Papulosquamous Diseases and Pathology Quiz

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Which treatment modality is most appropriate for the patient with papulosquamous diseases as described in the text?

Erythromycin

Tacrolimus

Steroid

Phototherapy (correct)

Which histopathological feature is characteristic of PLEVA (pityriasis lichenoides et varioliformis acuta)?

More parakeratosis and epidermal destruction

Necrotic keratinocytes and extravasated RBCs (correct)

Wedge focal parakeratosis and spongiosis

Perivascular interface dermatitis

If a patient on NBUVB (narrowband UVB) therapy stops the session for 1 week, what is the recommended next step?

Continue

Increase dose (correct)

Decrease dose

Switch to a different treatment modality

What is the causative drug commonly associated with the development of asymptomatic nodules in a patient with rheumatoid arthritis?

Methotrexate (MTX) Signup and view all the answers

What is the most appropriate treatment for psoriasis in a child?

NBUVB therapy Signup and view all the answers

In a patient with lesions (mostly psoriasis) and without insurance coverage, which treatment modality would be most suitable?

Methotrexate (MTX) Signup and view all the answers

In a patient with dark brown multiple annular plaques, what is the most common site for this presentation?

Groin Signup and view all the answers

Which drug is most likely to cause lichenoid drug eruptions in a patient with hypertension?

Captopril Signup and view all the answers

In a patient with tiny skin colored papules on the hand resembling lichen nitidus, what is the commonest other site for this presentation?

Face Signup and view all the answers

What is the next step if a patient with rheumatoid arthritis develops asymptomatic nodules while on adalimumab treatment?

Discontinue adalimumab and start TNF alpha inhibitor Signup and view all the answers

Which treatment modality is commonly used for the management of lichen planus affecting the oral mucosa?

Tacrolimus Signup and view all the answers

In a patient with psoriatic nails and palm, what is the recommended treatment if all nails are affected?

Biological therapy Signup and view all the answers

In a female patient taking biologic treatment for 4 years with improvement, then presenting with scaly erythematous plaque and normal breast cancer investigations, what is the recommended next step?

Watch Signup and view all the answers

In a case of knee with small tiny papules as L. nitidus associated with papules on wrist, what is the HLA marker of this disease?

HLA-ABC Signup and view all the answers

In a psoriasis patient taking biologic treatment and presenting with bloody stool, which type of biologic treatment could be responsible for causing this symptom?

Secukinumab Signup and view all the answers

In a patient with bloody diarrhea after taking secukinumab, what is the next recommended investigation?

Colonoscopy Signup and view all the answers

In a 34-year-old patient with plaque psoriasis, what is the most effective treatment?

PUVA Signup and view all the answers

What is the most likely diagnosis for localized scales in the scalp beside the ear with no hair loss and erythema?

Psoriasis if pityriasis amiantacea Signup and view all the answers

In a patient with periumbilical umbilicated papules resembling molluscum and presenting with weight loss and CD4 count less than 200, what investigation is indicated?

PET scan if submandibular gland nodule present to search for primary tumor Signup and view all the answers

What is the most suitable treatment for a patient with atopic dermatitis?

NBUVB Signup and view all the answers

In a patient with renal transplantation who develops a maculopapular rash all over the body after 1 year, which virus is most likely responsible?

Polyomavirus Signup and view all the answers

What period of preconception in weeks should be considered for a case of PRP?

6 weeks Signup and view all the answers

What is the most appropriate treatment for a patient with multiple erythematous plaques, scaly papules, and no joint pain or itching for 3 months?

Acitretin Signup and view all the answers

In a female patient with controlled psoriasis on biological therapy who is diagnosed with breast cancer, what is the appropriate next step?

Watch and wait Signup and view all the answers

In a patient with eruptive skin papules on the trunk and chest with a thread-like border, which condition should be considered?

Precancerous Signup and view all the answers

What is the appropriate treatment for pityriasis rubra pilaris (PRP)?

Retinoids Signup and view all the answers

What is the histopathology typically seen in porokeratosis of Mibelli?

