Podcast
Questions and Answers
What active enzymes are secreted by the acini in the pancreas?
What active enzymes are secreted by the acini in the pancreas?
- Pepsin and rennin
- Trypsin and chymotrypsin
- Amylase and lipase (correct)
- Amylase and pepsin
What type of infiltrates are found in the islets of Type 1 diabetes?
What type of infiltrates are found in the islets of Type 1 diabetes?
- Eosinophilic infiltrates
- Neutrophilic infiltrates
- Lymphocytic infiltrates (correct)
- Monocytic infiltrates
What do ductal cells in the pancreas release?
What do ductal cells in the pancreas release?
- Insulin and glucagon
- Trypsin and chymotrypsin
- Pepsin and rennin
- Bicarbonate and water (correct)
Approximately how much fluid is produced by the pancreas each day?
Approximately how much fluid is produced by the pancreas each day?
What is the main function of the acini in the pancreas?
What is the main function of the acini in the pancreas?
What is the main function of ductal cells in the pancreas?
What is the main function of ductal cells in the pancreas?
Which cells in the pancreas release amylase and lipase?
Which cells in the pancreas release amylase and lipase?
What type of tumors can occur in the endocrine pancreas?
What type of tumors can occur in the endocrine pancreas?
What is the characteristic morphologic change in the islets of Type 1 diabetes?
What is the characteristic morphologic change in the islets of Type 1 diabetes?
What is the approximate daily fluid production by the pancreas?
What is the approximate daily fluid production by the pancreas?
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Study Notes
Pancreas Functional Components
- Acini in the pancreas secrete active enzymes such as amylase and lipase for digestion.
- Ductal cells release bicarbonate-rich fluid, which helps to neutralize gastric acid and aids in digestion.
- The primary function of acini is to produce digestive enzymes, facilitating the breakdown of carbohydrates and fats.
- Ductal cells primarily serve to transport the alkaline fluid secreted by acini into the small intestine.
Daily Fluid Production
- The pancreas produces an estimated 1.5 to 2 liters of fluid each day, containing digestive enzymes and bicarbonate.
Type 1 Diabetes
- Infiltrates found in the islets of Type 1 diabetes consist of lymphocytes, indicating an autoimmune attack on insulin-producing beta cells.
- Characteristic morphologic change in the islets of Type 1 diabetes includes a reduction in beta-cell mass and disrupted architecture.
Tumors in the Endocrine Pancreas
- Tumors in the endocrine pancreas can manifest as neuroendocrine tumors, which may lead to conditions such as insulinomas and glucagonomas.
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