Pathology of the Gastrointestinal Tract: Stomach Part 2
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Questions and Answers

What is the primary risk factor for peptic ulcer disease in American men?

  • Smoking
  • H.pylori gastritis
  • Lifetime risk of 10% (correct)
  • Chronic NSAID use
  • Which symptom is most commonly associated with peptic ulcer disease?

  • Chest pain
  • Weight gain
  • Epigastric pain (correct)
  • Constant diarrhea
  • In which scenario can acute gastric ulceration occur?

  • As part of a severe stress response (correct)
  • Following regular scheduled meals
  • As a complication of common cold
  • Due to chronic smoking habits
  • What can result in acute gastric ulceration due to extreme hyperacidity?

    <p>Zollinger-Ellison syndrome</p> Signup and view all the answers

    Which of the following is NOT a major aetiological factor for peptic ulcer disease?

    <p>Infection with E.coli</p> Signup and view all the answers

    Study Notes

    Peptic Ulcer Disease

    • Lifetime risk of developing peptic ulcers is 10% for American men and 4% for American women.
    • Most commonly affects middle-aged to older adults.
    • Major aetiological factors include:
      • Hyperacidity
      • H. pylori gastritis
      • Duodenal reflux
      • Use of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)
      • Smoking habits
      • Genetic predisposition

    Clinical Features

    • Characterized by epigastric pain (burning or aching sensation).
    • Pain tends to worsen at night or occurs 1-3 hours post meal.
    • Additional symptoms include nausea, vomiting, belching, and unexplained weight loss.

    Types of Ulcers

    • Ulcers are categorized as either acute or chronic.

    Acute Gastric Ulceration

    • Can arise as part of acute gastritis or due to severe stress conditions.
    • Associated with:
      • Curling ulcers following severe burns
      • Major trauma incidents
      • Cerebrovascular accidents (CVA)
      • Increased intracranial pressure
      • Extreme hyperacidity, such as in Zollinger-Ellison Syndrome, characterized by heightened gastrin secretion.

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    Description

    Explore the intricate details of gastrointestinal pathology in this quiz focusing on the second part of stomach pathology. Topics covered include peptic ulcer disease, various miscellaneous conditions, and gastric neoplasia, both benign and malignant. Test your understanding of these critical aspects of anatomical pathology.

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