Pathological Changes and Metastatic Neoplastic Disease Quiz
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Questions and Answers

Which of the following paraneoplastic syndromes is associated with renal adenocarcinoma?

  • Exfoliative dermatitis
  • Nodular dermatofibrosis (correct)
  • Epidermal necrosis
  • Alopecia

Which tumor is associated with alopecia and follicular atrophy in the skin?

  • Thymoma
  • Pancreatic carcinoma (correct)
  • Renal adenocarcinoma
  • Hepatic carcinoma

Which paraneoplastic syndrome is associated with exfoliative dermatitis?

  • Nodular dermatofibrosis
  • Epidermal necrosis
  • Thymoma (correct)
  • Alopecia

Which tumor is associated with epidermal necrosis?

<p>Pancreatic and Hepatic Tumours (B)</p> Signup and view all the answers

Which paraneoplastic syndrome is associated with nodular dermatofibrosis?

<p>Alopecia (B)</p> Signup and view all the answers

Which of the following is a major cause of cancer-related morbidity and mortality?

<p>Metastasis (D)</p> Signup and view all the answers

What is the process called when cancer cells leave the primary tumour and travel through blood and lymphatic vessels?

<p>Metastasis (A)</p> Signup and view all the answers

What is the primary cause of death in cancer?

<p>Metastasis (A)</p> Signup and view all the answers

Which of the following is involved in the transport of tumour cells in circulation?

<p>All of the above (D)</p> Signup and view all the answers

What is the term for the exit of tumour cells from the blood vessels?

<p>Extravasation (B)</p> Signup and view all the answers

Which step in the metastatic cascade involves tumour cells interacting with platelets, lymphocytes, and other blood components?

<p>Intravasation (D)</p> Signup and view all the answers

Which pathway do ovarian/pancreatic adenocarcinomas prefer to spread through?

<p>Transcoelomic pathway (A)</p> Signup and view all the answers

Which pathway do sarcomas tend to use more frequently than carcinomas?

<p>Haematogenous pathway (C)</p> Signup and view all the answers

Which organ is most commonly affected by metastasis of osteosarcoma?

<p>Lung (C)</p> Signup and view all the answers

Which syndrome is characterized by rapid periosteal new bone growth affecting distal limbs?

<p>Hypertrophic pulmonary osteopathy (A)</p> Signup and view all the answers

Which syndrome is associated with extreme periosteal bone growth on the extremities of the bone?

<p>Hypertrophic pulmonary osteopathy (D)</p> Signup and view all the answers

Which condition is associated with overgrowth of nonneoplastic fibroblasts in the bone marrow?

<p>Myelofibrosis (B)</p> Signup and view all the answers

Which syndrome is characterized by altered carbohydrate, protein, and lipid metabolism resulting in notable weight loss and drop in productivity?

<p>Cancer cachexia (B)</p> Signup and view all the answers

Which neoplasm can cause hypercalcaemia by producing PTH-related protein that binds to PTH receptors in the bones and kidneys?

<p>All of the above (D)</p> Signup and view all the answers

Which neoplasm can cause hypoglycaemia as the most common endocrine complication?

<p>Insulinoma (C)</p> Signup and view all the answers

Which neoplasm produces a normal product of the tissue of origin in functioning endocrine tumors?

<p>Insulinoma (B)</p> Signup and view all the answers

The paraneoplastic syndrome of ________ is associated with thymoma.

<p>Myasthenia gravis</p> Signup and view all the answers

Exfoliative dermatitis is associated with ________.

<p>thymoma</p> Signup and view all the answers

Pancreatic carcinoma is associated with ________ and follicular atrophy in the skin.

<p>alopecia</p> Signup and view all the answers

Renal adenocarcinoma is associated with ________.

<p>nodular dermatofibrosis</p> Signup and view all the answers

Hepatic carcinoma and osteogenic sarcoma are associated with ________.

<p>Myasthenia gravis</p> Signup and view all the answers

Which of the following is the most common cause of hypoglycaemia in cancer?

<p>Insulinoma (D)</p> Signup and view all the answers

Which of the following neoplasms is associated with hypertrophic pulmonary osteopathy?

<p>Lung tumor (D)</p> Signup and view all the answers

Which of the following is a consequence of neoplasia that results in tissue pressure necrosis/atrophy?

<p>Space-occupying lesion (D)</p> Signup and view all the answers

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