Parakeratosis and underlying hypogranulosis Signup and view all the answers

In a patient with scleroderma-like lesions on the hand and knee, palmoplantar hyperkeratosis, and histopathological findings suggestive of porokeratosis, what is the most likely association?

An inflammatory condition Signup and view all the answers

In a female patient with pityriasis rotunda, what neoplasm should be considered as an associated risk?

Gastric cancer Signup and view all the answers

In a female patient with Bazex syndrome (scaly plaques on hands & feet, nose & ear involvement), what neoplasm should be considered as an associated risk?

Lung cancer Signup and view all the answers

What is the most appropriate treatment for a patient with asymptomatic erythematous plaques covering >50% of body surface area and no back pain?

Narrowband UVB phototherapy Signup and view all the answers

In a patient with plaque psoriasis and congestive heart failure living 100km away from the hospital, what is the best treatment option?

Phototherapy Signup and view all the answers

In an adult female with skin-colored papules with induration on the face, trunk, and thighs (scleromyxedema), what would be the most appropriate treatment option?

Thalidomide Signup and view all the answers

In a patient with known renal failure and generalized itchy hyperpigmented lesions resembling atrophic lichen planus, what would be the most appropriate treatment?

Narrowband UVB phototherapy Signup and view all the answers

Which treatment modality is most suitable for a patient with papulosquamous diseases and no insurance coverage?

UV therapy Signup and view all the answers

In a patient with eruptive skin papules on the trunk and chest with a thread-like border, which condition should be considered?

Pityriasis rosea Signup and view all the answers

In a patient with tiny skin colored papules on the hand resembling lichen nitidus, what is the commonest other site for this presentation?

Genitalia Signup and view all the answers

What is the most common site for dark brown multiple annular plaques in a patient?

Groin Signup and view all the answers

If a patient on NBUVB (narrowband UVB) therapy stops the session for 1 week, what is the recommended next step?

Increase dose Signup and view all the answers

In a patient with rheumatoid arthritis who developed asymptomatic nodules on the elbow and knee, which drug is most likely responsible?

Methotrexate Signup and view all the answers

What is the most appropriate treatment for a patient with palmoplantar hyperkeratosis, hypopigmented lesions, and scaly erythematous papules?

Acitretin Signup and view all the answers

In a female child with asymptomatic erythematous plaques covering more than 50% of the body surface area and no back pain, what is the recommended treatment for psoriasis?

Narrowband UVB Signup and view all the answers

What is the best treatment option for a patient with plaque psoriasis and congestive heart failure living 100km away from the hospital?

Phototherapy Signup and view all the answers

What would be the most appropriate treatment for a 35-year-old adult female with skin-colored papules, induration on the face, trunk, and thighs (scleromyxodema), and no IVIG administration?

Thalidomide Signup and view all the answers

In a patient taking biologic treatment for 4 years with improvement, then presenting with scaly erythematous plaque and normal breast cancer investigations, what is the recommended next step?

MTX Signup and view all the answers

What is the HLA marker of the disease associated with small tiny papules on the knee and wrist?

HLA-ABC Signup and view all the answers

What type of keratin is associated with PPK trans gradient?

Keratin 10 Signup and view all the answers

In a patient with localized scales in the scalp beside the ear, with no hair loss and erythema, what is the most likely diagnosis?

Seborrheic dermatitis Signup and view all the answers

What is the histopathology typically seen in lichen planus of the nail?

Keratinocyte necrosis Signup and view all the answers

In a patient taking biologic treatment who presents with bloody stool, which type of biologic treatment could be responsible for causing this symptom?

Secukinumab Signup and view all the answers

In a patient with renal transplantation who develops a maculopapular rash all over the body after 1 year, which virus is most likely responsible?

Polyoma Signup and view all the answers

Which epidermal differentiated keratinocytes are typically associated with K1,10?

K1,10 Signup and view all the answers

What is the appropriate treatment for a patient with known renal failure and generalized itching, hyperpigmentation?

NBUVB Signup and view all the answers

In a patient with plaque psoriasis controlled on infliximab then becomes uncontrolled on infliximab, what is the next step (secondary failure)?

Shift to another biologic Signup and view all the answers

In a psoriatic patient taking biologic treatment and presenting with bloody stool, which type of biologic treatment could be responsible for causing this symptom?

