COPY: Pathology of Amyloidosis and Tissue Deposits

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is amyloidosis?

The extracellular deposition of abnormal protein

Which of the following are types of amyloid material?

Amyloid light (AL) (correct)
Amyloid associated protein (AA) (correct)
Fibril protein (correct)
P component (correct)

What are the two main categories of amyloidosis?

Primary
Systemic (correct)
Localized (correct)
Tertiary
Secondary

What is a common cause of secondary amyloidosis?

Chronic inflammation (A) Signup and view all the answers

Amyloidosis is a common condition that affects most people.

False (B) Signup and view all the answers

What are the gross characteristics of an organ affected by amyloidosis?

All of the above (D) Signup and view all the answers

What are the two main types of microscopic stains used to identify amyloid deposits?

Haematoxylin and eosin stain and Congo red stain Signup and view all the answers

What is the primary complication of renal amyloidosis?

Kidney failure (D) Signup and view all the answers

Which of the following conditions can be caused by amyloidosis in the heart?

All of the above (D) Signup and view all the answers

What is the primary diagnostic tool for amyloidosis?

Biopsy Signup and view all the answers

Which of the following is a common type of connective tissue hyalinosis?

Arterial hyalinization (B) Signup and view all the answers

What is the hallmark of cellular hyalinosis?

The presence of Mallory bodies Signup and view all the answers

Where are Russel bodies typically observed?

Inflammation rich in plasma cells Signup and view all the answers

What is the difference between mucoid and myxomatous change?

Mucoid change occurs when mucin is deposited inside cells, while myxomatous change occurs when mucin is deposited outside cells. Signup and view all the answers

Which of the following conditions is associated with melanin deficiency?

All of the above (D) Signup and view all the answers

What is the main pigment found in hemosiderosis?

Hemosiderin (B) Signup and view all the answers

What is the major difference between hemosiderosis and hemochromatosis?

Hemosiderosis is localized, while hemochromatosis is generalized. (B) Signup and view all the answers

Which of the following can cause anthracosis?

All of the above (D) Signup and view all the answers

What is the cause of gout?

Disturbance in purine metabolism leading to the deposition of sodium urate crystals in tissues. Signup and view all the answers

Where are urate crystals most commonly deposited in gout?

The joints (C) Signup and view all the answers

Which of the following conditions is often associated with secondary gout?

Leukemia (B) Signup and view all the answers

What is another name for metastatic calcification?

Calcinosis Signup and view all the answers

Calcification only occurs in dead tissue.

False (B) Signup and view all the answers

Flashcards

Amyloidosis definition

Abnormal protein deposits in tissues and organs

Amyloid types

Amyloid light chain (AL) is one type.