Pediatrics Paper 2 - 2024 June

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Questions and Answers

Which condition is associated with the highest risk of adverse outcomes from infective endocarditis (IE)?

  • Prosthetic cardiac valve (correct)
  • Previous episodes of pneumonia
  • Uncontrolled diabetes mellitus
  • Controlled hypertension

What is the most common causative organism of endocarditis linked to dental and oral procedures?

  • Staphylococcus aureus
  • Enterococcus faecalis
  • Streptococcus viridans (correct)
  • Pseudomonas aeruginosa

What is the recommended standard prophylactic regimen for endocarditis?

  • Continuous intravenous line of vancomycin
  • A single dose of oral clindamycin
  • Two doses of oral azithromycin
  • A single dose of oral amoxicillin (correct)

Which of the following patients is NOT considered at high risk for developing infective endocarditis?

<p>A patient with a prosthetic limb (B)</p> Signup and view all the answers

Which congenital heart defect requires careful consideration in the context of endocarditis prophylaxis?

<p>Unrepaired cyanotic congenital heart disease (A)</p> Signup and view all the answers

In the context of endocarditis, which device placement requires prophylaxis consideration during the first six months?

<p>Left atrial appendage occlusion device (C)</p> Signup and view all the answers

Which drug is typically included in the pharmacological treatment for ventricular fibrillation when epinephrine is ineffective?

<p>Amiodarone 300 mg (A)</p> Signup and view all the answers

What is the primary goal of antibiotic regimens for endocarditis prophylaxis?

<p>To direct treatment toward Streptococcus viridans (A)</p> Signup and view all the answers

What is the primary route of administration for adrenaline in a pediatric emergency setting?

<p>Intravenous/ Intraosseous (D)</p> Signup and view all the answers

What is the correct initial dose of adrenaline for a child in an emergency situation?

<p>10 mcg/kg (D)</p> Signup and view all the answers

Which medication is recommended for rate control in a patient with atrial fibrillation after initial treatment?

<p>Bisoprolol (B)</p> Signup and view all the answers

If a patient has a DVT with low hemoglobin and ferritin, which follow-up investigation is suggested next?

<p>Colonoscopy (B)</p> Signup and view all the answers

In a patient presenting with erythematous and swollen leg lesions post insect bite, what is the best antibiotic choice?

<p>Cefuroxime (D)</p> Signup and view all the answers

What antihyperglycemic medication should be added to a patient's regimen if they have a high HbA1C while on metformin and sitagliptin?

<p>Empagliflozin (C)</p> Signup and view all the answers

Which condition is associated with pyoderma gangrenosum?

<p>Crohn's disease (B)</p> Signup and view all the answers

What is the maximum single dose of adrenaline that can be administered to a pediatric patient?

<p>1 mg (C)</p> Signup and view all the answers

What is the recommended prophylaxis for a man with a known bicuspid aortic valve and mitral valve regurgitation before a dental procedure?

<p>No prophylaxis (C)</p> Signup and view all the answers

Which of the following conditions would require antibiotic prophylaxis for infective endocarditis before a dental procedure?

<p>Previous history of infective endocarditis (A)</p> Signup and view all the answers

What is true regarding antibiotic prophylaxis for dental procedures?

<p>Patients with congenital heart conditions may require prophylaxis (B)</p> Signup and view all the answers

Which of the following statements about infective endocarditis prophylaxis is accurate?

<p>Patients with implanted cardiac devices require prophylaxis based on risk (B)</p> Signup and view all the answers

Why is there no prophylaxis necessary for the man with a bicuspid aortic valve and mitral regurgitation?

<p>He is asymptomatic and no complications are present. (B)</p> Signup and view all the answers

Which type of heart valve condition typically requires antibiotic prophylaxis during dental procedures?

<p>History of rheumatic fever with valve damage (A)</p> Signup and view all the answers

Which component is considered when assessing the necessity for antibiotic prophylaxis before dental work?

<p>Presence of congenital heart disease (D)</p> Signup and view all the answers

What type of antibiotic therapy is typically not indicated for prophylaxis in dental procedures?

<p>Doxycycline (C)</p> Signup and view all the answers

Flashcards

Congenital Rubella complication (not)

Large for gestational age is not a complication of congenital rubella.

ASD murmur ECG finding

A secundum atrial septal defect (ASD) is associated with right axis deviation on ECG.

Bilateral suppurative conjunctivitis complication

Meningoencephalitis is a possible complication of bilateral suppurative conjunctivitis.

