86 Questions
Which treatment modality is most appropriate for the patient with papulosquamous diseases as described in the text?
Phototherapy
Which histopathological feature is characteristic of PLEVA (pityriasis lichenoides et varioliformis acuta)?
Necrotic keratinocytes and extravasated RBCs
If a patient on NBUVB (narrowband UVB) therapy stops the session for 1 week, what is the recommended next step?
Increase dose
What is the causative drug commonly associated with the development of asymptomatic nodules in a patient with rheumatoid arthritis?
Methotrexate (MTX)
What is the most appropriate treatment for psoriasis in a child?
NBUVB therapy
In a patient with lesions (mostly psoriasis) and without insurance coverage, which treatment modality would be most suitable?
Methotrexate (MTX)
In a patient with dark brown multiple annular plaques, what is the most common site for this presentation?
Groin
Which drug is most likely to cause lichenoid drug eruptions in a patient with hypertension?
Captopril
In a patient with tiny skin colored papules on the hand resembling lichen nitidus, what is the commonest other site for this presentation?
Face
What is the next step if a patient with rheumatoid arthritis develops asymptomatic nodules while on adalimumab treatment?
Discontinue adalimumab and start TNF alpha inhibitor
Which treatment modality is commonly used for the management of lichen planus affecting the oral mucosa?
Tacrolimus
In a patient with psoriatic nails and palm, what is the recommended treatment if all nails are affected?
Biological therapy
In a female patient taking biologic treatment for 4 years with improvement, then presenting with scaly erythematous plaque and normal breast cancer investigations, what is the recommended next step?
Watch
In a case of knee with small tiny papules as L. nitidus associated with papules on wrist, what is the HLA marker of this disease?
HLA-ABC
In a psoriasis patient taking biologic treatment and presenting with bloody stool, which type of biologic treatment could be responsible for causing this symptom?
Secukinumab
In a patient with bloody diarrhea after taking secukinumab, what is the next recommended investigation?
Colonoscopy
In a 34-year-old patient with plaque psoriasis, what is the most effective treatment?
PUVA
What is the most likely diagnosis for localized scales in the scalp beside the ear with no hair loss and erythema?
Psoriasis if pityriasis amiantacea
In a patient with periumbilical umbilicated papules resembling molluscum and presenting with weight loss and CD4 count less than 200, what investigation is indicated?
PET scan if submandibular gland nodule present to search for primary tumor
What is the most suitable treatment for a patient with atopic dermatitis?
NBUVB
In a patient with renal transplantation who develops a maculopapular rash all over the body after 1 year, which virus is most likely responsible?
Polyomavirus
What period of preconception in weeks should be considered for a case of PRP?
6 weeks
What is the most appropriate treatment for a patient with multiple erythematous plaques, scaly papules, and no joint pain or itching for 3 months?
Acitretin
In a female patient with controlled psoriasis on biological therapy who is diagnosed with breast cancer, what is the appropriate next step?
Watch and wait
In a patient with eruptive skin papules on the trunk and chest with a thread-like border, which condition should be considered?
Precancerous
What is the appropriate treatment for pityriasis rubra pilaris (PRP)?
Retinoids
What is the histopathology typically seen in porokeratosis of Mibelli?
Parakeratosis and underlying hypogranulosis
In a patient with scleroderma-like lesions on the hand and knee, palmoplantar hyperkeratosis, and histopathological findings suggestive of porokeratosis, what is the most likely association?
An inflammatory condition
In a female patient with pityriasis rotunda, what neoplasm should be considered as an associated risk?
Gastric cancer
In a female patient with Bazex syndrome (scaly plaques on hands & feet, nose & ear involvement), what neoplasm should be considered as an associated risk?
Lung cancer
What is the most appropriate treatment for a patient with asymptomatic erythematous plaques covering >50% of body surface area and no back pain?
Narrowband UVB phototherapy
In a patient with plaque psoriasis and congestive heart failure living 100km away from the hospital, what is the best treatment option?
Phototherapy
In an adult female with skin-colored papules with induration on the face, trunk, and thighs (scleromyxedema), what would be the most appropriate treatment option?
Thalidomide
In a patient with known renal failure and generalized itchy hyperpigmented lesions resembling atrophic lichen planus, what would be the most appropriate treatment?
Narrowband UVB phototherapy
Which treatment modality is most suitable for a patient with papulosquamous diseases and no insurance coverage?
UV therapy
In a patient with eruptive skin papules on the trunk and chest with a thread-like border, which condition should be considered?
Pityriasis rosea
In a patient with tiny skin colored papules on the hand resembling lichen nitidus, what is the commonest other site for this presentation?
Genitalia
What is the most common site for dark brown multiple annular plaques in a patient?
Groin
If a patient on NBUVB (narrowband UVB) therapy stops the session for 1 week, what is the recommended next step?
Increase dose
In a patient with rheumatoid arthritis who developed asymptomatic nodules on the elbow and knee, which drug is most likely responsible?
Methotrexate
What is the most appropriate treatment for a patient with palmoplantar hyperkeratosis, hypopigmented lesions, and scaly erythematous papules?
Acitretin
In a female child with asymptomatic erythematous plaques covering more than 50% of the body surface area and no back pain, what is the recommended treatment for psoriasis?
Narrowband UVB
What is the best treatment option for a patient with plaque psoriasis and congestive heart failure living 100km away from the hospital?
