Questions and Answers
Which of these statements about gastric ulcers are true? (Select all that apply)
Which symptoms are related to the clinical presentation of Peptic Ulcer Disease (PUD)? (Select all that apply)
What is a common cause of Peptic Ulcer Disease?
H.pylori infection
Where are peptic ulcers most commonly located according to the modified Johnson classification?
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How do duodenal ulcers on the posterior wall present?
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Study Notes
Comparison of Gastric and Duodenal Ulcers
- Gastric ulcers are less common, typically found in the lesser curvature and prepyloric area of the stomach.
- Gastric ulcers present with recurrent vomiting, low appetite (LOW), and epigastric tenderness, with a risk of malignancy.
- Duodenal ulcers are more common, usually located in the first part of the duodenum (D1).
- Duodenal ulcers do not usually cause vomiting; instead, they may lead to weight gain and right hypochondriac (RHC) tenderness.
- Unlike gastric ulcers, duodenal ulcers carry no risk of malignancy.
Clinical Presentation of Peptic Ulcer Disease (PUD)
- Dyspepsia symptoms include burning and gnawing epigastric pain related to ulcers, along with discomfort, early satiety, bloating, and belching due to dysmotility.
- Bleeding can present as mild, chronic forms leading to iron deficiency anemia, or severe, acute forms resulting in hematemesis and melena.
- Perforation results in an acute abdomen characterized by sudden onset abdominal pain and board-like rigidity.
Aetiology of Peptic Ulcer Disease
- The primary cause is infection with Helicobacter pylori.
- Nonsteroidal anti-inflammatory drugs (NSAIDs) contribute to ulcer development in a dose-dependent manner.
- Other contributing factors include smoking, alcohol consumption, psychological stress, and corticosteroid use.
Common Locations of Peptic Ulcers
- Peptic ulcers commonly occur in the duodenal bulb and gastric antrum, particularly in the prepyloric area, classified as Type II and III ulcers.
- Type II and III ulcers are most associated with acid hypersecretion.
Presentation of Duodenal Ulcers Based on Location
- Ulcers located on the posterior wall of the duodenum may present with specific symptoms distinct from those in other locations.
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Description
Test your knowledge on Peptic Ulcer Disease through these flashcards. Compare gastric and duodenal ulcers and understand their clinical presentations. Perfect for medical students and healthcare professionals!