Peptic Ulcer Disease Flashcards
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Questions and Answers

Which of these statements about gastric ulcers are true? (Select all that apply)

  • Gastric ulcers tend to occur in the lesser curvature/prepyloric area. (correct)
  • Gastric ulcers are more common than duodenal ulcers.
  • Gastric ulcers typically cause weight gain.
  • Gastric ulcers are associated with a risk of malignancy. (correct)
  • Which symptoms are related to the clinical presentation of Peptic Ulcer Disease (PUD)? (Select all that apply)

  • Burning epigastric pain (correct)
  • Weight gain (correct)
  • Board-like rigidity (correct)
  • Haematemesis (correct)
  • What is a common cause of Peptic Ulcer Disease?

    H.pylori infection

    Where are peptic ulcers most commonly located according to the modified Johnson classification?

    <p>Duodenal bulb/gastric antrum and prepyloric area</p> Signup and view all the answers

    How do duodenal ulcers on the posterior wall present?

    <p>e.g. symptoms may vary, but could involve acute abdominal pain.</p> Signup and view all the answers

    Study Notes

    Comparison of Gastric and Duodenal Ulcers

    • Gastric ulcers are less common, typically found in the lesser curvature and prepyloric area of the stomach.
    • Gastric ulcers present with recurrent vomiting, low appetite (LOW), and epigastric tenderness, with a risk of malignancy.
    • Duodenal ulcers are more common, usually located in the first part of the duodenum (D1).
    • Duodenal ulcers do not usually cause vomiting; instead, they may lead to weight gain and right hypochondriac (RHC) tenderness.
    • Unlike gastric ulcers, duodenal ulcers carry no risk of malignancy.

    Clinical Presentation of Peptic Ulcer Disease (PUD)

    • Dyspepsia symptoms include burning and gnawing epigastric pain related to ulcers, along with discomfort, early satiety, bloating, and belching due to dysmotility.
    • Bleeding can present as mild, chronic forms leading to iron deficiency anemia, or severe, acute forms resulting in hematemesis and melena.
    • Perforation results in an acute abdomen characterized by sudden onset abdominal pain and board-like rigidity.

    Aetiology of Peptic Ulcer Disease

    • The primary cause is infection with Helicobacter pylori.
    • Nonsteroidal anti-inflammatory drugs (NSAIDs) contribute to ulcer development in a dose-dependent manner.
    • Other contributing factors include smoking, alcohol consumption, psychological stress, and corticosteroid use.

    Common Locations of Peptic Ulcers

    • Peptic ulcers commonly occur in the duodenal bulb and gastric antrum, particularly in the prepyloric area, classified as Type II and III ulcers.
    • Type II and III ulcers are most associated with acid hypersecretion.

    Presentation of Duodenal Ulcers Based on Location

    • Ulcers located on the posterior wall of the duodenum may present with specific symptoms distinct from those in other locations.

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    Test your knowledge on Peptic Ulcer Disease through these flashcards. Compare gastric and duodenal ulcers and understand their clinical presentations. Perfect for medical students and healthcare professionals!

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