Papulosquamous Diseases Quiz
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Questions and Answers

Which histological sign is characteristic of psoriasis?

  • Lymphocytic infiltrate in the subcutaneous tissue
  • Accumulation of mast cells in the lower dermis
  • Presence of eosinophils in the epidermis
  • Capillary dilatation in the upper dermis (Auspitz sign) (correct)

Which variant of psoriasis is characterized by lesions the size of drops of water?

  • Nail psoriasis
  • Plaque psoriasis
  • Scalp psoriasis
  • Guttate psoriasis (correct)

Which clinical presentation is often associated with psoriasis?

  • Blistering and oozing of clear fluid
  • Hives-like wheals
  • Symmetrical redness and swelling of the joints
  • Sharply demarcated, erythematous papules and plaques often covered with silvery-white scales (correct)

What is the most common type of psoriasis affecting around 85% of patients?

<p>Plaque psoriasis (B)</p> Signup and view all the answers

What sign is observed when the covering scale is removed from a psoriatic lesion?

<p>Punctuate bleeding (Auspitz sign) (D)</p> Signup and view all the answers

Study Notes

Papulosquamous Diseases

  • Papulosquamous diseases include Psoriasis, Lichen planus, and Pityriasis Rubra pilaris

Psoriasis

  • Chronic skin disease with unpredictable remissions and relapses
  • Mostly affects adults between 14-40 years old
  • Incidence: 1-2% of population

Proactive Factors of Psoriasis

  • Genetic: Polygenic inheritance (PSORS1), 30% have positive family history
  • Genetic associations: HLA ass B13, BW17, CW6, B27
  • Trauma: Koebner phenomenon
  • Infection: Streptococcal infection
  • Weather: Worse in winter
  • Endocrine: Exacerbated by puberty, menopause, and pregnancy
  • Drug-induced: Antimalarials, withdrawal of steroids, Lithium, and propranolol
  • Emotional stress: 40% of cases
  • Lifestyle: Obesity, smoking, and alcoholism

Pathogenesis of Psoriasis

  • Stimulation: Trauma, infection, and other factors
  • Secretion: IL1, IL8, TNF alpha, interferon gamma, and IL2
  • Response: Epidermal hyperproliferation (4-5 days), parakeratosis, and scale formation

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Description

Test your knowledge of papulosquamous diseases with this quiz by Dr. Sahar Ahmed Al-Awdi from the Dermatology department at Sana'a University. Learn about psoriasis, lichen planus, and Pityriasis Rubra pilaris. Understand the factors that contribute to psoriasis and its impact on the population.

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