Podcast
Questions and Answers
Which method is used to destroy the glucagon-secreting cells in the pancreas?
Which method is used to destroy the glucagon-secreting cells in the pancreas?
- Deafferentation Vagotomy
- Parabiosis
- Surgical removal
- Treatment with alloxan (correct)
What does cobalt chloride treatment target in the pancreas?
What does cobalt chloride treatment target in the pancreas?
- Islet cells
- Insulin production
- Glucagon-secreting cells (correct)
- Nervous tissue
Which nerve disruption is carried out to affect gastrin production in the stomach?
Which nerve disruption is carried out to affect gastrin production in the stomach?
- Vagus nerve disruption
- Removal of the islets of Langerhans
- Surgical removal of the stomach
- Deafferentation Vagotomy (correct)
What is the function of gastrin in the stomach?
What is the function of gastrin in the stomach?
Why is it necessary to use highly inbred strains when transplanting tissues?
Why is it necessary to use highly inbred strains when transplanting tissues?
What is the purpose of Parabiosis as described in the text?
What is the purpose of Parabiosis as described in the text?
What is a crucial consideration when conducting whole animal studies with hormones?
What is a crucial consideration when conducting whole animal studies with hormones?
In whole animal studies, why is it important to determine whether the dose of hormone used is physiological or pharmacological?
In whole animal studies, why is it important to determine whether the dose of hormone used is physiological or pharmacological?
What is a major advantage of using an isolated perfused organ system in studies on hormone effects?
What is a major advantage of using an isolated perfused organ system in studies on hormone effects?
Why are potential interactions or side effects of hormone treatments important considerations in whole animal studies?
Why are potential interactions or side effects of hormone treatments important considerations in whole animal studies?
What factor plays a key role in determining the appropriate animal model for whole animal studies on hormones?
What factor plays a key role in determining the appropriate animal model for whole animal studies on hormones?
Why is the route of administration an important consideration in hormone studies?
Why is the route of administration an important consideration in hormone studies?
Which method involves placing catheters in the blood vessels supplying and draining an organ or tissue without removing it from the animal?
Which method involves placing catheters in the blood vessels supplying and draining an organ or tissue without removing it from the animal?
In the split-udder design for dairy cattle, why are separate catheters placed in the external pudental arteries supplying the mammary gland?
In the split-udder design for dairy cattle, why are separate catheters placed in the external pudental arteries supplying the mammary gland?
What factors should be considered in the organ perfusion/infusion model?
What factors should be considered in the organ perfusion/infusion model?
What is a key advantage of using isolated organs or tissues in situ for experimentation?
What is a key advantage of using isolated organs or tissues in situ for experimentation?
Why are blood samples taken from arterial and venous catheters in the isolated organ or tissue in situ model?
Why are blood samples taken from arterial and venous catheters in the isolated organ or tissue in situ model?
What is the purpose of supplying test compounds via arterial catheters in the isolated organ or tissue in situ model?
What is the purpose of supplying test compounds via arterial catheters in the isolated organ or tissue in situ model?
What is a limitation of in vitro models when studying the tissue being studied?
What is a limitation of in vitro models when studying the tissue being studied?
How can the results of in vitro models be affected by the incubation medium?
How can the results of in vitro models be affected by the incubation medium?
What is a common issue with the concentration of hormones used in in vitro models?
What is a common issue with the concentration of hormones used in in vitro models?
What is an advantage of using thin tissue slices in in vitro models?
What is an advantage of using thin tissue slices in in vitro models?
How does using thin tissue slices compare to perfusion in terms of technical ease?
How does using thin tissue slices compare to perfusion in terms of technical ease?
What is a challenge associated with using thin tissue slices in in vitro models?
What is a challenge associated with using thin tissue slices in in vitro models?
What is the main advantage of using immortalized cell lines in experiments?
What is the main advantage of using immortalized cell lines in experiments?
Which of the following conditions is typically required for cell culture using immortalized cell lines?
Which of the following conditions is typically required for cell culture using immortalized cell lines?
What is a key consideration when determining the appropriate duration of treatment in cell culture experiments?
What is a key consideration when determining the appropriate duration of treatment in cell culture experiments?
Which type of inhibitors can be used to determine the mechanism of action of hormones in cell culture studies?
Which type of inhibitors can be used to determine the mechanism of action of hormones in cell culture studies?
What does caution should researchers take when interpreting results obtained using immortalized cell lines?
What does caution should researchers take when interpreting results obtained using immortalized cell lines?
In what way do immortalized cell lines differ from freshly isolated primary cells?
In what way do immortalized cell lines differ from freshly isolated primary cells?
