Pathology of MPGN Type I and Type II

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What is a common feature of Minimal Change Nephropathy?

Proliferation of mesangial cells

Which type of Glomerulonephritis is characterized by immune complex deposits and is typically preceded by infection, most commonly streptococcal?

Focal Segmental Proliferative Glomerulonephritis

What distinguishes Membranoproliferative Glomerulonephritis Type II from Type I?

Mesangial cell proliferation

Which pattern of glomerular disease may not affect all glomeruli uniformly?

Segmental

What is a characteristic histology finding in IgA Mesangial Disease?

Immune complex deposits (subendothelial)

What is the most common cause of glomerulonephritis in adults?

IgA Mesangial Disease

Which type of glomerulonephritis is characterized by fusion of the foot processes of podocytes?

Minimal Change Nephropathy

Which type of glomerulonephritis causes haematuria, nephrotic syndrome, or mixed nephrotic/nephritic presentation?

Membranoproliferative Glomerulonephritis Type I

Which glomerular disease presents with dense deposits of complement C3 in the basement membrane?

Membranoproliferative Glomerulonephritis Type II

Which glomerular disease is commonly associated with systemic diseases like endocarditis and vasculitis?

Focal Segmental Proliferative Glomerulonephritis

Which glomerular disease is the most common cause of nephrotic syndrome in childhood?

Minimal Change Nephropathy

Which type of glomerulonephritis is characterized by immune complex deposits in the basement membrane of all segments of all glomeruli, without inflammation or cell proliferation?

Membranous Nephropathy

Which stain is used to identify carbohydrates in the basement membrane in Membranous Nephropathy?

Jones silver stain

In Membranoproliferative Glomerulonephritis (MPGN), what is the primary cause of basement membrane thickening?

Mesangial cell proliferation

What defines Membranoproliferative Glomerulonephritis Type I (MPGN I) among the two types?

Presence of subendothelial immune complex deposits

Which condition is associated with deposition of immune complexes on the epithelial side of the basement membrane and subsequent formation of new basement membrane around these deposits?

Membranous Nephropathy

What is the approximate outcome for patients affected by Membranous Nephropathy?

All of the above

Learn about the pathology of Membranoproliferative Glomerulonephritis (MPGN) Type I and Type II, including the key differences in cellular proliferation and thickening of capillaries. Understand the clinical manifestations and diagnostic features of MPGN.

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