Pathology and Malignancy Overview

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Questions and Answers

The Virchow's Triad describes the development of what?

  • Inflammation
  • Thrombosis (correct)
  • Hyaline Dystrophy
  • Neoplasia

Which cells belong to the macrophage-monocyte system?

  • Basophilic Granulocytes (correct)
  • Kupffer cells (correct)
  • NK-cells (correct)
  • Thrombocytes

What is an anaphylaxis characterized by?

  • Mast-cell degranulation
  • Histamine secretion
  • IgE Production
  • All of the above (correct)

Where does pulmonary oedema occur?

<p>Left-sided heart failure (B)</p> Signup and view all the answers

What is metaplasia?

<p>Replacement of a tissue with another, different tissue type (A)</p> Signup and view all the answers

What is an adenocarcinoma?

<p>A malignant tumor originating from glandular tissue (A)</p> Signup and view all the answers

Adenosarcoma is a recognized type of cancer.

<p>False (B)</p> Signup and view all the answers

What is "grading" in cancer?

<p>Evaluating the tumor's malignancy based on its microscopic features (B)</p> Signup and view all the answers

Which is NOT a cause of fatty liver?

<p>Shock (D)</p> Signup and view all the answers

Proliferative inflammation is characterized by what?

<p>Tuberculosis (B), Sarcoidosis (C)</p> Signup and view all the answers

What type of inflammation does NOT belong to the proliferative category?

<p>Granulomatous net-like inflammation (A), Diphtheria (B), Osteoporosis (D)</p> Signup and view all the answers

What is an atheroma?

<p>A fatty plaque, non-neoplasitic (B)</p> Signup and view all the answers

What is the Nustensche rule?

<p>Rigor mortis spreads from head to foot (B)</p> Signup and view all the answers

Flashcards

Hydrothorax

A condition characterized by fluid build-up in the chest cavity, often due to heart failure or other medical conditions.

Caseous Necrosis

A type of necrosis (cell death) characterized by the formation of a cheesy, white substance, often associated with tuberculosis (TB).

Hypoxic Cell Death

A type of cell death that occurs when a cell is deprived of oxygen, leading to damage and eventual death.

Granulomatous Inflammation

A type of inflammation characterized by the formation of granulomas, which are small clusters of immune cells that wall off the infection.

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Purulent Inflammation

A type of inflammation characterized by the presence of pus, a thick, yellowish fluid containing dead white blood cells.

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Precancerous Condition

A precursor to cancer, often characterized by abnormal cell growth and proliferation.

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Secondary (Renal) Hypertension

Secondary hypertension is caused by conditions that affect the kidneys, leading to high blood pressure.

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Primary Hypertension

Primary hypertension is high blood pressure that has no identifiable cause.

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Spermatogenesis

The process of cell division and differentiation that occurs in the testes to produce sperm cells.

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Oogenesis

The process of cell division and differentiation that occurs in the ovaries to produce egg cells.

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Benign Prostatic Hyperplasia (BPH)

A benign tumor that develops in the prostate gland, often causing urinary problems.

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Prostate Cancer

Cancer of the prostate gland.

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Thermoregulation

A complex process that involves regulating the body's temperature, often through sweating and shivering.

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Water Balance

The process of maintaining the body's water balance, involving the intake, retention, and excretion of water.

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Epidermis

The outer layer of skin, composed of several layers of epithelial cells.

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Melanocyte

A type of cell found in the epidermis that produces melanin, the pigment responsible for skin color.

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Merkel Cell

A type of cell found in the epidermis that acts as a touch receptor, helping us sense touch.

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Wound Regeneration

The process of healing and repair after an injury or wound.

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Cell Differentiation

A process of cell differentiation and maturation, leading to the formation of a specialized cell type.

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Necrosis

A type of cell death that is characterized by the swelling and bursting of the cell, often caused by injury or toxins.

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Carcinoma in Situ (CIS)

A stage in the development of cancer where the tumor is still confined to the original location and has not spread to other tissues.

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Epithelial Carcinoma

A type of cancerous tumor that originates in epithelial tissues, the cells that line the surfaces of organs and cavities.

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Grading

The process of determining the degree of malignancy of a tumor based on microscopic features.

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Staging

The process of classifying a tumor based on its size, location, and spread to nearby tissues or organs.

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Benign Tumor

A type of tumor that is not cancerous and does not spread to other tissues.

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Malignant Tumor

A type of tumor that is cancerous and can spread to other tissues.

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Natural Killer (NK) Cell

A specialized type of immune cell that recognizes and destroys infected or cancerous cells.

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Macrophage

A type of white blood cell that plays a role in the immune response by engulfing and destroying foreign invaders.

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Monocyte

A type of white blood cell that matures into a macrophage.

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Kupffer Cell

A type of cell found in the liver that is responsible for filtering blood and removing harmful substances.

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Langerhans Cell

A type of cell found in the skin that is responsible for presenting antigens to the immune system.

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Study Notes

Active Carcinogens

  • Ionizing radiation such as X-rays, UV light, and radioactive substances (excluding asbestos)

Malignant Tumor Outcomes

  • Usually no dental problems, but can lead to blood clots, fatigue, and illness

Thrombosis and Syndromes

  • Often lead to fatigue, illness, and blood clots

Diseases of the Abdominal Cavity

  • Symptoms include inflammation of the peritoneum, pleura, and other body parts; accompanied by excess fluid in various body cavities

Pathological Conditions

  • Describes the etiology of various diseases, including heart, lung, and liver conditions; also mentions cephalomalacia and other potential complications

Types of Necrosis

  • Cases of necrosis, including tissue death and lack of blood flow

Tumor Grading and Malignancy

  • Grading is an assessment of malignancy; not related to stages. Fatty liver is not linked to alcohol, nicotine, shock, or overeating

Proliferative Inflammation

  • Tuberculosis (TB) and sarcoidosis are examples, but other conditions are omitted.

Exudative Inflammation

  • Diphtheria

Non-Neoplastic and Non-Tumor Conditions

  • Atherosclerosis plaque is not classified as a tumor or neoplasm.

Body Regions

  • A rash or condition affecting the entire body.

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