Secukinumab & ixekizumab & brodalimumab Signup and view all the answers

In a female patient on certolizumab who becomes pregnant, what is the recommended action?

Stop Signup and view all the answers

Which treatment modality is most appropriate for the management of a patient with asymptomatic nodules on the elbow and knee caused by rheumatoid arthritis?

Methotrexate Signup and view all the answers

If a patient with rheumatoid arthritis develops asymptomatic nodules on the elbow and knee, which drug is most likely responsible?

Methotrexate Signup and view all the answers

In a patient with dark brown multiple annular plaques, what is the most common site for this presentation?

Leg if pityriasis rotunda Signup and view all the answers

What is the next step if a patient on NBUVB (narrowband UVB) therapy stops the session for 1 week?

Increase dose Signup and view all the answers

A patient with rheumatoid arthritis developed asymptomatic nodules on the elbow and knee. What is the causative drug?

Methotrexate Signup and view all the answers

What would be the most appropriate treatment for a child with psoriasis?

NBUVB Signup and view all the answers

In a patient with lesions (mostly psoriasis) and without insurance coverage, which treatment modality would be most suitable?

Methotrexate Signup and view all the answers

What is the commonest other site for tiny skin colored papules as lichen nitidus, apart from the hand?

Face Signup and view all the answers

If a patient with papulosquamous diseases stopped NBUVB therapy for 1 week, what is the recommended next step?

Increase dose Signup and view all the answers

In a patient with hypertension and lichenoid drug eruptions, what is the causative drug?

Captopril Signup and view all the answers

A patient with rheumatoid arthritis developed asymptomatic nodules on the elbow and knee. What would be the most effective treatment?

Methotrexate Signup and view all the answers

What is the causative drug commonly associated with the development of asymptomatic nodules in a patient with rheumatoid arthritis?

Methotrexate Signup and view all the answers

Which investigation is indicated for an old male patient with MF histopathology showing Partueir microabscess and CT scan with LN enlargement?

T cell receptor rearrangement in tissue Signup and view all the answers

What is the FDA approved drug for a case scenario of MF cd 30 positive?

Brentuximab Signup and view all the answers

In a patient with asymptomatic erythematous plaques covering more than 50% of the body surface area and no back pain, what is the recommended treatment for psoriasis?

Narrowband Signup and view all the answers

For an adult female with skin-colored papules with induration on the face, trunk, and thighs (scleromyxedema), what would be the treatment option?

IVIG Signup and view all the answers

In a patient with eruptive skin papules on the trunk and chest with thread-like border (porokeratosis or seborrheic keratosis), what condition should be considered?

Precancerous Signup and view all the answers

What is the characteristic histopathology of porokeratosis of Mabili?

Parakeratosis and underlying hypergranulosis Signup and view all the answers

Which type of keratin is associated with PPK (palmoplantar keratoderma)?

Type 4 Signup and view all the answers

In the picture of nail psoriasis, what type of associated disease is indicated?

Arthritis Signup and view all the answers

In the case of a female patient taking biologic treatment for 4 years with improvement, then presenting with scaly erythematous plaque and normal breast cancer investigations, what is the recommended next step?

Watch Signup and view all the answers

If a patient taking biologic treatment experiences bloody stool, which type of biologic treatment could be responsible?

Secukinumab Signup and view all the answers

In a patient with renal transplantation who develops a maculopapular rash all over the body, which virus is most likely involved?

Polyoma Signup and view all the answers

In a patient with lichen planus involving the nails, what is the typical histopathology?

Hypergranulosis Signup and view all the answers

In a patient with periumbilical umbilicated papules resembling molluscum and presenting with weight loss and CD4 count less than 200, what investigation is indicated?

(PET) scan if SMJ nodule to search for primary tumor. Signup and view all the answers

What is the most effective treatment of plaque psoriasis in a 34-year-old patient?

(PUVA) Signup and view all the answers

In a case of localized scales in the scalp beside the ear with no hair loss and erythema, what is the most likely diagnosis?

