Podcast
Questions and Answers
What is a common cause of reversible cell injury?
What is a common cause of reversible cell injury?
- Hypoxia due to oxygen deprivation
- Oxidative stress from free radicals (correct)
- Prolonged exposure to high temperature
- Genetic mutations in cellular DNA
Which of the following best describes irreversible cell injury?
Which of the following best describes irreversible cell injury?
- It only occurs in response to infectious agents.
- It is always temporary.
- It leads to inflammation and repair.
- It results in necrosis or apoptosis. (correct)
Which process is typically associated with cellular necrosis?
Which process is typically associated with cellular necrosis?
- Energy production remains unaffected.
- Cellular swelling and organelle breakdown occur. (correct)
- It results in programmed cell death.
- Cell membrane integrity is preserved.
What role does apoptosis play in cellular health?
What role does apoptosis play in cellular health?
Which statement about cell injury is false?
Which statement about cell injury is false?
Flashcards
Cause of Reversible Cell Injury?
Cause of Reversible Cell Injury?
Free radicals causing damage beyond repair.
Irreversible Cell Injury
Irreversible Cell Injury
Cell death due to damage or a controlled process of self-destruction.
Cellular Necrosis
Cellular Necrosis
Cellular swelling and breakdown of organelles.
Role of Apoptosis
Role of Apoptosis
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False Statement About Cell Injury
False Statement About Cell Injury
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Study Notes
Cell Injury and Reversibility
- Common causes of reversible cell injury include hypoxia, chemical exposure, and infectious agents that temporarily impair cellular function without causing structural damage.
- Reversible cell injury can lead to cellular repair or adaptation if the stressor is removed in time.
Irreversible Cell Injury
- Irreversible cell injury refers to permanent damage to cells resulting in cell death, typically characterized by significant structural changes such as karyolysis, pyknosis, and necrosis.
- Irreversible injury often occurs after prolonged hypoxia or severe toxin exposure that overwhelms cellular repair mechanisms.
Necrosis
- Necrosis is generally associated with processes such as loss of ATP, cell swelling, and inflammation; it results from acute injury leading to cellular breakdown and inflammatory response.
- Necrotic cells often release contents into the extracellular space, triggering an immune response.
Apoptosis and Cellular Health
- Apoptosis, or programmed cell death, is a vital process for maintaining cellular health by eliminating damaged or unnecessary cells without provoking inflammation.
- This controlled process allows for cellular turnover and tissue homeostasis, crucial for development and response to cellular stress.
Cell Injury Myths
- A false statement regarding cell injury might suggest that all cell injuries are irreversible or that all forms of cell death are due to necrosis, overlooking the role of apoptosis and potential recovery from reversible injury.
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