Phototherapy
What would be the most appropriate treatment for a 35-year-old adult female with skin-colored papules, induration on the face, trunk, and thighs (scleromyxodema), and no IVIG administration?
Thalidomide
In a patient taking biologic treatment for 4 years with improvement, then presenting with scaly erythematous plaque and normal breast cancer investigations, what is the recommended next step?
MTX
What is the HLA marker of the disease associated with small tiny papules on the knee and wrist?
HLA-ABC
What type of keratin is associated with PPK trans gradient?
Keratin 10
In a patient with localized scales in the scalp beside the ear, with no hair loss and erythema, what is the most likely diagnosis?
Seborrheic dermatitis
What is the histopathology typically seen in lichen planus of the nail?
Keratinocyte necrosis
In a patient taking biologic treatment who presents with bloody stool, which type of biologic treatment could be responsible for causing this symptom?
Secukinumab
In a patient with renal transplantation who develops a maculopapular rash all over the body after 1 year, which virus is most likely responsible?
Polyoma
Which epidermal differentiated keratinocytes are typically associated with K1,10?
K1,10
What is the appropriate treatment for a patient with known renal failure and generalized itching, hyperpigmentation?
NBUVB
In a patient with plaque psoriasis controlled on infliximab then becomes uncontrolled on infliximab, what is the next step (secondary failure)?
Shift to another biologic
In a psoriatic patient taking biologic treatment and presenting with bloody stool, which type of biologic treatment could be responsible for causing this symptom?
Secukinumab & ixekizumab & brodalimumab
In a female patient on certolizumab who becomes pregnant, what is the recommended action?
Stop
Which treatment modality is most appropriate for the management of a patient with asymptomatic nodules on the elbow and knee caused by rheumatoid arthritis?
Methotrexate
If a patient with rheumatoid arthritis develops asymptomatic nodules on the elbow and knee, which drug is most likely responsible?
Methotrexate
In a patient with dark brown multiple annular plaques, what is the most common site for this presentation?
Leg if pityriasis rotunda
What is the next step if a patient on NBUVB (narrowband UVB) therapy stops the session for 1 week?
Increase dose
A patient with rheumatoid arthritis developed asymptomatic nodules on the elbow and knee. What is the causative drug?
Methotrexate
What would be the most appropriate treatment for a child with psoriasis?
NBUVB
In a patient with lesions (mostly psoriasis) and without insurance coverage, which treatment modality would be most suitable?
Methotrexate
What is the commonest other site for tiny skin colored papules as lichen nitidus, apart from the hand?
Face
If a patient with papulosquamous diseases stopped NBUVB therapy for 1 week, what is the recommended next step?
Increase dose
In a patient with hypertension and lichenoid drug eruptions, what is the causative drug?
Captopril
A patient with rheumatoid arthritis developed asymptomatic nodules on the elbow and knee. What would be the most effective treatment?
Methotrexate
What is the causative drug commonly associated with the development of asymptomatic nodules in a patient with rheumatoid arthritis?
Methotrexate
Which investigation is indicated for an old male patient with MF histopathology showing Partueir microabscess and CT scan with LN enlargement?
T cell receptor rearrangement in tissue
What is the FDA approved drug for a case scenario of MF cd 30 positive?
Brentuximab
In a patient with asymptomatic erythematous plaques covering more than 50% of the body surface area and no back pain, what is the recommended treatment for psoriasis?
Narrowband
For an adult female with skin-colored papules with induration on the face, trunk, and thighs (scleromyxedema), what would be the treatment option?
IVIG
In a patient with eruptive skin papules on the trunk and chest with thread-like border (porokeratosis or seborrheic keratosis), what condition should be considered?
Precancerous
What is the characteristic histopathology of porokeratosis of Mabili?
Parakeratosis and underlying hypergranulosis
Which type of keratin is associated with PPK (palmoplantar keratoderma)?
Type 4
In the picture of nail psoriasis, what type of associated disease is indicated?
Arthritis
In the case of a female patient taking biologic treatment for 4 years with improvement, then presenting with scaly erythematous plaque and normal breast cancer investigations, what is the recommended next step?
Watch
If a patient taking biologic treatment experiences bloody stool, which type of biologic treatment could be responsible?
Secukinumab
In a patient with renal transplantation who develops a maculopapular rash all over the body, which virus is most likely involved?
Polyoma
In a patient with lichen planus involving the nails, what is the typical histopathology?
Hypergranulosis
In a patient with periumbilical umbilicated papules resembling molluscum and presenting with weight loss and CD4 count less than 200, what investigation is indicated?
(PET) scan if SMJ nodule to search for primary tumor.
What is the most effective treatment of plaque psoriasis in a 34-year-old patient?
(PUVA)
In a case of localized scales in the scalp beside the ear with no hair loss and erythema, what is the most likely diagnosis?
(Psoriasis) if pityriasis amentia
(LP) Lichen planus case histopathology is characterized by:
(Hypergranulosis)
For patients with GVHD (chronic type), what biologic treatment is recommended?
Anti CD20: rituximab
What epidermal differentiated keratinocytes are typically associated with K1,10?
K1,10
Test your knowledge of papulosquamous diseases and their treatments. Identify the appropriate treatment for a patient with a papule and necrotic center, as well as the pathology features of PLEVA/PLC. Evaluate your understanding of different treatment options and pathological characteristics.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free