10 Questions
Which of the following is a learning objective for the series on pathology of the peripheral nervous system?
Identifying the cause and pathogenesis of specific syndromes
Which of the following is a part of the learning objectives for the series?
Differentiating between primary and secondary demyelinating injuries in the PNS
What is the process described in the learning objectives that occurs in the PNS?
Wallerian degeneration
Which type of injury affecting the PNS is mentioned in the learning objectives?
Secondary demyelinating injury
What is a limitation mentioned in the learning objectives regarding peripheral nerve biopsy in a live veterinary patient?
Inability to identify axonal injuries
What is the role of acetylcholine esterase in the neuromuscular junction?
It breaks down acetylcholine in the extracellular space.
What is the main function of the myelin sheath in the peripheral nervous system?
To insulate and increase the speed of impulse conduction along the axon.
What is the role of retrograde transport in neuronal cells?
To transport degradation products from the axon towards the neuronal body.
How are axons outside of the central nervous system myelinated?
By Schwann cells.
What is the function of the nodes of Ranvier in myelinated axons?
To allow for the propagation of action potentials by exposing voltage-gated sodium channels.
Study Notes
Learning Objectives for Pathology of the Peripheral Nervous System
- Identify the learning objectives for the series on pathology of the peripheral nervous system
Processes in the PNS
- The process of retrograde transport occurs in the PNS, where materials are transported from the axon terminal back to the cell body
Injuries Affecting the PNS
- One type of injury affecting the PNS mentioned in the learning objectives is a peripheral nerve injury
Limitations of Peripheral Nerve Biopsy
- A limitation mentioned in the learning objectives is that peripheral nerve biopsy is not feasible in a live veterinary patient due to the potential for causing further nerve damage
Neuromuscular Junction
- Acetylcholine esterase plays a key role in the neuromuscular junction by breaking down acetylcholine, a neurotransmitter, after it has transmitted a signal
Myelination in the PNS
- The main function of the myelin sheath in the peripheral nervous system is to insulate and facilitate the transmission of nerve impulses
- Axons outside of the central nervous system are myelinated by Schwann cells
- The nodes of Ranvier in myelinated axons are the gaps in the myelin sheath where saltatory conduction occurs, allowing for rapid transmission of nerve impulses
Test your knowledge of the pathology of the peripheral nervous system with this quiz by Dr. Duncan Russell. Learn about responses to injury in the PNS and build clinical acumen in recognizing, treating, and prognosticating spontaneous PNS diseases affecting veterinary species.
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