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Questions and Answers
What is the first step in vitamin D synthesis?
What is the first step in vitamin D synthesis?
- Conversion to calcitriol
- Conversion to calcidiol
- Sunlight contacting the epidermis (correct)
- Transport to the liver
What happens to cholecalciferol in step two?
What happens to cholecalciferol in step two?
It is converted to calcidiol in the liver.
What is the role of calcidiol in step three?
What is the role of calcidiol in step three?
It returns to the blood for transport to the kidneys.
In step four, Calcitriol acts on three target organs: The small intestine, skeleton, and the _____
In step four, Calcitriol acts on three target organs: The small intestine, skeleton, and the _____
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Calcitriol is the active form of vitamin D that increases blood calcium.
Calcitriol is the active form of vitamin D that increases blood calcium.
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Study Notes
Vitamin D Synthesis Steps
- Sunlight exposure triggers the conversion of seven dehydrocholesterol in the epidermis to vitamin D3 (cholecalciferol).
- Cholecalciferol is transported to the liver through the bloodstream, where it is metabolized to calcidiol.
- Calcidiol circulates back into the bloodstream and is transported to the kidneys for final conversion into calcitriol.
- Calcitriol, the most active form of vitamin D, enhances blood calcium levels by influencing three key target organs: the small intestine, bones (skeleton), and kidneys.
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