Pathology of the Nervous System: Hydrocephalus and CSF

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What is the main function of cerebrospinal fluid (CSF)?

To protect the brain from injury

What is the name of the structure that produces CSF?

Choroid plexus

What is the term for the abnormal accumulation of CSF in the brain?

Hydrocephalus

Which type of hydrocephalus is caused by obstruction within the ventricular system?

Non-communicating hydrocephalus

What is the name of the congenital malformation that involves the cerebellum and fourth ventricle?

Dandy-Walker syndrome

Which of the following is NOT a cause of hydrocephalus?

Hypertension

What is the gold standard for diagnosing meningitis?

CSF analysis

What is the primary function of myelin in the nervous system?

To protect axons

What is the result of severe damage to axons in Multiple Sclerosis?

Destruction of the nerve/axon itself

Which type of meningitis is characterized by a turbid CSF with a high WBC count and very low glucose levels?

Bacterial meningitis

What is the purpose of reducing ICP in the management of meningitis?

To reduce intracranial pressure

What is the term for the hardening of fibrous tissue due to the destruction of myelin in Multiple Sclerosis?

Sclerosis

What is the complication of micro-aneurysms in blood vessels?

Bleeding

What is the cause of embolic stroke?

Detachment of a thrombus from the site of a plaque or from other sources of embolus

What is the effect of amyloid angiopathy on blood vessels?

Weaken the blood vessel and increase the risk of bleeding

What is the characteristic of fibromuscular dysplasia in an artery wall?

Abnormal growth within the wall of an artery, making it fragile and prone to rupture

What is the primary cause of meningitis?

Encapsulated microorganisms that resist phagocytosis

What is the typical feature of thrombotic strokes compared to embolic strokes?

They are larger in size

What is the risk factor for stroke mentioned in the passage?

All of the above

What is the characteristic of aseptic meningitis?

It is caused by viruses and resolves without specific treatment

What is the result of photophobia in meningitis?

Pain and discomfort due to optic nerve compression

What is the common symptom of meningitis in neonates?

Poor feed

What is the effect of bacterial meningitis on the brain?

It can cause brain damage and death

What is the effect of meningitis on the blood vessels?

Vasodilatation leading to increased blood vessel permeability

What is the role of the receptor expressed by the abnormal clone of T cytotoxic cells in MS?

Allowing the cells to cross the blood-brain barrier

What is the result of the activation of the abnormal clone of T-cells in MS?

Production of cytokines and cellular mediators

What is the role of T-regulator cells in MS?

Suppressing the immune system and improving re-myelination

What is the long-term consequence of the pathogenesis of MS?

Failure of re-myelination and permanent demyelination

What is the effect of the plaques formed in MS on neurotransmission?

Inhibiting neurotransmission

What is the characteristic of the symptoms of MS in terms of the location of the plaques?

The symptoms are dependent on the location of the plaques

Test your knowledge on the pathology of the nervous system, focusing on hydrocephalus and the formation and flow of cerebrospinal fluid (CSF). Learn about the causes and effects of abnormal CSF accumulation and its relation to brain abnormalities and cancer.

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