Breast Pathology: Inflammatory Disorders Quiz

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38 Questions

Which bacterial species commonly invades breast tissue in cases of acute mastitis?

Streptococcus aureus

What is the typical presentation of periductal mastitis in affected individuals?

Painful erythematous subareolar mass

What characterizes the pathology of acute mastitis?

Localized area of acute inflammation progressing to abscess formation

What is a common symptom associated with acute mastitis?

Febrile illness with painful, erythematous breast

What is the most common timing for the occurrence of acute mastitis?

During lactation

What is the primary risk factor associated with periductal mastitis?

Cessation of cigarette smoking

What is the most common malignancy in women according to the text?

Carcinoma of the breast

Which histologic feature is the key characteristic of mammary duct ectasia?

Dilation of ducts and inspissation of breast secretions

What is the key histologic feature of breast fibrosis?

Rupture of cysts leading to chronic inflammation and fibrosis

What is defined by the presence of more than two cell layers according to the text?

Epithelial hyperplasia

What tends to occur in the fifth or sixth decade of life, usually in multiparous women?

Mammary duct ectasia

What do small cysts form by, according to the text?

Dilation of lobules

"Cysts are lined either by a flattened atrophic epithelium or by metaplastic apocrine cells." - According to the text, which condition does this statement refer to?

"Breast cysts"

What is characterized chiefly by dilation of ducts, inspissation of breast secretions, and a marked periductal and interstitial chronic granulomatous inflammatory reaction?

"Mammary duct ectasia"

What tends to peak at the age of 75–80 years and then decline slightly thereafter?

Incidence of carcinoma of the breast

What is the most common age range for the occurrence of mammary duct ectasia?

Fifth or sixth decade of life

What characterizes osteoblastoma when it involves the spine?

It is larger than 2 cm and causes dull, achy pain

Which condition is a well-circumscribed mass of hemorrhagic gritty tan tissue composed of randomly interconnecting trabeculae of woven bone rimmed by osteoblasts?

Osteoid osteoma

In which age group does osteosarcoma predominantly occur?

Teenagers between 15 and 18 years old

What is the most common benign bone tumor?

Osteochondroma

Which tumor is composed of malignant hyaline and myxoid cartilage?

Chondrosarcoma

What characterizes the gross morphology of chondromas?

They are small, gray-blue translucent nodules of cytologically benign hyaline cartilage

When does chondrosarcoma typically affect individuals?

Individuals in their 40s or older

What is the favored site for the occurrence of osteosarcomas?

The long bones of the extremities

What is the key histologic feature of osteochondromas?

They are benign cartilage-capped tumors attached to the skeleton by a bony stalk

What characterizes the stroma surrounding neoplastic bone in osteoblastoma and osteoid osteoma?

It contains many dilated and congested capillaries

What is the term used to describe benign bone tumors that have identical histologic features but differ in size, sites of origin, and symptoms?

Osteoid osteoma and osteoblastoma

What is the characteristic symptom associated with osteoid osteomas?

Severe nocturnal pain relieved by aspirin

Which of the following is NOT a predisposing factor associated with bone neoplasia?

Osteochondromas

Which genetic alterations play a role in the development of most bone tumors?

Somatic mutations

What age group usually experiences the occurrence of osteoid osteomas?

Teens and 20s

Which factor is associated with bone neoplasia according to the text?

Paget disease

Which genetic alterations are known to play a role in the development of most bone tumors?

Chromosomal abnormalities

What are the predisposing factors associated with bone neoplasia according to the text?

Metal prostheses

How do osteoid osteomas and osteoblastomas differ?

Size and symptoms

What is the characteristic presentation of osteoid osteoma according to the text?

Severe nocturnal pain

Which condition is defined by dilation of ducts, inspissation of breast secretions, and a marked periductal inflammatory reaction?

Mammary duct ectasia

What characterizes the pathology of acute mastitis?

Periductal and interstitial chronic granulomatous inflammatory reaction

Test your knowledge of inflammatory disorders, benign epithelial lesions, and tumors related to the breast in the context of pathology. This quiz covers topics such as acute mastitis, making it relevant for students studying the musculoskeletal system and pathology of the breast.

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