Pathology of Breast I: Breast Disorders

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Questions and Answers

Which hormone is essential for lactation?

  • Human chorionic gonadotropin (hCG)
  • Progesterone
  • Prolactin (correct)
  • Estrogen

What is the functional unit of the breast where milk is produced?

  • Acini cluster
  • Lobule (correct)
  • Stroma
  • Duct

What is a common complaint related to galactorrhea?

  • Weight gain
  • Nipple discharge (correct)
  • Decreased libido
  • Insomnia

Which condition presents as breast mass with thick, white discharge primarily in older multiparous women?

<p>Mammary duct ectasia (D)</p> Signup and view all the answers

What is the major effect of estrogens on breast tissue during pregnancy?

<p>Increases breast size (A)</p> Signup and view all the answers

Which male endocrine disorder is associated with gynecomastia?

<p>Klinefelter syndrome (B)</p> Signup and view all the answers

What histological feature distinguishes lactational mastitis from breast cancer?

<p>Presence of multinucleated giant cells (A)</p> Signup and view all the answers

What is the hormone that inhibits prolactin and decreases milk production?

<p>Dopamine (B)</p> Signup and view all the answers

What is a characteristic feature of fat necrosis on mammogram?

<p>Microcalcifications (C)</p> Signup and view all the answers

Which hormone has a cyclic effect on breast size during the menstrual cycle?

<p>Estrogen (D)</p> Signup and view all the answers

Which breast disorder is characterized by inflammation that can progress to abscess requiring drainage?

<p>Periductal mastitis (B)</p> Signup and view all the answers

What is the main characteristic of fibrocystic changes in the breast?

<p>Benign nature (A)</p> Signup and view all the answers

Which benign breast tumor is hormone-sensitive and typically shows increased size during pregnancy?

<p>Fibroadenoma (D)</p> Signup and view all the answers

What are the characteristic features of intraductal papillomas in the breast?

<p>Bloody/serous discharge (D)</p> Signup and view all the answers

Which type of fibroadenoma is associated with a high risk of malignancy?

<p>Complex fibroadenoma (A)</p> Signup and view all the answers

Which breast disorder involves squamous metaplasia due to smoking-induced inflammation?

<p>Periductal mastitis (B)</p> Signup and view all the answers

Which stromal tumor of the breast is characterized by epithelial and stromal tissue growth, with variants that can metastasize?

<p>Phyllodes tumor (B)</p> Signup and view all the answers

What distinguishes proliferative breast disorders from fibrocystic changes?

<p>&quot;Proliferation of epithelial cells&quot; (A)</p> Signup and view all the answers

"Apocrine metaplasia" in the breast is also known as what?

<p>&quot;Benign epithelial alteration&quot; (D)</p> Signup and view all the answers

Which of the following microscopic findings characterizes mammary duct ectasia?

<p>Periductal inflammation and dilation of ducts, with foamy histiocytes within the luminal secretions and infiltrating the wall of ducts (A)</p> Signup and view all the answers

Where does the lactiferous sinus begin?

<p>TDLU (terminal duct lobular unit) (A)</p> Signup and view all the answers

How many duct openings are found on the surface of the nipple?

<p>15 to 20 (C)</p> Signup and view all the answers

Which hormone is essential for lactation when other essential hormones are present?

<p>Prolactin (C)</p> Signup and view all the answers

What is the most common type of bladder cancer?

<p>Urothelial cancers (D)</p> Signup and view all the answers

What is the biggest risk factor for bladder cancer?

<p>Smoking (C)</p> Signup and view all the answers

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