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Questions and Answers
What is the composition of insulin?
What is the composition of insulin?
- A chain only
- B chain only
- A&B chains linked by disulfide linkage
- Pro-insulin (A chain + Connecting [C] chain + B chain) (correct)
Which cells in the pancreas secrete somatostatin?
Which cells in the pancreas secrete somatostatin?
- PP-cells (F-cells)
- Alpha cells (α-cells)
- Delta cells (δ-cells) (correct)
- Beta cells (β-cells)
What is the mechanism of insulin secretion in beta cells?
What is the mechanism of insulin secretion in beta cells?
- Glucose enters by GluT1, decreases ATP, K+ channel blockade, affects Na+ efflux, hyperpolarization of cell membrane, Ca2+ influx, exocytosis of insulin
- Glucose enters by GluT1, increases ATP, K+ channel blockade, affects K+ efflux, depolarization of cell membrane, Ca2+ influx, endocytosis of insulin
- Glucose enters by GluT2, increases ATP, K+ channel blockade, affects K+ efflux, depolarization of cell membrane, Ca2+ influx, exocytosis of insulin (correct)
- Glucose enters by GluT2, increases ATP, K+ channel blockade, affects Na+ efflux, depolarization of cell membrane, Ca2+ influx, exocytosis of insulin
Which type of cells secrete glucagon in the pancreas?
Which type of cells secrete glucagon in the pancreas?
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What maintains low basal levels of circulating insulin?
What maintains low basal levels of circulating insulin?
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