Lung Cancer AI Quiz Short Answer BMS 250
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Questions and Answers

Fusions between FGFR1 and various fusion partners occur in a small percentage of ______ cancers

lung

Carcinoid tumors in the lungs are characterized by the expression of neuroendocrine markers such as ______

chromogranin

Mesothelioma, a type of cancer affecting the lining of the lungs, is strongly associated with exposure to ______ fibers

asbestos

Intratumor heterogeneity, the presence of different genetic mutations within the same tumor, is a significant challenge in treating ______ cancers

<p>lung</p> Signup and view all the answers

Mesothelioma is commonly linked to mutations in the ______ gene

<p>BAP1</p> Signup and view all the answers

Amplification of FGFR1 is found in 20% of squamous cell carcinomas and can lead to intratumor ______

<p>heterogeneity</p> Signup and view all the answers

Lung carcinoids account for 2-3% of all lung cancers and develop in ______ cells of the normal bronchial epithelium

<p>neuroendocrine</p> Signup and view all the answers

Carcinoid tumors in the lung have two subtypes: typical carcinoid and atypical ______

<p>carcinoid</p> Signup and view all the answers

Mesothelioma, a cancer of the pleural lining, is most often caused by exposure to ______

<p>asbestos</p> Signup and view all the answers

Patients with typical carcinoids have a 90% 5-year survival after surgery, while those with atypical carcinoids have a 60% 5-year survival due to their ______ growth

<p>slow</p> Signup and view all the answers

FGFR1 mutations are commonly found in _______ cancers

<p>lung</p> Signup and view all the answers

_______ tumors in lungs are known for their slow-growing nature

<p>Carcinoid</p> Signup and view all the answers

Exposure to asbestos is a risk factor for developing _______ in lungs

<p>Mesothelioma</p> Signup and view all the answers

Intratumor heterogeneity is a challenge in treating _______ cancers

<p>lung</p> Signup and view all the answers

_______ exposure is associated with 10% of lung cancers

<p>Radon</p> Signup and view all the answers

Carcinoid tumors in lungs are characterized by the presence of ______ cells

<p>neuroendocrine</p> Signup and view all the answers

Mesothelioma in lungs is primarily caused by exposure to ______

<p>asbestos</p> Signup and view all the answers

FGFR1 in lung cancers is a potential therapeutic target due to its role in promoting cancer cell ______

<p>proliferation</p> Signup and view all the answers

Intratumor heterogeneity in lung cancers refers to the presence of different genetic mutations within the same ______

<p>tumor</p> Signup and view all the answers

The staging system for lung carcinoma includes T: tumor size, N: spread of tumor to lymph nodes, and M: presence of distant ______

<p>metastases</p> Signup and view all the answers

Fusions between FGFR1 and various fusion partners occur in a small percentage of ______ cancers

<p>lung</p> Signup and view all the answers

Carcinoid tumors in the lungs are characterized by the expression of neuroendocrine markers such as ______

<p>neuroendocrine</p> Signup and view all the answers

Mesothelioma, a type of cancer affecting the lining of the lungs, is strongly associated with exposure to ______ fibers

<p>asbestos</p> Signup and view all the answers

Intratumor heterogeneity, the presence of different genetic mutations within the same tumor, is a significant challenge in treating ______ cancers

<p>lung</p> Signup and view all the answers

Mesothelioma is commonly linked to mutations in the ______ gene

<p>BAP1</p> Signup and view all the answers

Fusions between FGFR1 and various fusion partners occur in a small percentage of ______ cancers

<p>lung</p> Signup and view all the answers

Mesothelioma is commonly linked to mutations in the ______ gene

<p>FGFR1</p> Signup and view all the answers

Mesothelioma, a type of cancer affecting the lining of the lungs, is strongly associated with exposure to ______ fibers

<p>asbestos</p> Signup and view all the answers

Intratumor heterogeneity, the presence of different genetic mutations within the same tumor, is a significant challenge in treating ______ cancers

<p>lung</p> Signup and view all the answers

Carcinoid tumors in the lungs are characterized by the expression of neuroendocrine markers such as ______

<p>chromogranin</p> Signup and view all the answers

Peripheral tumors are more likely to be discovered on routine chest radiographs or after they have become quite advanced due to their location ______

<p>outside</p> Signup and view all the answers

Features of Pancoast Tumours may cause specific symptoms due to their location in the ______

<p>upper</p> Signup and view all the answers

Tumours involving the nerves of the brachial plexus can cause nerve entrapment syndromes like Horner’s syndrome if the tumour impinges the sympathetic nerve plexus it can lead to Horner’s syndrome on the ______ side

<p>ipsilateral</p> Signup and view all the answers

Shoulder and upper back pain are common symptoms of Pancoast Tumours as they often impact the ribs and/or ______

<p>spine</p> Signup and view all the answers

Cough is reported to be the most common presenting symptom of lung cancer due to the primary tumour itself, locoregional spread, distant metastatic disease, and ectopic hormone production like ______ syndromes

<p>paraneoplastic</p> Signup and view all the answers

FGFR1 in lung cancers: Treatment is largely ineffective, and prognosis is poor. Few patients survive longer than 18 months after diagnosis. Lung metastases may not cause any symptoms initially. The symptoms will vary depending on the number of tumours and their location in the lungs. Almost any cancer can metastasize to the lung, but some are more common to do so, including: Bladder cancer, Breast cancer, Colorectal cancer, Kidney cancer, Melanoma, Sarcomas, and ______.

<p>Testicular</p> Signup and view all the answers

Carcinoid tumors in lungs: Treatment is largely ineffective, and prognosis is poor. Few patients survive longer than 18 months after diagnosis. Lung metastases may not cause any symptoms initially. The symptoms will vary depending on the number of tumours and their location in the lungs. Almost any cancer can metastasize to the lung, but some are more common to do so, including: Bladder cancer, Breast cancer, Colorectal cancer, Kidney cancer, Melanoma, Sarcomas, and ______.

<p>Testicular</p> Signup and view all the answers

Mesothelioma in lungs: Treatment is largely ineffective, and prognosis is poor. Few patients survive longer than 18 months after diagnosis. Lung metastases may not cause any symptoms initially. The symptoms will vary depending on the number of tumours and their location in the lungs. Almost any cancer can metastasize to the lung, but some are more common to do so, including: Bladder cancer, Breast cancer, Colorectal cancer, Kidney cancer, Melanoma, Sarcomas, and ______.

<p>Testicular</p> Signup and view all the answers

Intratumor heterogeneity in lung cancers: Treatment is largely ineffective, and prognosis is poor. Few patients survive longer than 18 months after diagnosis. Lung metastases may not cause any symptoms initially. The symptoms will vary depending on the number of tumours and their location in the lungs. Almost any cancer can metastasize to the lung, but some are more common to do so, including: Bladder cancer, Breast cancer, Colorectal cancer, Kidney cancer, Melanoma, Sarcomas, and ______.

<p>Testicular</p> Signup and view all the answers

Lung metastases: The lungs are a common site of metastasis of other cancers via the lymphatic system or the bloodstream. Cancers can spread to any location in the lungs, but most metastatic cancers develop near the edges of the lungs and in the lower lobes. There can be a single metastasis in one lung or many metastases in one or both lungs. Lung metastases may not cause any symptoms initially. The symptoms will vary depending on the number of tumours and their location in the lungs. Almost any cancer can metastasize to the lung, but some are more common to do so, including: Bladder cancer, Breast cancer, Colorectal cancer, Kidney cancer, Melanoma, Sarcomas, and ______.

<p>Testicular</p> Signup and view all the answers

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