9 Questions
What is the cause of neuronal death in the Substantia Niagra in Parkinson's Disease?
Mutation of the Parkin gene
How is Parkinson's Disease treated?
Dopaminergic drugs to compensate for deficient dopamine secretion
What coincides with the industrial age and may contribute to the relatively new emergence of Parkinson's Disease?
High exposure to pesticides and toxins
What role do dopaminergic drugs play in treating Parkinson's Disease?
Compensate for deficient dopamine secretion by the Substantia Niagra
What is the main difference between the movement circuitry in Parkinson's Disease and Huntington's Disease?
Parkinson's movement circuitry is stuck in the OFF mode, while Huntington's movement circuitry is always ON
What is the main concern regarding gene replacement therapy for Parkinson's Disease?
It involves the use of viral vectors which can be unpredictable
What is the function of dopamine agonists in treating Parkinson's Disease?
Compensate for deficient production of dopamine by the substantia niagra
Why are stem cells controversial in treating Parkinson's Disease?
They were initially derived from aborted fetuses
How does deep-brain stimulation work in treating Parkinson's Disease?
By modulating abnormal neural activity within specific brain regions
This quiz covers an introduction to Parkinson's disease, highlighting its impact on movement and the role of dopamine production in the Basal Ganglia. The text also briefly mentions Michael J. Fox's experience with Parkinson's. Additionally, it hints at the genetic mutation associated with the damage to the Substantia Niagra.
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