Pathogenic Mechanisms of Diseases

Arms and breasts.

Lower limbs and genitalia.

Diffuse filarial lung disease.

<p>Immunologic hyper-responsiveness to microfilarial antigens.</p> Signup and view all the answers

<p>It leads to local destruction of microfilariae in the pulmonary vascular system.</p> Signup and view all the answers

<p>Diffuse interstitial lung disease.</p> Signup and view all the answers

<p>They stimulate an immune response in the host.</p> Signup and view all the answers

<p>The arms and breasts.</p> Signup and view all the answers

<p>The primary pathogenic mechanisms are mainly attributed to the adults of the disease.</p> Signup and view all the answers

<p>Microfilariae seem to have no pathogenic manifestations despite being associated with the disease.</p> Signup and view all the answers

<p>Granulomatous inflammation is associated with microfilariae, particularly affecting the lungs, liver, and spleen.</p> Signup and view all the answers

<p>The lungs, liver, and spleen are primarily affected by granulomatous inflammation associated with this disease.</p> Signup and view all the answers

<p>Granulomatous inflammation manifests as a chronic inflammatory response in affected organs.</p> Signup and view all the answers

<p>Microfilariae are not pathogenic by themselves, but they can trigger granulomatous inflammation.</p> Signup and view all the answers

<p>Adult forms are primarily responsible for the pathogenic mechanisms, leading to various disease manifestations.</p> Signup and view all the answers

<p>Understanding this role can facilitate targeted therapies aimed at modulating the immune response to reduce inflammation.</p> Signup and view all the answers

<p>Common symptoms include fever, chills, headache, vomiting, and malaise.</p> Signup and view all the answers

<p>Leucocytosis and eosinophilia are typically observed.</p> Signup and view all the answers

<p>Fibrosis leads to changes in lymphatic structure, causing obstruction and dysfunction.</p> Signup and view all the answers

<p>Complications can include hydrocele, scrotal lymphoedema, and lymphatic varices.</p> Signup and view all the answers

<p>Coiled worms can cause inflammatory fibrosis which leads to chronic obstruction in lymphatics.</p> Signup and view all the answers

<p>In the groin, symptoms may be more pronounced due to nearby structures and lymphatic drainage.</p> Signup and view all the answers

<p>Eosinophilia can indicate allergic reactions or parasitic infections contributing to inflammation.</p> Signup and view all the answers

<p>Endothelial proliferation contributes to lymphatic obstruction and can result in dilated lymphatics.</p> Signup and view all the answers