Hand, foot, and mouth disease cause

Coxsackie A virus is the common cause of hand, foot, and mouth disease, characterized by blisters/sores in the mouth and on hands/feet.

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Lead poisoning symptoms in children

Lead poisoning in children can present with altered mental status and syncope, along with distal motor neuropathy.

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HbSS disease stroke treatment

Urgent exchange transfusion is the most definitive treatment for a stroke in patients with HbSS disease (sickle cell disease).

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Primary amenorrhea cause (14yo girl)

Turner syndrome (45,X karyotype) is a possible cause of primary amenorrhea in a girl who is short for her age and has delayed puberty.

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Coffee ground vomit cause

Swallowed blood, originating from cracked nipples, is a possible cause of coffee ground vomitus in a healthy infant.

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Asthma treatment escalation (ICS)

In a child with asthma already on inhaled corticosteroids (ICS) who is now using their rescue inhaler (SABA) daily, adding a long-acting bronchodilator (LABA) is usually the next logical step, rather than increasing ICS.

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Bipolar 1

Characterized by a manic episode lasting more than a week, without a depressive episode, and increased energy, euphoria, and rapid speech.

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Bipolar 2

Involves hypomanic episodes (4 days) followed by a depressive episode, often feeling hopeless and irritable.

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Schizophreniform Disorder

Similar symptoms as schizophrenic, lasting 1 month but less than 6 months.

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MDD (Major Depressive Disorder)

Depressive episodes separated by at least 2 months.

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Cyclothymic Disorder

Experiences hypomania and mild depression for at least two years, with periods of euthymia lasting less than 8 weeks.

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Narcissistic Personality Disorder

Characterized by delusions of grandiosity, egotism, and a lack of empathy.

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Infective Endocarditis Prophylaxis

Antibiotic prophylaxis is warranted for patients with high-risk conditions or implanted devices if IE occurs.

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Major Neurocognitive Disorder (Dementia)

A condition marked by decreased mental function and loss of daily task abilities.

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Adrenaline IV/IO dose (children)

10 mcg/kg (0.1 mL/kg of 1 in 10,000 solution).

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Adrenaline Subsequent Doses

Every 3-5 minutes.

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Epinephrine Dose (non-shockable rhythm)

0.01 mg/kg (max 1 mg) followed by every 3–5 minutes.

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Erythematous leg lesion (non-purulent)

Red, swollen, but not pus-filled leg lesion likely due to infection.

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Best abx for erythematous leg lesion (non-purulent, HIV/DM)

Cefuroxime (likely).

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Acute Dyspnea

Sudden breathlessness, often a serious medical condition.

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Irregularly irregular pulse

Heart rate inconsistent and not in a regular pattern.

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Atrial fibrillation (AF)

Rapid, irregular heart rhythm originating from the atria.

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Best med for acute AF (rate control)

Bisoprolol (beta-blocker).

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DVT

Blood clot in a deep vein (usually in the leg).

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Cause of low Hb, low MCV, low ferritin with DVT

Likely iron deficiency anaemia, possibly related.

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Next Investigation for low Hb, low MCV, low ferritin with suspected DVT

Colonoscopy (to rule out internal bleeding).

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Pyoderma gangrenosum ulcers

Skin ulcers that are painful, often in association with other conditions.

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Associated condition with pyoderma gangrenosum ulcers

Crohn's Disease (likely).

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Hyperglycemia on metformin, sitagliptin

High blood sugar levels despite taking metformin and sitagliptin.

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Antihyperglycemic to add to metformin, sitagliptin with hyperglycemia

Empagliflozin (SGLT2 inhibitor).

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High-risk IE conditions

Conditions associated with a higher chance of developing infective endocarditis (IE), a serious infection of the heart valves.

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Prosthetic heart valves

Artificial heart valves increasing IE risk.

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Cardiac valve repair (prosthetic)

Repairing heart valves with artificial material, increasing the chance of IE.

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Durable mechanical circulatory devices

Heart assist devices (e.g., ventricular assist devices) making IE possible.

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Previous IE

Having infective endocarditis before increases the risk of getting it again.

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Certain congenital heart diseases

Specific birth defects which are risk factors for IE, mainly due to damage to heart structures.

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Unrepaired cyanotic heart disease

Heart condition present at birth that limits oxygen and increases IE risk.

