Pathophysiology of COVID-19 Severity

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What is the name of the novel beta-coronavirus that causes COVID-19?

SARS-CoV-2

What percentage of confirmed SARS-CoV-2 cases are estimated to be mild according to preliminary reports from the Chinese Center for Disease Control and Prevention?

81%

What percentage of confirmed SARS-CoV-2 cases progress to severe pneumonia according to preliminary reports from the Chinese Center for Disease Control and Prevention?

14%

Which of the following is a potential outcome for SARS-CoV-2 cases progressing to severe pneumonia, according to preliminary reports?

Acute respiratory distress syndrome (ARDS)

What is the reported number of global confirmed cases of COVID-19 as of June 15, 2020?

Over 8 million

What is the term for the branch of study concerning disordered physiological processes that cause, result from, or are associated with a disease or injury?

Pathophysiology

Which discipline describes conditions typically observed during a disease state?

Pathology

What does pathophysiology seek to explain?

The functional changes due to a disease or pathologic state

From which Ancient Greek words does the term 'pathophysiology' come from?

πάθος (pathos) and φυσιολογία (phisiologia)

In which country did Johannes Müller lead the establishment of physiology research autonomous from medical research in the 1830s?

Germany

Explore the mechanisms underlying the severity and progression of COVID-19 in this review. Learn about the wide spectrum of clinical severity and the unclear pathophysiological mechanisms that contribute to disease severity and progression.

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