Parkinson's Disease Overview
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Parkinson's Disease Overview

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Questions and Answers

What is the true etiology of Parkinson's disease?

  • Reduced activation of dopamine and dopamine receptors (correct)
  • Antagonism of adenosine A receptors in GABAergic neurons
  • Presence of Lewy bodies in the substantia nigra pars compacta
  • Loss of neurons in the substantia nigra pars compacta
  • What results in greater inhibition of the thalamus and reduced motor cortex activation in Parkinson's disease?

  • Reduced activation of dopamine and dopamine receptors (correct)
  • Antagonism of adenosine A receptors in GABAergic neurons
  • Loss of neurons in the substantia nigra pars compacta
  • Presence of Lewy bodies in the substantia nigra pars compacta
  • What can prolong dopaminergic action in Parkinson's disease?

  • Reduced activation of dopamine and dopamine receptors
  • Antagonism of adenosine A receptors in GABAergic neurons (correct)
  • Loss of neurons in the substantia nigra pars compacta
  • Presence of Lewy bodies in the substantia nigra pars compacta
  • What are the two hallmark features in the substantia nigra pars compacta in Parkinson's disease?

    <p>Loss of neurons and the presence of Lewy bodies</p> Signup and view all the answers

    What correlates positively with the severity of motor symptoms in Parkinson's disease?

    <p>Degree of nigrostriatal dopamine loss</p> Signup and view all the answers

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