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Questions and Answers
Which histological sign is characteristic of psoriasis?
Which variant of psoriasis is characterized by lesions the size of drops of water?
Which clinical presentation is often associated with psoriasis?
What is the most common type of psoriasis affecting around 85% of patients?
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What sign is observed when the covering scale is removed from a psoriatic lesion?
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Study Notes
Papulosquamous Diseases
- Papulosquamous diseases include Psoriasis, Lichen planus, and Pityriasis Rubra pilaris
Psoriasis
- Chronic skin disease with unpredictable remissions and relapses
- Mostly affects adults between 14-40 years old
- Incidence: 1-2% of population
Proactive Factors of Psoriasis
- Genetic: Polygenic inheritance (PSORS1), 30% have positive family history
- Genetic associations: HLA ass B13, BW17, CW6, B27
- Trauma: Koebner phenomenon
- Infection: Streptococcal infection
- Weather: Worse in winter
- Endocrine: Exacerbated by puberty, menopause, and pregnancy
- Drug-induced: Antimalarials, withdrawal of steroids, Lithium, and propranolol
- Emotional stress: 40% of cases
- Lifestyle: Obesity, smoking, and alcoholism
Pathogenesis of Psoriasis
- Stimulation: Trauma, infection, and other factors
- Secretion: IL1, IL8, TNF alpha, interferon gamma, and IL2
- Response: Epidermal hyperproliferation (4-5 days), parakeratosis, and scale formation
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Description
Test your knowledge of papulosquamous diseases with this quiz by Dr. Sahar Ahmed Al-Awdi from the Dermatology department at Sana'a University. Learn about psoriasis, lichen planus, and Pityriasis Rubra pilaris. Understand the factors that contribute to psoriasis and its impact on the population.
