Immune evasion
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Questions and Answers

Which term refers to the accumulation of multiple RNA changes in surface proteins of a virus?

  • Adaptive advantage
  • Antigenic drift (correct)
  • Reassortment
  • Antigenic shunt
  • What happens when two different and distinct viruses infect the same cell at the same time?

  • They trigger an immune response
  • They combine to form a new virus (correct)
  • They cancel each other out
  • They mutate into a more aggressive virus
  • What is the term used to describe a virus that is a combination of two different viruses?

  • Antigenic drift
  • Adaptive advantage
  • Antigenic shift (correct)
  • Recombinant Reassortment
  • How do infectious pathogens prevent apoptosis?

    <p>By inhibiting cell signalling pathways</p> Signup and view all the answers

    What is the main goal of infectious pathogens when infecting immune cells?

    <p>All of the above</p> Signup and view all the answers

    What is the term used to describe when viruses or parasites change the behavior of the host to increase transmission?

    <p>Behaviour changing for transmission</p> Signup and view all the answers

    Why is it important to understand how different pathogens cause disease according to their effect on proinflammatory cytokine response?

    <p>To study immune system evasion mechanisms</p> Signup and view all the answers

    What is the term used to describe the large antigenicity changes in influenza viruses?

    <p>Antigenic shunt</p> Signup and view all the answers

    How do some viruses stimulate cytokine production to further spread the virus?

    <p>By upregulating cell signalling pathways</p> Signup and view all the answers

    Which mechanism is not used by bacteria use to evade the immune system?

    <p>Hijack the cell and reproduce within the cell</p> Signup and view all the answers

    What is the function of virokines/viroceptors?

    <p>To mimic cytokines or cell receptors</p> Signup and view all the answers

    Which type of pathogens can hide in immuno privileged tissues?

    <p>Viruses</p> Signup and view all the answers

    How do herpesviruses evade the immune system?

    <p>By shutting off replication and lying low in tissues</p> Signup and view all the answers

    What is the term used for the antigenic variation in influenza viruses?

    <p>Antigenic drift</p> Signup and view all the answers

    Which of the following is NOT a mechanism used by pathogens to evade the immune system?

    <p>Stimulating immune cells</p> Signup and view all the answers

    What is the function of bacterial capsules in immune evasion?

    <p>To cloak the bacteria and prevent phagocytosis</p> Signup and view all the answers

    Which of the following is an example of a pathogen that can hide in immuno privileged tissues?

    <p>Equine viral arteritis</p> Signup and view all the answers

    What is the term used for the accumulation of mistakes in the RNA genome of viruses?

    <p>Antigenic drift</p> Signup and view all the answers

    What are virokines/viroceptors and how do they help pathogens evade the immune system?

    <p>Virokines/viroceptors are proteins produced by viruses that mimic cytokines or cell receptors. They act as decoys to divert the immune response and prevent detection of the virus.</p> Signup and view all the answers

    How do bacterial capsules contribute to immune evasion?

    <p>Bacterial capsules cloak the surface of bacteria, preventing the immune response from recognizing and phagocytosing the bacteria.</p> Signup and view all the answers

    What is viral latency and how does it allow pathogens to evade the immune system?

    <p>Viral latency is when viruses shut off replication and remain dormant in tissues. By not producing many proteins that are recognized by the immune response, they can evade detection. They reactivate and continue replication during times of stress.</p> Signup and view all the answers

    Give an example of a pathogen that can hide in immuno privileged tissues.

    <p>An example of a pathogen that can hide in immuno privileged tissues is Equine viral arteritis.</p> Signup and view all the answers

    What is antigenic drift and how does it relate to influenza viruses?

    <p>Antigenic drift is the gradual accumulation of genetic mutations in the RNA genome of influenza viruses. This leads to changes in the antigenicity of the virus, allowing it to evade the immune response.</p> Signup and view all the answers

    How do pathogens with an RNA genome accumulate mistakes?

    <p>Pathogens with an RNA genome accumulate mistakes during replication cycles due to the lack of correction mechanisms for RNA. These mistakes can lead to antigenic variation and immune evasion.</p> Signup and view all the answers

    What is antigenic drift and how does it contribute to the variance of influenza viruses?

    <p>Antigenic drift is the accumulation of multiple RNA changes in surface proteins of influenza viruses. It leads to the viruses looking very different, which contributes to their variance.</p> Signup and view all the answers

    What is antigenic shift and how does it occur in influenza viruses?

    <p>Antigenic shunt refers to the mixing and reassortment of two different and distinct viruses that infect the same cell at the same time. This can result in a virus that is a combination of both viruses.</p> Signup and view all the answers

    How do infectious pathogens prevent apoptosis and promote their own survival?

    <p>Some infectious pathogens prevent apoptosis, which is a programmed cell death, by inhibiting or upregulating cell signaling pathways. This helps the pathogens survive and spread.</p> Signup and view all the answers

    What is antigenic variation and why is it important for vaccines?

    <p>Antigenic variation refers to the ability of pathogens to change their surface antigens, making them difficult to be recognized by the immune system. This is important for vaccines because they need to target the right variant of the pathogen to be effective.</p> Signup and view all the answers

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