Parasympathetic System: Cholinergic Agonists
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Questions and Answers

What is the primary neurotransmitter of the Cholinergic Neuron?

  • Dopamine
  • Acetylcholine (correct)
  • Serotonin
  • GABA
  • Where are Muscarinic Receptors primarily found?

  • Neuro-effector junction of the Parasympathetic nervous system (correct)
  • Somatic nervous system
  • Sensory organs
  • Sympathetic nervous system
  • What is the function of M2 receptors in the heart?

  • Stimulate the release of adrenaline
  • Inhibit the release of acetylcholine
  • Increase heart rate and force of contraction
  • Decrease heart rate and force of contraction (correct)
  • What is the result of Acetylcholine binding to Muscarinic Receptors?

    <p>Increased intracellular [Ca] and activation of 2nd messenger</p> Signup and view all the answers

    Which of the following is associated with Nicotinic Receptors?

    <p>CNS and Adrenal medulla</p> Signup and view all the answers

    What is the location of M4 receptors?

    <p>Basal ganglia, amygdala, hippocampus</p> Signup and view all the answers

    What is the primary effect of acetylcholine on the heart rate?

    <p>Decrease heart rate</p> Signup and view all the answers

    What is the primary therapeutic use of pilocarpine?

    <p>Treatment of open-angle glaucoma</p> Signup and view all the answers

    What is the mechanism of action of indirect acting agents?

    <p>Inhibition of acetylcholinesterase</p> Signup and view all the answers

    What is the therapeutic use of physostigmine?

    <p>Treatment of atony of intestines and bladder</p> Signup and view all the answers

    What is the duration of action of pyridostigmine?

    <p>3-6 hours</p> Signup and view all the answers

    What is the primary adverse effect of neostigmine?

    <p>Convulsions</p> Signup and view all the answers

    What is the therapeutic use of tacrine?

    <p>Treatment of Alzheimer's disease</p> Signup and view all the answers

    What is the effect of echothiophate on acetylcholinesterase?

    <p>Irreversible inhibition</p> Signup and view all the answers

    What is the primary use of pralidoxime?

    <p>Treatment of organo-phosphate poisoning</p> Signup and view all the answers

    What is the common side effect of muscarinic agonists?

    <p>Diarrhea</p> Signup and view all the answers

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