29 Questions
Which of the following paraneoplastic syndromes is associated with renal adenocarcinoma?
Nodular dermatofibrosis
Which tumor is associated with alopecia and follicular atrophy in the skin?
Pancreatic carcinoma
Which paraneoplastic syndrome is associated with exfoliative dermatitis?
Thymoma
Which tumor is associated with epidermal necrosis?
Pancreatic and Hepatic Tumours
Which paraneoplastic syndrome is associated with nodular dermatofibrosis?
Alopecia
Which of the following is a major cause of cancer-related morbidity and mortality?
Metastasis
What is the process called when cancer cells leave the primary tumour and travel through blood and lymphatic vessels?
Metastasis
What is the primary cause of death in cancer?
Metastasis
Which of the following is involved in the transport of tumour cells in circulation?
All of the above
What is the term for the exit of tumour cells from the blood vessels?
Extravasation
Which step in the metastatic cascade involves tumour cells interacting with platelets, lymphocytes, and other blood components?
Intravasation
Which pathway do ovarian/pancreatic adenocarcinomas prefer to spread through?
Transcoelomic pathway
Which pathway do sarcomas tend to use more frequently than carcinomas?
Haematogenous pathway
Which organ is most commonly affected by metastasis of osteosarcoma?
Lung
Which syndrome is characterized by rapid periosteal new bone growth affecting distal limbs?
Hypertrophic pulmonary osteopathy
Which syndrome is associated with extreme periosteal bone growth on the extremities of the bone?
Hypertrophic pulmonary osteopathy
Which condition is associated with overgrowth of nonneoplastic fibroblasts in the bone marrow?
Myelofibrosis
Which syndrome is characterized by altered carbohydrate, protein, and lipid metabolism resulting in notable weight loss and drop in productivity?
Cancer cachexia
Which neoplasm can cause hypercalcaemia by producing PTH-related protein that binds to PTH receptors in the bones and kidneys?
All of the above
Which neoplasm can cause hypoglycaemia as the most common endocrine complication?
Insulinoma
Which neoplasm produces a normal product of the tissue of origin in functioning endocrine tumors?
Insulinoma
The paraneoplastic syndrome of ________ is associated with thymoma.
Myasthenia gravis
Exfoliative dermatitis is associated with ________.
thymoma
Pancreatic carcinoma is associated with ________ and follicular atrophy in the skin.
alopecia
Renal adenocarcinoma is associated with ________.
nodular dermatofibrosis
Hepatic carcinoma and osteogenic sarcoma are associated with ________.
Myasthenia gravis
Which of the following is the most common cause of hypoglycaemia in cancer?
Insulinoma
Which of the following neoplasms is associated with hypertrophic pulmonary osteopathy?
Lung tumor
Which of the following is a consequence of neoplasia that results in tissue pressure necrosis/atrophy?
Space-occupying lesion
Test your knowledge on the pathological changes associated with benign and metastatic neoplastic disease. Learn about the spread of tumors and the formation of metastases through blood and lymphatic vessels. Understand how invasion and metastasis contribute to cancer-related morbidity.
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