Pathology of Bone Neoplastic Disorders Quiz
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Questions and Answers

Which aspect of a bone lesion is crucial for determining whether the lesion is benign or malignant?

  • The pattern of growth (correct)
  • The anatomical diagnosis
  • The location within the bone
  • The size of the lesion
  • What is a characteristic feature of osteoma, a rare benign bone tumor?

  • High metastatic potential
  • Usually asymptomatic (correct)
  • Presence of cartilage in the lesion
  • Frequent association with hyperparathyroidism
  • In the context of bone tumors, what does the common phrase 'Location! Location! Location!' refer to?

  • The anatomical diagnosis
  • The location within the bone (correct)
  • The presence of metastases
  • The size of the tumor
  • What is the abbreviation for a bone tumor that affects the physis or growth plate?

    <p>CMF</p> Signup and view all the answers

    Which type of bone tumor is more likely to cause local and mechanical problems?

    <p>Osteoma</p> Signup and view all the answers

    What aspect of a bone lesion does NOT usually correlate with the clinical picture and radiographic appearance?

    <p>Size of the lesion</p> Signup and view all the answers

    Which bone tumor is characterized by a well-delimited nodule on X-ray, slow-growing, and has a good prognosis with simple excision?

    <p>Osteoblastoma</p> Signup and view all the answers

    What is a distinguishing feature between osteoblastoma and osteoid osteoma in terms of pain relief?

    <p>Pain relieved by aspirin in osteoid osteoma, but not in osteoblastoma</p> Signup and view all the answers

    Which bone tumor is more common in the teens to twenties age group, located in the vertebral column, and has a radiolucent nidus with less or no sclerotic rim on X-ray?

    <p>Osteoid osteoma</p> Signup and view all the answers

    What is the histologic appearance of both osteoid osteoma and osteoblastoma?

    <p>Interlacing trabeculae of woven bone surrounded by osteoblasts; loose connective tissue stroma</p> Signup and view all the answers

    Which bone tumor is a malignant mesenchymal tumor characterized by neoplastic cells producing osteoid and sometimes cartilage, most commonly affecting patients in a bimodal age distribution?

    <p>Osteosarcoma</p> Signup and view all the answers

    Which bone tumor is referred to as the 'giant osteoid osteoma' and presents on X-ray with a central radiolucent nidus surrounded by a rim of sclerotic bone?

    <p>Osteoblastoma</p> Signup and view all the answers

    What characteristic differentiates osteoid osteoma from osteoblastoma in terms of pain relief?

    <p>Pain in osteoid osteoma is relieved by aspirin, while pain in osteoblastoma is not.</p> Signup and view all the answers

    Which bone tumor is characterized by having a radiolucent nidus on X-ray with less or no sclerotic rim?

    <p>Osteoblastoma</p> Signup and view all the answers

    In terms of size, which bone tumor is generally larger between osteoid osteoma and osteoblastoma?

    <p>Osteoblastoma</p> Signup and view all the answers

    Which bone tumor presents a central radiolucent nidus surrounded by a rim of sclerotic bone on X-ray?

    <p>Osteoblastoma</p> Signup and view all the answers

    What feature differentiates the histologic appearance of osteosarcoma from that of osteoblastoma and osteoid osteoma?

    <p>Presence of neoplastic cells producing unmineralized bone matrix</p> Signup and view all the answers

    Which bone tumor is the most common primary malignant tumor of bone?

    <p>Osteosarcoma</p> Signup and view all the answers

    Which age group is more likely to be affected by osteosarcoma?

    <p>Teens-twenties</p> Signup and view all the answers

    What is the significance of the phrase 'Location! Location! Location!' in the context of bone tumors?

    <p>Emphasizes the importance of anatomical location in diagnosing bone tumors</p> Signup and view all the answers

    What is the typical growth pattern of osteoma, a rare benign bone tumor?

    <p>Asymptomatic growth with local and mechanical problems</p> Signup and view all the answers

    What is a distinguishing feature between chondrosarcoma and osteosarcoma based on cellular characteristics and imaging studies?

    <p>Chondrosarcoma produces osteoid matrix, while osteosarcoma produces cartilaginous matrix</p> Signup and view all the answers

    How does fibrous dysplasia differ from giant cell tumor regarding their anatomical locations?

    <p>Fibrous dysplasia commonly involves the skull, while giant cell tumor affects long bones</p> Signup and view all the answers

    What is a common misconception regarding osteoid osteoma and its presentation?

    <p>It usually requires complex surgical excision for complete removal</p> Signup and view all the answers

    Which factor plays a critical role in determining whether a bone lesion is benign or malignant?

    <p>Histological appearance of the lesion cells</p> Signup and view all the answers

    How do non-ossifying fibroma (NOF) and simple bone cyst (SBC) differ based on their radiographic appearance?

    <p>NOF presents as a well-defined nodule, while SBC shows a cystic lesion with fluid-fluid levels</p> Signup and view all the answers

    'Hyperparathyroidism with Brown tumor' refers to a bone tumor that is associated with which underlying condition?

    <p><em>Osteomalacia</em></p> Signup and view all the answers

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