p>Extensive metabolism and elimination (D)</p> Signup and view all the answers

Which of the following is a side effect associated with imipenem, meropenem, and ertapenem?

<p>Seizures (B)</p> Signup and view all the answers

Which of the following is true about aztreonam?

<p>Has broad gram negative activity (B)</p> Signup and view all the answers

Which of the following is NOT a barrier to entry into the body?

<p>Respiratory tract (B)</p> Signup and view all the answers

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