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Questions and Answers
What is the primary risk factor for peptic ulcer disease in American men?
What is the primary risk factor for peptic ulcer disease in American men?
- Smoking
- H.pylori gastritis
- Lifetime risk of 10% (correct)
- Chronic NSAID use
Which symptom is most commonly associated with peptic ulcer disease?
Which symptom is most commonly associated with peptic ulcer disease?
- Chest pain
- Weight gain
- Epigastric pain (correct)
- Constant diarrhea
In which scenario can acute gastric ulceration occur?
In which scenario can acute gastric ulceration occur?
- As part of a severe stress response (correct)
- Following regular scheduled meals
- As a complication of common cold
- Due to chronic smoking habits
What can result in acute gastric ulceration due to extreme hyperacidity?
What can result in acute gastric ulceration due to extreme hyperacidity?
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Which of the following is NOT a major aetiological factor for peptic ulcer disease?
Which of the following is NOT a major aetiological factor for peptic ulcer disease?
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Study Notes
Peptic Ulcer Disease
- Lifetime risk of developing peptic ulcers is 10% for American men and 4% for American women.
- Most commonly affects middle-aged to older adults.
- Major aetiological factors include:
- Hyperacidity
- H. pylori gastritis
- Duodenal reflux
- Use of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)
- Smoking habits
- Genetic predisposition
Clinical Features
- Characterized by epigastric pain (burning or aching sensation).
- Pain tends to worsen at night or occurs 1-3 hours post meal.
- Additional symptoms include nausea, vomiting, belching, and unexplained weight loss.
Types of Ulcers
- Ulcers are categorized as either acute or chronic.
Acute Gastric Ulceration
- Can arise as part of acute gastritis or due to severe stress conditions.
- Associated with:
- Curling ulcers following severe burns
- Major trauma incidents
- Cerebrovascular accidents (CVA)
- Increased intracranial pressure
- Extreme hyperacidity, such as in Zollinger-Ellison Syndrome, characterized by heightened gastrin secretion.
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