(Psoriasis) if pityriasis amentia Signup and view all the answers

(LP) Lichen planus case histopathology is characterized by:

(Hypergranulosis) Signup and view all the answers

For patients with GVHD (chronic type), what biologic treatment is recommended?

Anti CD20: rituximab Signup and view all the answers

What epidermal differentiated keratinocytes are typically associated with K1,10?

K1,10 Signup and view all the answers

Papulosquamous Diseases and Pathology Quiz

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Questions and Answers

Which treatment modality is most appropriate for the patient with papulosquamous diseases as described in the text?

Which histopathological feature is characteristic of PLEVA (pityriasis lichenoides et varioliformis acuta)?

If a patient on NBUVB (narrowband UVB) therapy stops the session for 1 week, what is the recommended next step?

What is the causative drug commonly associated with the development of asymptomatic nodules in a patient with rheumatoid arthritis?

What is the most appropriate treatment for psoriasis in a child?

In a patient with lesions (mostly psoriasis) and without insurance coverage, which treatment modality would be most suitable?

In a patient with dark brown multiple annular plaques, what is the most common site for this presentation?

Which drug is most likely to cause lichenoid drug eruptions in a patient with hypertension?

In a patient with tiny skin colored papules on the hand resembling lichen nitidus, what is the commonest other site for this presentation?

What is the next step if a patient with rheumatoid arthritis develops asymptomatic nodules while on adalimumab treatment?

Which treatment modality is commonly used for the management of lichen planus affecting the oral mucosa?

In a patient with psoriatic nails and palm, what is the recommended treatment if all nails are affected?

In a female patient taking biologic treatment for 4 years with improvement, then presenting with scaly erythematous plaque and normal breast cancer investigations, what is the recommended next step?

In a case of knee with small tiny papules as L. nitidus associated with papules on wrist, what is the HLA marker of this disease?

In a psoriasis patient taking biologic treatment and presenting with bloody stool, which type of biologic treatment could be responsible for causing this symptom?

In a patient with bloody diarrhea after taking secukinumab, what is the next recommended investigation?

In a 34-year-old patient with plaque psoriasis, what is the most effective treatment?

What is the most likely diagnosis for localized scales in the scalp beside the ear with no hair loss and erythema?

In a patient with periumbilical umbilicated papules resembling molluscum and presenting with weight loss and CD4 count less than 200, what investigation is indicated?

What is the most suitable treatment for a patient with atopic dermatitis?

In a patient with renal transplantation who develops a maculopapular rash all over the body after 1 year, which virus is most likely responsible?

What period of preconception in weeks should be considered for a case of PRP?

What is the most appropriate treatment for a patient with multiple erythematous plaques, scaly papules, and no joint pain or itching for 3 months?

In a female patient with controlled psoriasis on biological therapy who is diagnosed with breast cancer, what is the appropriate next step?

In a patient with eruptive skin papules on the trunk and chest with a thread-like border, which condition should be considered?

What is the appropriate treatment for pityriasis rubra pilaris (PRP)?

What is the histopathology typically seen in porokeratosis of Mibelli?

In a patient with scleroderma-like lesions on the hand and knee, palmoplantar hyperkeratosis, and histopathological findings suggestive of porokeratosis, what is the most likely association?

In a female patient with pityriasis rotunda, what neoplasm should be considered as an associated risk?

In a female patient with Bazex syndrome (scaly plaques on hands & feet, nose & ear involvement), what neoplasm should be considered as an associated risk?

What is the most appropriate treatment for a patient with asymptomatic erythematous plaques covering >50% of body surface area and no back pain?

In a patient with plaque psoriasis and congestive heart failure living 100km away from the hospital, what is the best treatment option?

In an adult female with skin-colored papules with induration on the face, trunk, and thighs (scleromyxedema), what would be the most appropriate treatment option?

In a patient with known renal failure and generalized itchy hyperpigmented lesions resembling atrophic lichen planus, what would be the most appropriate treatment?

Which treatment modality is most suitable for a patient with papulosquamous diseases and no insurance coverage?

In a patient with eruptive skin papules on the trunk and chest with a thread-like border, which condition should be considered?

In a patient with tiny skin colored papules on the hand resembling lichen nitidus, what is the commonest other site for this presentation?

