40 Questions
Fusions between FGFR1 and various fusion partners occur in a small percentage of ______ cancers
lung
Carcinoid tumors in the lungs are characterized by the expression of neuroendocrine markers such as ______
chromogranin
Mesothelioma, a type of cancer affecting the lining of the lungs, is strongly associated with exposure to ______ fibers
asbestos
Intratumor heterogeneity, the presence of different genetic mutations within the same tumor, is a significant challenge in treating ______ cancers
lung
Mesothelioma is commonly linked to mutations in the ______ gene
BAP1
Amplification of FGFR1 is found in 20% of squamous cell carcinomas and can lead to intratumor ______
heterogeneity
Lung carcinoids account for 2-3% of all lung cancers and develop in ______ cells of the normal bronchial epithelium
neuroendocrine
Carcinoid tumors in the lung have two subtypes: typical carcinoid and atypical ______
carcinoid
Mesothelioma, a cancer of the pleural lining, is most often caused by exposure to ______
asbestos
Patients with typical carcinoids have a 90% 5-year survival after surgery, while those with atypical carcinoids have a 60% 5-year survival due to their ______ growth
slow
FGFR1 mutations are commonly found in _______ cancers
lung
_______ tumors in lungs are known for their slow-growing nature
Carcinoid
Exposure to asbestos is a risk factor for developing _______ in lungs
Mesothelioma
Intratumor heterogeneity is a challenge in treating _______ cancers
lung
_______ exposure is associated with 10% of lung cancers
Radon
Carcinoid tumors in lungs are characterized by the presence of ______ cells
neuroendocrine
Mesothelioma in lungs is primarily caused by exposure to ______
asbestos
FGFR1 in lung cancers is a potential therapeutic target due to its role in promoting cancer cell ______
proliferation
Intratumor heterogeneity in lung cancers refers to the presence of different genetic mutations within the same ______
tumor
The staging system for lung carcinoma includes T: tumor size, N: spread of tumor to lymph nodes, and M: presence of distant ______
metastases
Fusions between FGFR1 and various fusion partners occur in a small percentage of ______ cancers
lung
Carcinoid tumors in the lungs are characterized by the expression of neuroendocrine markers such as ______
neuroendocrine
Mesothelioma, a type of cancer affecting the lining of the lungs, is strongly associated with exposure to ______ fibers
asbestos
Intratumor heterogeneity, the presence of different genetic mutations within the same tumor, is a significant challenge in treating ______ cancers
lung
Mesothelioma is commonly linked to mutations in the ______ gene
BAP1
Fusions between FGFR1 and various fusion partners occur in a small percentage of ______ cancers
lung
Mesothelioma is commonly linked to mutations in the ______ gene
FGFR1
Mesothelioma, a type of cancer affecting the lining of the lungs, is strongly associated with exposure to ______ fibers
asbestos
Intratumor heterogeneity, the presence of different genetic mutations within the same tumor, is a significant challenge in treating ______ cancers
lung
Carcinoid tumors in the lungs are characterized by the expression of neuroendocrine markers such as ______
chromogranin
Peripheral tumors are more likely to be discovered on routine chest radiographs or after they have become quite advanced due to their location ______
outside
Features of Pancoast Tumours may cause specific symptoms due to their location in the ______
upper
Tumours involving the nerves of the brachial plexus can cause nerve entrapment syndromes like Horner’s syndrome if the tumour impinges the sympathetic nerve plexus it can lead to Horner’s syndrome on the ______ side
ipsilateral
Shoulder and upper back pain are common symptoms of Pancoast Tumours as they often impact the ribs and/or ______
spine
Cough is reported to be the most common presenting symptom of lung cancer due to the primary tumour itself, locoregional spread, distant metastatic disease, and ectopic hormone production like ______ syndromes
paraneoplastic
FGFR1 in lung cancers: Treatment is largely ineffective, and prognosis is poor. Few patients survive longer than 18 months after diagnosis. Lung metastases may not cause any symptoms initially. The symptoms will vary depending on the number of tumours and their location in the lungs. Almost any cancer can metastasize to the lung, but some are more common to do so, including: Bladder cancer, Breast cancer, Colorectal cancer, Kidney cancer, Melanoma, Sarcomas, and ______.
Testicular
Carcinoid tumors in lungs: Treatment is largely ineffective, and prognosis is poor. Few patients survive longer than 18 months after diagnosis. Lung metastases may not cause any symptoms initially. The symptoms will vary depending on the number of tumours and their location in the lungs. Almost any cancer can metastasize to the lung, but some are more common to do so, including: Bladder cancer, Breast cancer, Colorectal cancer, Kidney cancer, Melanoma, Sarcomas, and ______.
Testicular
Mesothelioma in lungs: Treatment is largely ineffective, and prognosis is poor. Few patients survive longer than 18 months after diagnosis. Lung metastases may not cause any symptoms initially. The symptoms will vary depending on the number of tumours and their location in the lungs. Almost any cancer can metastasize to the lung, but some are more common to do so, including: Bladder cancer, Breast cancer, Colorectal cancer, Kidney cancer, Melanoma, Sarcomas, and ______.
Testicular
Intratumor heterogeneity in lung cancers: Treatment is largely ineffective, and prognosis is poor. Few patients survive longer than 18 months after diagnosis. Lung metastases may not cause any symptoms initially. The symptoms will vary depending on the number of tumours and their location in the lungs. Almost any cancer can metastasize to the lung, but some are more common to do so, including: Bladder cancer, Breast cancer, Colorectal cancer, Kidney cancer, Melanoma, Sarcomas, and ______.
Testicular
Lung metastases: The lungs are a common site of metastasis of other cancers via the lymphatic system or the bloodstream. Cancers can spread to any location in the lungs, but most metastatic cancers develop near the edges of the lungs and in the lower lobes. There can be a single metastasis in one lung or many metastases in one or both lungs. Lung metastases may not cause any symptoms initially. The symptoms will vary depending on the number of tumours and their location in the lungs. Almost any cancer can metastasize to the lung, but some are more common to do so, including: Bladder cancer, Breast cancer, Colorectal cancer, Kidney cancer, Melanoma, Sarcomas, and ______.
Testicular
Test your knowledge on the pathogenesis, clinical features, and complications/prognosis of lung neoplasms such as Adenocarcinoma, squamous cell carcinoma, large cell carcinoma, small cell carcinoma, and carcinoid. Also, compare the characteristics of metastatic lung cancer to primary lung cancer and learn about the common pathophysiology of lung diseases.
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