28 Questions
What is the abnormal accumulation of triglycerides within the cytoplasm of cells known as?
Steatosis
Which of the following is NOT a cause of fatty change?
Regular exercise
What is the term for the buildup of cholesterol within cells?
Cholesterol accumulation
What is a genetic disorder that can contribute to high cholesterol levels?
Familial hypercholesterolemia
High intake of which type of fats can contribute to cholesterol deposition in tissues?
Saturated fats
What is the primary source of exogenous pigments in the body?
Introduced from outside the body
What is the cause of jaundice mentioned in the text?
Hemolytic anemia, biliary obstruction, and hepatocellular disease
What is the term for the disease involving accumulation of excess hemosiderin?
Hemosiderosis
What is the term for the 'wear and tear' pigment that accumulates in cells during aging?
Lipofuscin
What is the primary function of melanin in the body?
Skin pigmentation
What is the cause of hemochromatosis mentioned in the text?
Genetic disorder of iron absorption
What is indicated by the accumulation of a brown pigment in cardiac muscle cells?
Oxidative stress and cellular senescence
What is the cause of black pigmentation of the gums?
Ingestion of contaminated water
What is the result of the deposition of black carbon particles in macrophages?
Anthracosis
What is the condition characterized by the crystallization of uric acid in joints and tissues?
Gout
What is the cause of oxidative stress and cellular senescence in long-lived cells?
Peroxidation of lipid due to free radicals
What is the result of the body producing too much uric acid or excreting too little?
Uric acid accumulation
What is the term for the deposition of a homogenous, glassy, pink material within cells or in the extracellular space?
Hyaline accumulation
What is the characteristic of amyloid accumulation under polarized light?
Shows an apple-green birefringence
What is the term for the accumulation of mucin in the dermis?
Mucinosis
What is the typical cause of Myxomatous Degeneration?
Age-related changes in connective tissue
What is the term for the extracellular deposition of insoluble fibrillar proteins?
Amyloid protein accumulation
What is a common cause of Amyloidosis?
Chronic inflammatory diseases
What is the characteristic of MSU crystals?
Needle-shaped and birefringent
What is a dietary factor that contributes to the accumulation of MSU crystals?
Consumption of foods high in purines
What can impair the elimination of uric acid from the body?
Reduced kidney function
What is the characteristic of calcium deposition in tissues?
Appear as pale, whitish areas in the tissue section
What can cause dystrophic calcification?
Necrosis of tissues
Test your knowledge on intracellular accumulation and extracellular deposition, including fatty change, steatosis, and cholesterol accumulation. Learn about the causes and effects of these cellular changes, often seen in conditions like atherosclerosis and diabetes.
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