Parkinson's Disease and Huntington's Disease Introduction

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Questions and Answers

What is the cause of neuronal death in the Substantia Niagra in Parkinson's Disease?

  • Oxidative stress and exposure to toxins
  • Excessive production of dopamine
  • Mutation of the Parkin gene (correct)
  • Degeneration of the Basal Ganglia

How is Parkinson's Disease treated?

  • Dopaminergic drugs to compensate for deficient dopamine secretion (correct)
  • Surgical removal of damaged neurons in the Substantia Niagra
  • Inhibition of dopamine production in the Basal Ganglia
  • Administration of excessive dopamine to reverse neuronal damage

What coincides with the industrial age and may contribute to the relatively new emergence of Parkinson's Disease?

  • High exposure to pesticides and toxins (correct)
  • Genetic mutations passed down through generations
  • Increased consumption of processed foods
  • Advancements in medical technology

What role do dopaminergic drugs play in treating Parkinson's Disease?

<p>Compensate for deficient dopamine secretion by the Substantia Niagra (A)</p> Signup and view all the answers

What is the main difference between the movement circuitry in Parkinson's Disease and Huntington's Disease?

<p>Parkinson's movement circuitry is stuck in the OFF mode, while Huntington's movement circuitry is always ON (A)</p> Signup and view all the answers

What is the main concern regarding gene replacement therapy for Parkinson's Disease?

<p>It involves the use of viral vectors which can be unpredictable (D)</p> Signup and view all the answers

What is the function of dopamine agonists in treating Parkinson's Disease?

<p>Compensate for deficient production of dopamine by the substantia niagra (A)</p> Signup and view all the answers

Why are stem cells controversial in treating Parkinson's Disease?

<p>They were initially derived from aborted fetuses (D)</p> Signup and view all the answers

How does deep-brain stimulation work in treating Parkinson's Disease?

<p>By modulating abnormal neural activity within specific brain regions (C)</p> Signup and view all the answers

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