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Repaired congenital heart defect (within 6 months)

Surgery performed in the first six months after heart defect repair incurs IE risk.

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Residual defects after heart repair

Incomplete repair leading to possible IE complications.

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Prosthetic pulmonary artery valves

Artificial pulmonary artery valves causing increased risk for IE.

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Cardiac transplant recipients

Individuals with a transplanted heart are at a higher risk for valvulopathy, a condition that makes the valves of the heart weaker, increasing their vulnerability to IE.

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Left atrial appendage occlusion devices

Implanted devices placed in the left atrial appendage in the first six months of implantation increase risk of IE.

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Common cause of IE for dental procedures

S. viridans (alpha-hemolytic streptococci) is the common bacteria responsible for IE following oral procedures.

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Standard IE prophylaxis

A single dose of oral amoxicillin is recommended for this bacteria prevention.

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Isoniazid side effect

Isoniazid, a TB drug, can lead to numbness and paraesthesia; problems with feeling.

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Adrenaline dosage (VF adult)

Incorrect dosage; 1 mg, not 0.1 mg, is a corrected dose for adult cardiac arrest in ventricular fibrillation.

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Pulseless VT treatment

The treatment for Ventricular Tachycardia (VT) without a pulse usually involves Defibrillation (shock) and IV vasopressors/antiarrhythmics like epinephrine.

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Study Notes

Pediatrics (Paper 2 - 2024 June)

  • Congenital rubella is a complication of mother having acute infection during pregnancy.
  • Major complications include intrauterine growth retardation, hepatosplenomegaly, cataracts, mental retardation, sensorineural hearing loss, heart abnormalities (PDA, pulmonary stenosis), and thrombocytopenic purpura.
  • Large for gestational age is not a complication of congenital rubella.
  • Right axis deviation is expected on an ECG for a secundum atrial septal defect (ASD).
  • ASD's types include: ostium secundum, sinus venosus, and ostium primum.
  • Kawasaki disease diagnostic criteria include fever for five days and four of five clinical features: changes in the oral cavity and lips, polymorhpous rash, bilateral conjunctivitis, changes in the extremities & cervical lymphadenopathy.
  • In Kawasaki disease, generalized lymphadenopathy is less than 2cm.
  • Proteinuria is important for determining long-term prognosis of HSP.
  • Clinical features of HSP include rash, joint pain (arthritis), abdominal pain, and kidney impairment.
  • Henoch-Schönlein purpura (HSP) involves rash, palpable purpura, symmetric appearance, and, often, arthritis in 75% of cases.
  • Treatment for HSP includes NSAIDs and, in severe cases, steroids, dapsone, or colchicine, with IV immunoglobulins if needed, along with immunosuppressive medications.
  • A 8-year-old child with a generalized tonic-clonic seizure and an unarousable state following seizure and a chest/limb rash, suggests meningoencephalitis.
  • Simple febrile seizure lasts less than 15 minutes.
  • Complex febrile seizures last more than 15 minutes, occur more than once in 24 hours, and are often associated previously diagnosed seizure problems.
  • A 2 year old child with sores on the hands and feet most likely has scabies.
  • Scabies is an infestation caused by mites. Typical symptoms of scabies include sores, bumps, and scabs in the finger and wrist area.
  • Coxsackie A viral infection can cause a rash on hands and feet.

Other topics (Paper 2 - 2024 June)

  • A 12-year-old boy exhibiting disruptive behavior in school, possibly due to lead poisoning, may present with altered mental status and syncope.
  • Elevated lead levels may be associated with distal motor neuropathy (wrist/foot drop).
  • Kawasaki disease is characterized by fever and rash, requiring treatment with high-dose IV immunoglobulin and aspirin.
  • A 14-year-old girl experiencing delayed puberty and short stature may have Turner syndrome.
  • Vomiting blood (coffee-ground emesis) in an infant, without other significant symptoms or complications, might be caused by swallowed blood from cracked nipples.
  • Symptoms of a Mallory-Weiss tear include profuse vomiting and forceful retching, often presenting with upper gastrointestinal bleeding.
  • Boerhaave syndrome, or esophageal rupture, is characterized by chest pain, vomiting, subcutemaneous emphysema.
  • Elevated serum ACEs and bilateral hilar adenopathy in a 2-year-old are likely suggestive of sarcoidosis.
  • A 1 week old baby with vomiting blood (coffee-ground emesis) and normal physical exam or blood tests. is likely caused by blood swallowed from cracked nipples.

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