Pathology of MPGN Type I and Type II
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Questions and Answers

What is a common feature of Minimal Change Nephropathy?

  • Basement membrane thickening
  • Capillary wall necrosis
  • Proliferation of mesangial cells (correct)
  • Crescent formation
  • Which type of Glomerulonephritis is characterized by immune complex deposits and is typically preceded by infection, most commonly streptococcal?

  • Membranoproliferative Glomerulonephritis Type II
  • IgA Mesangial Disease
  • Focal Segmental Proliferative Glomerulonephritis (correct)
  • Membranoproliferative Glomerulonephritis Type I
  • What distinguishes Membranoproliferative Glomerulonephritis Type II from Type I?

  • Mesangial cell proliferation (correct)
  • Basement membrane thickening
  • Capillary wall necrosis
  • Crescent formation
  • Which pattern of glomerular disease may not affect all glomeruli uniformly?

    <p>Segmental</p> Signup and view all the answers

    What is a characteristic histology finding in IgA Mesangial Disease?

    <p>Immune complex deposits (subendothelial)</p> Signup and view all the answers

    What is the most common cause of glomerulonephritis in adults?

    <p>IgA Mesangial Disease</p> Signup and view all the answers

    Which type of glomerulonephritis is characterized by fusion of the foot processes of podocytes?

    <p>Minimal Change Nephropathy</p> Signup and view all the answers

    Which type of glomerulonephritis causes haematuria, nephrotic syndrome, or mixed nephrotic/nephritic presentation?

    <p>Membranoproliferative Glomerulonephritis Type I</p> Signup and view all the answers

    Which glomerular disease presents with dense deposits of complement C3 in the basement membrane?

    <p>Membranoproliferative Glomerulonephritis Type II</p> Signup and view all the answers

    Which glomerular disease is commonly associated with systemic diseases like endocarditis and vasculitis?

    <p>Focal Segmental Proliferative Glomerulonephritis</p> Signup and view all the answers

    Which glomerular disease is the most common cause of nephrotic syndrome in childhood?

    <p>Minimal Change Nephropathy</p> Signup and view all the answers

    Which type of glomerulonephritis is characterized by immune complex deposits in the basement membrane of all segments of all glomeruli, without inflammation or cell proliferation?

    <p>Membranous Nephropathy</p> Signup and view all the answers

    Which stain is used to identify carbohydrates in the basement membrane in Membranous Nephropathy?

    <p>Jones silver stain</p> Signup and view all the answers

    In Membranoproliferative Glomerulonephritis (MPGN), what is the primary cause of basement membrane thickening?

    <p>Mesangial cell proliferation</p> Signup and view all the answers

    What defines Membranoproliferative Glomerulonephritis Type I (MPGN I) among the two types?

    <p>Presence of subendothelial immune complex deposits</p> Signup and view all the answers

    Which condition is associated with deposition of immune complexes on the epithelial side of the basement membrane and subsequent formation of new basement membrane around these deposits?

    <p>Membranous Nephropathy</p> Signup and view all the answers

    What is the approximate outcome for patients affected by Membranous Nephropathy?

    <p>All of the above</p> Signup and view all the answers

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