12 Questions
Which neurotransmitters are imbalanced in Parkinson disease?
Dopamine and acetylcholine
What is the primary region of the brain where neuron loss occurs in Parkinson disease?
Substantia nigra
What are the cardinal symptoms of Parkinson disease?
Rigidity, tremors, gait disturbance, and bradykinesia
Which neurotransmitter deficiency is associated with Alzheimer disease?
Acetylcholine
What type of drugs can induce parkinsonism and extrapyramidal symptoms?
Neuroleptic drugs (antipsychotics and dopamine receptor blockers)
What nonpharmacologic measures can help lessen symptoms of parkinsonism?
Patient teaching, exercise, nutrition, and group support
Why do patients with Parkinson disease experience symptomatic movement disorders?
Due to an imbalance between dopamine (DA) and acetylcholine (ACh)
What is the function of anticholinergic drugs in treating Parkinson disease?
Increase the effects of dopamine by reducing acetylcholine effects
What is an 'off' episode in Parkinson disease?
Time when symptoms worsen due to medication ineffectiveness
Which category of drugs used to treat Parkinson disease replaces the dopamine deficit directly?
Dopamine agonists
What is the main effect of anticholinergics on Parkinson disease symptoms?
Reduce rigidity and some tremors
Which neurotransmitter is primarily affected by the unexplained degeneration in Parkinson disease?
Dopamine (DA)
Learn about the chronic, progressive neurologic disorders Parkinson's disease and Alzheimer's disease, their symptoms, and possible causes. Discover how these disorders impact the extrapyramidal motor tract and cognitive function.
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