Parasympathetic System: Cholinergic Agonists

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

In which part of the brain are M4 muscarinic receptors primarily found?

  • Cerebellum
  • Cerebral cortex
  • Substantia nigra
  • Basal ganglia, amygdala, and hippocampus (correct)

What is the primary function of M2 receptors in the heart?

  • Decreasing heart rate and force of contraction (correct)
  • Stimulating salivary secretions
  • Regulating vasodilation
  • Increasing heart rate and force of contraction

Which of the following is NOT a location where muscarinic receptors are found?

  • Endothelial cells
  • Skeletal muscle (correct)
  • Autonomic ganglia
  • Neuro-effector junction

What is the primary mechanism of action of acetylcholine in the parasympathetic nervous system?

<p>Binding to muscarinic receptors (B)</p> Signup and view all the answers

Where are nicotinic receptors primarily found?

<p>All of the above (D)</p> Signup and view all the answers

What is the effect of acetylcholine on heart rate?

<p>Decreases heart rate (B)</p> Signup and view all the answers

Which of the following is an effect of M3 muscarinic receptors?

<p>Increased salivary secretions and motility (C)</p> Signup and view all the answers

What is the primary mechanism of acetylcholine signal transduction?

<p>Stimulation of 2nd messenger (D)</p> Signup and view all the answers

What is the duration of action of neostigmine?

<p>4-8 hours (A)</p> Signup and view all the answers

What is the action of Echothiophate?

<p>Irreversible inhibitor of acetylcholinesterase (C)</p> Signup and view all the answers

What is the therapeutic use of Pyridostigmine?

<p>Myasthenia gravis and antidote for tubocurarine (A)</p> Signup and view all the answers

What is the mechanism of action of Pralidoxime?

<p>Reactivation of acetylcholinesterase (D)</p> Signup and view all the answers

What is the common side effect of muscarinic agonists?

<p>All of the above (D)</p> Signup and view all the answers

What is the therapeutic use of Tacrine, Donepezil, Rivastigmine, and Galantamine?

<p>Treatment of Alzheimer's disease (D)</p> Signup and view all the answers

What is the characteristic of synthetic organophosphate compounds?

<p>They are used as nerve gases (C)</p> Signup and view all the answers

What is the action of Demecarium?

<p>Similar to neostigmine (C)</p> Signup and view all the answers

What is the use of Edrophonium?

<p>Diagnosis of myasthenia gravis (C)</p> Signup and view all the answers

What is the adverse effect of muscarinic agonists?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following agents has a structurally related acetylcholine that is not destroyed by acetylcholinesterase?

<p>Bethanechol (C)</p> Signup and view all the answers

What is the primary mechanism of indirect-acting agents?

<p>They inhibit the breakdown of acetylcholine by acetylcholinesterase (D)</p> Signup and view all the answers

What is the primary therapeutic use of Pilocarpine?

<p>Ophthalmology (C)</p> Signup and view all the answers

What is the primary adverse effect of Carbachol?

<p>Bronchospasm (B)</p> Signup and view all the answers

Which of the following agents stimulates the release of epinephrine from the adrenal medulla?

<p>Carbachol (A)</p> Signup and view all the answers

What is the primary application of Bethanechol?

<p>Urology (B)</p> Signup and view all the answers

What is the primary action of Physostigmine?

<p>Inhibits acetylcholinesterase (B)</p> Signup and view all the answers

What is the primary adverse effect of Pilocarpine?

<p>Body odor (A)</p> Signup and view all the answers

What is the primary difference between direct-acting and indirect-acting agents?

<p>Direct-acting agents stimulate receptors directly, while indirect-acting agents influence the metabolism of acetylcholine (C)</p> Signup and view all the answers

Flashcards are hidden until you start studying

Related Documents

Pharm Exam 2 PDF

More Like This

Use Quizgecko on...
Browser
Browser