Pediatrics Review Notes
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Questions and Answers

In the setting of local anesthetic systemic toxicity (LAST), what may be used intravenously?

Intralipid

Which diabetes medication can cause lactic acidosis in overdose?

  • Rosiglitazone (SGLT2i)
  • Insulin
  • Glyburide
  • Metformin (correct)
  • Acetaminophen overdose can lead to hepatotoxicity due to the formation of NAPQI. Activated charcoal should be given within _____ hours of ingestion.

    1-2 hours

    Iron overdose can lead to shock or liver failure.

    <p>True</p> Signup and view all the answers

    Match the following toxic alcohols with their associated antidotes:

    <p>Isopropyl alcohol = Supportive care Methanol = Fomepizole or ethanol Ethylene glycol = Fomepizole or ethanol</p> Signup and view all the answers

    What are some benefits of breastfeeding to the baby?

    <p>Immune protection</p> Signup and view all the answers

    Homogenized cow’s milk can be introduced to infants around 9-12 months.

    <p>True</p> Signup and view all the answers

    What is FPIES, and how is it treated?

    <p>FPIES is Food Protein-Induced Enterocolitis Syndrome. It is treated with fluids and ondansetron, while eliminating trigger foods.</p> Signup and view all the answers

    Kids exposed to too much screen time may experience early/severe __________.

    <p>constipation</p> Signup and view all the answers

    Match the following toxidromes with their symptoms and treatment:

    <p>Cholinergic Toxidrome = DUMBBELLS symptoms; Atropine, Pralidoxime treatment Anticholinergic Toxidrome = Confusion, hyperthermia, dry mouth symptoms; NaHCO3, Lorazepam treatment Sympathomimetic Toxidrome = Mydriasis, diaphoresis, HTN symptoms; Phentolamine, Lorazepam treatment Opioid Toxidrome = Bradycardia, respiratory depression, pinpoint pupils symptoms; Naloxone treatment</p> Signup and view all the answers

    Study Notes

    Breastfeeding

    • Benefits to mother: improved postpartum weight loss, delayed onset of menses, decreased breast and ovarian cancer risk, and cost-effectiveness
    • Benefits to baby: immune protection, cognitive development, decreased SIDS risk, and possibly decreased risk of diabetes, atopy, and acute lymphoblastic leukemia/acute myeloid leukemia
    • Composition: 20 kcal/oz (0.67 kcal/mL), high in IgA in colostrum, high in fat in hind milk, and 60:40 whey-to-casein ratio
    • Contraindications: mother with HIV, mother receiving cytotoxic chemotherapy or radiation, infant with galactosemia (PKU is not an absolute contraindication)
    • Recommendations: exclusive breastfeeding until 6 months, with 400 IU/day vitamin D, and continued breastfeeding along with solids until 2 years and beyond

    Infant Nutrition

    • First complementary foods should be iron-rich
    • Introduce lumpy textures no later than 9 months to avoid aversions
    • Responsive feeding: cue-based feeding, promote finger feeding, and open cups
    • Cow's milk-based, iron-fortified formula can be introduced around 9-12 months, with a maximum of 750 mL/24 oz daily
    • Avoid honey until 12 months due to botulism risk, and avoid added salt, sugar, and juice
    • Promote healthy eating habits with a regular schedule, and encourage parents to role-model healthy eating
    • For high-risk infants, introduce common allergens (e.g., peanuts, eggs) early (around 4-6 months), in appropriate textures, and maintain for tolerance

    Pediatric Growth, Obesity, and Screens

    • Use WHO growth curves
    • BMI categories: overweight (≥85th percentile), obesity (≥97th percentile), and severe obesity (≥99.9th percentile)
    • Obesity management: multi-disciplinary, with a focus on "5-2-1-0" rule (5+ fruits/veggies, ≤2 hours recreational screens, 1+ hour physical activity, and 0 sugar drinks)
    • Optimize sleep

    Allergy

    • Non-IgE food allergy (FPIES): profuse vomiting, pallor, lethargy, and hypotension within 1-4 hours of ingestion, with a peak incidence between 2-7 months
    • FPIAP (previously CMPA): intermittent mucous/bloody stools in otherwise well infants, with a strict elimination diet required for both baby and mother
    • Mastocytosis: rare condition with excessive mast cells, presenting with urtication and increased tryptase levels
    • Vaccine allergy: rare, but can occur with large local reactions
    • Allergic rhinitis: generally due to environmental allergies, with treatment involving antihistamines, nasal steroid sprays, and montelukast
    • Pollen-food allergy syndrome: localized IgE-mediated reaction, with no need for an EpiPen
    • Poison Ivy: type IV hypersensitivity reaction, with onset usually within 4-96 hours, and treatment involving high-potency topical steroids
    • Hereditary angioedema: episodic angioedema without itch or urticaria, with a high risk of airway compromise

    Toxicology

    • Four main toxidromes: cholinergic, anticholinergic, sympathomimetic, and opioid
    • Cholinergic toxidrome: DUMBBELLS (diaphoresis, urination, miosis, bronchorrhea, bradycardia, emesis, lacrimation, lethargy, salivation)
    • Anticholinergic toxidrome: "mad as a hatter, hot as a hare, blind as a bat, dry as a bone, red as a beet" (confusion, hyperthermia, mydriasis, dry mouth, urinary retention, flushed skin)
    • Sympathomimetic toxidrome: up and wet (mydriasis, diaphoresis, hypertension, tachycardia, hyperthermia, psychosis)
    • Opioid toxidrome: bradycardia, hypotension, respiratory depression, pinpoint pupils, coma
    • Decontamination: activated charcoal, intravenous lipids, and specific antidotes
    • Other toxins and toxicities: hydrocarbons, diabetes medications, acetaminophen, salicylates, iron, and cannabinoids

    Burns and Submersion Injuries

    • Submersion injuries: often preventable, with a higher risk in males, particularly in children under 9 years old
    • Burns: superficial partial thickness burns, with a focus on calculating the percentage of total body surface area (TBSA) affected
    • Electrical injuries: high-tension wires can cause extensive damage, with a risk of rhabdomyolysis, CNS injuries, and fatal arrhythmias
    • Inhalational injuries: suspect in the setting of singed nasal hairs, soot in the airway, and hoarseness, with a risk of CO, CN-, and HCl poisoning

    Child Maltreatment

    • Risk factors: having a caregiver who is a victim of intimate partner violence, as well as other child-specific, caregiver-specific, and household-specific factors
    • Child maltreatment and adverse childhood experiences (ACEs) predispose to worse health outcomes
    • Physical examination in cases of sexual abuse is often normal or nonspecific
    • Hymenal injuries: hymenal notches can be normal if above 3 and 9 o'clock or below these positions, but without extending to the base of the hymen

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    Description

    Review notes for pediatrics, covering high-yield pearls and information retention tips. Sources include CPRP 2023 and CPS position statements.

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