Pediatric Bone Health and Vitamin D Screening
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Questions and Answers

The test most likely to provide information useful in addressing this patient’s concern is a serum total 25-hydroxyvitamin D level (25-OH- ______).

D

The 2014 American Academy of Pediatrics (AAP) clinical report recommends vitamin D screening for those with conditions associated with low bone mass or multiple low-impact ______.

fractures

Stress fractures occur when recovery and nutritional support are inadequate to heal the bony ______ that occurs during high-intensity physical activity.

microtrauma

Preventing stress fractures requires assessment and management of issues that increase ______ development or decrease the body’s capacity for bony recovery.

<p>microtrauma</p> Signup and view all the answers

Maintaining sufficient calorie intake is essential to support good ______ function in female athletes.

<p>menstrual</p> Signup and view all the answers

It is important to recognize that these levels are based on a goal of avoidance of nutritional ______, and do not necessarily represent optimal levels for bone health.

<p>rickets</p> Signup and view all the answers

Osteoclasts are activated and calcium bioavailability is decreased when 25-OH-D levels are less than ______ ng/mL.

<p>30</p> Signup and view all the answers

The current recommendation for athletes to minimize injury risk and optimize athletic performance is to maintain 25-OH-D levels between ______ and 50 ng/mL.

<p>32</p> Signup and view all the answers

Many adolescents are not maintaining adequate vitamin ______ levels.

<p>D</p> Signup and view all the answers

Cross-sectional studies have found 25-OH-D deficiency rates between ______% and 47%.

<p>17</p> Signup and view all the answers

Certain subpopulations at risk for deficiency include those with dark skin ______.

<p>pigmentation</p> Signup and view all the answers

Screening radiography does not have a role in looking for bone stress injury in ______ children.

<p>asymptomatic</p> Signup and view all the answers

Magnetic resonance imaging (MRI) is more sensitive than radiography for detecting stress ______ and reactions.

<p>fractures</p> Signup and view all the answers

The specific role of stress fractures in determining the need for ______ is not clearly delineated.

<p>densitometry</p> Signup and view all the answers

The triad is defined as caloric intake that is insufficient to support healthy physiologic function and energy needs of ______.

<p>training</p> Signup and view all the answers

Some athletes with inadequate energy availability suppress physiologic function even though body weight is ______.

<p>maintained</p> Signup and view all the answers

Study Notes

Vitamin D Screening and Recommendations

  • Serum total 25-hydroxyvitamin D level (25-OH-D) is crucial for assessing vitamin D status, especially in children with low bone mass or multiple low-impact fractures.
  • AAP recommends vitamin D screening for high-risk children, including athletes with stress fractures.
  • Adequate serum levels of 25-OH-D are debated, with a 2016 consensus suggesting:
    • Deficiency: <50 nmol/L
    • Insufficiency: 50-75 nmol/L
    • Sufficient: >75 nmol/L

Stress Fractures in Athletes

  • Stress fractures occur when recovery and nutrition are insufficient during intense physical activity.
  • Prevention requires:
    • Gradual training increase to avoid microtrauma.
    • 36 to 48 hours of rest or light workouts post-hard sessions.
    • Sufficient caloric intake to support menstrual function and estrogen levels.
    • Adequate vitamin D and calcium intake.
  • Levels less than 30 ng/mL (74 nmol/L) decrease calcium bioavailability and activate osteoclasts.
  • In athletes and military personnel, stress fracture rates drop when 25-OH-D levels are ≥30 ng/mL.
  • Current recommendations for athletes suggest maintaining 25-OH-D levels between 32-50 ng/mL (80-125 nmol/L).

Vitamin D Deficiency in Adolescents

  • 25-OH-D deficiency among adolescents ranges from 17% to 47%.
  • At-risk groups include:
    • Individuals living north of the 35th parallel.
    • Those minimizing UVB exposure via clothing/sunscreen.
    • Individuals with dark skin pigmentation.
    • Overweight or obese adolescents.
    • Indoor training athletes such as dancers and gymnasts.

Imaging and Bone Health Assessments

  • Screening radiography is not useful for detecting asymptomatic bone stress injuries in children.
  • MRI is more sensitive for detecting stress fractures but may lead to overdiagnosis in asymptomatic athletes.
  • Bone densitometry recommendations by the AAP apply to:
    • Children with ≥2 long bone fractures before age 10.
    • Children with ≥3 long bone fractures before age 19.
    • Individuals with vertebral fractures without significant trauma.

Female Athlete Triad

  • Defined as a combination of insufficient caloric intake for training, menstrual dysfunction, and bone mineral density loss.
  • Athletes can experience the triad with low body weight or maintained weight but inadequate energy availability.
  • Recognition of stress fractures in young female athletes raises concerns for this triad, indicating the need for further assessment and management.

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Description

This quiz focuses on the importance of serum total 25-hydroxyvitamin D levels in children and adolescents. It discusses guidelines from the American Academy of Pediatrics regarding vitamin D screening for those at risk of low bone mass and stress fractures. Test your knowledge on pediatric bone health and the critical role of vitamin D.

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