What is the most common site for dark brown multiple annular plaques in a patient?

If a patient on NBUVB (narrowband UVB) therapy stops the session for 1 week, what is the recommended next step?

In a patient with rheumatoid arthritis who developed asymptomatic nodules on the elbow and knee, which drug is most likely responsible?

What is the most appropriate treatment for a patient with palmoplantar hyperkeratosis, hypopigmented lesions, and scaly erythematous papules?

In a female child with asymptomatic erythematous plaques covering more than 50% of the body surface area and no back pain, what is the recommended treatment for psoriasis?

What is the best treatment option for a patient with plaque psoriasis and congestive heart failure living 100km away from the hospital?

What would be the most appropriate treatment for a 35-year-old adult female with skin-colored papules, induration on the face, trunk, and thighs (scleromyxodema), and no IVIG administration?

In a patient taking biologic treatment for 4 years with improvement, then presenting with scaly erythematous plaque and normal breast cancer investigations, what is the recommended next step?

What is the HLA marker of the disease associated with small tiny papules on the knee and wrist?

What type of keratin is associated with PPK trans gradient?

In a patient with localized scales in the scalp beside the ear, with no hair loss and erythema, what is the most likely diagnosis?

What is the histopathology typically seen in lichen planus of the nail?

In a patient taking biologic treatment who presents with bloody stool, which type of biologic treatment could be responsible for causing this symptom?

In a patient with renal transplantation who develops a maculopapular rash all over the body after 1 year, which virus is most likely responsible?

Which epidermal differentiated keratinocytes are typically associated with K1,10?

What is the appropriate treatment for a patient with known renal failure and generalized itching, hyperpigmentation?

In a patient with plaque psoriasis controlled on infliximab then becomes uncontrolled on infliximab, what is the next step (secondary failure)?

In a psoriatic patient taking biologic treatment and presenting with bloody stool, which type of biologic treatment could be responsible for causing this symptom?

In a female patient on certolizumab who becomes pregnant, what is the recommended action?

Which treatment modality is most appropriate for the management of a patient with asymptomatic nodules on the elbow and knee caused by rheumatoid arthritis?

If a patient with rheumatoid arthritis develops asymptomatic nodules on the elbow and knee, which drug is most likely responsible?

In a patient with dark brown multiple annular plaques, what is the most common site for this presentation?

What is the next step if a patient on NBUVB (narrowband UVB) therapy stops the session for 1 week?

A patient with rheumatoid arthritis developed asymptomatic nodules on the elbow and knee. What is the causative drug?

What would be the most appropriate treatment for a child with psoriasis?

In a patient with lesions (mostly psoriasis) and without insurance coverage, which treatment modality would be most suitable?

What is the commonest other site for tiny skin colored papules as lichen nitidus, apart from the hand?

If a patient with papulosquamous diseases stopped NBUVB therapy for 1 week, what is the recommended next step?

In a patient with hypertension and lichenoid drug eruptions, what is the causative drug?

A patient with rheumatoid arthritis developed asymptomatic nodules on the elbow and knee. What would be the most effective treatment?

What is the causative drug commonly associated with the development of asymptomatic nodules in a patient with rheumatoid arthritis?

Which investigation is indicated for an old male patient with MF histopathology showing Partueir microabscess and CT scan with LN enlargement?

What is the FDA approved drug for a case scenario of MF cd 30 positive?

In a patient with asymptomatic erythematous plaques covering more than 50% of the body surface area and no back pain, what is the recommended treatment for psoriasis?

For an adult female with skin-colored papules with induration on the face, trunk, and thighs (scleromyxedema), what would be the treatment option?

In a patient with eruptive skin papules on the trunk and chest with thread-like border (porokeratosis or seborrheic keratosis), what condition should be considered?

What is the characteristic histopathology of porokeratosis of Mabili?

Which type of keratin is associated with PPK (palmoplantar keratoderma)?

In the picture of nail psoriasis, what type of associated disease is indicated?

In the case of a female patient taking biologic treatment for 4 years with improvement, then presenting with scaly erythematous plaque and normal breast cancer investigations, what is the recommended next step?